Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   IF736_RS13385 Genome accession   NZ_CP062350
Coordinates   2694493..2695209 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain NAS_AN_250     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2689493..2700209
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF736_RS13365 (IF736_13285) - 2690577..2691527 (+) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -
  IF736_RS13370 (IF736_13290) - 2691676..2693160 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  IF736_RS13375 (IF736_13295) - 2693157..2694116 (+) 960 WP_001253314.1 carbohydrate kinase -
  IF736_RS13380 (IF736_13300) - 2694304..2694413 (-) 110 Protein_2601 hypothetical protein -
  IF736_RS13385 (IF736_13305) agrA 2694493..2695209 (-) 717 WP_000688498.1 LytTR family DNA-binding domain-containing protein Regulator
  IF736_RS13390 (IF736_13310) - 2695228..2696512 (-) 1285 Protein_2603 sensor histidine kinase -
  IF736_RS13395 (IF736_13315) - 2696542..2696685 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide -
  IF736_RS13400 (IF736_13320) - 2696688..2697251 (-) 564 WP_001105696.1 accessory gene regulator ArgB-like protein -
  IF736_RS13775 (IF736_13325) - 2697487..2697621 (+) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  IF736_RS13410 (IF736_13330) - 2698218..2699003 (-) 786 WP_240018949.1 carbon-nitrogen family hydrolase -
  IF736_RS13415 (IF736_13335) - 2699364..2699990 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=488258 IF736_RS13385 WP_000688498.1 2694493..2695209(-) (agrA) [Staphylococcus aureus strain NAS_AN_250]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=488258 IF736_RS13385 WP_000688498.1 2694493..2695209(-) (agrA) [Staphylococcus aureus strain NAS_AN_250]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTTAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996