Detailed information NTG0488714

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: IF710_RS09285
• Genome accession: NZ_CP062372
• Coordinates: 1906046..1907089 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain NAS_AN_109
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1901046..1912089

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF710_RS09255 (IF710_09230)	-	1901467..1902724 (-)	1258	Protein_1787	aminopeptidase	-
IF710_RS09260 (IF710_09235)	-	1902727..1902927 (-)	201	WP_000180460.1	DUF1128 family protein	-
IF710_RS09265 (IF710_09240)	-	1903074..1903538 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
IF710_RS09270 (IF710_09245)	-	1903545..1903820 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
IF710_RS09275 (IF710_09250)	-	1904098..1905315 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
IF710_RS09280 (IF710_09255)	vraR	1905427..1906056 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
IF710_RS09285 (IF710_09260)	vraS	1906046..1907089 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
IF710_RS09290 (IF710_09265)	liaF	1907086..1907787 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
IF710_RS09295 (IF710_09270)	-	1907802..1908188 (-)	387	WP_001110179.1	hypothetical protein	-
IF710_RS09300 (IF710_09275)	map	1908405..1909163 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
IF710_RS09305 (IF710_09280)	-	1909691..1910677 (+)	987	WP_000999714.1	aromatic acid exporter family protein	-
IF710_RS09310 (IF710_09285)	-	1911107..1911520 (-)	414	WP_025173836.1	hypothetical protein	-
IF710_RS09315 (IF710_09290)	-	1911549..1911659 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=488714 IF710_RS09285 WP_001017131.1 1906046..1907089(-) (vraS) [Staphylococcus aureus strain NAS_AN_109]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=488714 IF710_RS09285 WP_001017131.1 1906046..1907089(-) (vraS) [Staphylococcus aureus strain NAS_AN_109]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1