Detailed information NTG0488800

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IF705_RS11835
• Genome accession: NZ_CP062378
• Coordinates: 2339797..2340684 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain NAS_AN_079
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2334797..2345684

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF705_RS11805 (IF705_11755)	-	2334816..2334908 (+)	93	WP_010956583.1	hypothetical protein	-
IF705_RS11810 (IF705_11760)	-	2335016..2335513 (-)	498	WP_001065268.1	glutathione peroxidase	-
IF705_RS11815 (IF705_11765)	-	2335523..2335783 (-)	261	WP_001791974.1	hypothetical protein	-
IF705_RS11820 (IF705_11770)	-	2336165..2336278 (-)	114	Protein_2288	hypothetical protein	-
IF705_RS11825 (IF705_11775)	-	2336937..2338937 (-)	2001	WP_000776751.1	ABC transporter permease	-
IF705_RS11830 (IF705_11780)	-	2338934..2339689 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
IF705_RS11835 (IF705_11785)	braS	2339797..2340684 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IF705_RS11840 (IF705_11790)	braR	2340695..2341360 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IF705_RS11845 (IF705_11795)	-	2341386..2341586 (-)	201	WP_000604730.1	hypothetical protein	-
IF705_RS11850 (IF705_11800)	-	2341784..2343208 (+)	1425	WP_000953755.1	alkaline phosphatase	-
IF705_RS11855 (IF705_11805)	-	2343278..2343388 (+)	111	Protein_2295	hypothetical protein	-
IF705_RS11860 (IF705_11810)	-	2343491..2343946 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IF705_RS11865 (IF705_11815)	-	2344191..2344952 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=488800 IF705_RS11835 WP_000143425.1 2339797..2340684(-) (braS) [Staphylococcus aureus strain NAS_AN_079]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=488800 IF705_RS11835 WP_000143425.1 2339797..2340684(-) (braS) [Staphylococcus aureus strain NAS_AN_079]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1