Detailed information NTG0488296

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IF733_RS10085
• Genome accession: NZ_CP062352
• Coordinates: 2069973..2070860 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain NAS_AN_233
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2064973..2075860

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF733_RS10055 (IF733_10000)	-	2065705..2066466 (+)	762	WP_000323441.1	alpha/beta hydrolase family protein	-
IF733_RS10060 (IF733_10005)	-	2066711..2067166 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IF733_RS13665	-	2067288..2067389 (+)	102	WP_000731976.1	SE2200 family small protein	-
IF733_RS10070 (IF733_10015)	-	2067449..2068873 (-)	1425	WP_000953755.1	alkaline phosphatase	-
IF733_RS10075 (IF733_10020)	-	2069071..2069271 (+)	201	WP_031791006.1	hypothetical protein	-
IF733_RS10080 (IF733_10025)	braR	2069297..2069962 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IF733_RS10085 (IF733_10030)	braS	2069973..2070860 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IF733_RS10090 (IF733_10035)	-	2070968..2071723 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
IF733_RS10095 (IF733_10040)	-	2071720..2073720 (+)	2001	WP_000776751.1	ABC transporter permease	-
IF733_RS10100 (IF733_10045)	-	2074379..2074492 (+)	114	Protein_1957	hypothetical protein	-
IF733_RS10105 (IF733_10050)	-	2074874..2075134 (+)	261	WP_001791974.1	hypothetical protein	-
IF733_RS10110 (IF733_10055)	-	2075144..2075641 (+)	498	WP_001065268.1	glutathione peroxidase	-
IF733_RS10115 (IF733_10060)	-	2075749..2075841 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=488296 IF733_RS10085 WP_000143425.1 2069973..2070860(+) (braS) [Staphylococcus aureus strain NAS_AN_233]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=488296 IF733_RS10085 WP_000143425.1 2069973..2070860(+) (braS) [Staphylococcus aureus strain NAS_AN_233]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1