Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   IF722_RS07535 Genome accession   NZ_CP062360
Coordinates   1569051..1570025 (-) Length   324 a.a.
NCBI ID   WP_240025101.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NAS_AN_157     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1564051..1575025
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF722_RS07495 (IF722_07450) gcvT 1564591..1565682 (-) 1092 WP_072491749.1 glycine cleavage system aminomethyltransferase GcvT -
  IF722_RS07500 (IF722_07455) - 1565841..1566365 (-) 525 WP_029549655.1 shikimate kinase -
  IF722_RS07505 (IF722_07460) - 1566355..1566501 (-) 147 WP_001789879.1 hypothetical protein -
  IF722_RS07510 (IF722_07465) comGF 1566598..1567056 (-) 459 WP_072491748.1 competence type IV pilus minor pilin ComGF Machinery gene
  IF722_RS07515 (IF722_07470) comGE 1566974..1567273 (-) 300 WP_172452442.1 competence protein ComGE Machinery gene
  IF722_RS07520 (IF722_07475) comGD 1567260..1567706 (-) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  IF722_RS07525 (IF722_07480) comGC 1567684..1567995 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  IF722_RS07530 (IF722_07485) comGB 1568009..1569079 (-) 1071 WP_000776418.1 competence type IV pilus assembly protein ComGB Machinery gene
  IF722_RS07535 (IF722_07490) comGA 1569051..1570025 (-) 975 WP_240025101.1 competence type IV pilus ATPase ComGA Machinery gene
  IF722_RS07540 (IF722_07495) - 1570077..1570700 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  IF722_RS07545 (IF722_07500) - 1570697..1571026 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  IF722_RS07550 (IF722_07505) - 1571026..1572012 (-) 987 WP_000161315.1 ROK family glucokinase -
  IF722_RS07555 (IF722_07510) - 1572009..1572212 (-) 204 WP_000087561.1 YqgQ family protein -
  IF722_RS07560 (IF722_07515) - 1572193..1573656 (-) 1464 WP_001017867.1 rhomboid family intramembrane serine protease -
  IF722_RS07565 (IF722_07520) - 1573668..1574207 (-) 540 WP_000164552.1 5-formyltetrahydrofolate cyclo-ligase -
  IF722_RS07570 (IF722_07525) rpmG 1574416..1574565 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36883.93 Da        Isoelectric Point: 8.8516

>NTDB_id=488451 IF722_RS07535 WP_240025101.1 1569051..1570025(-) (comGA) [Staphylococcus aureus strain NAS_AN_157]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGVSVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=488451 IF722_RS07535 WP_240025101.1 1569051..1570025(-) (comGA) [Staphylococcus aureus strain NAS_AN_157]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTAATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGACCTACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCCATT
TTAAGGCTATTAGAAATGGGCGTTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

99.691

100

0.997
  comGA Staphylococcus aureus N315

99.691

100

0.997