Detailed information NTG0488213

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IF738_RS12275
• Genome accession: NZ_CP062348
• Coordinates: 2417719..2418606 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain NAS_AN_260
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2412719..2423606

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF738_RS12245 (IF738_12195)	-	2412738..2412830 (+)	93	WP_010956583.1	hypothetical protein	-
IF738_RS12250 (IF738_12200)	-	2412938..2413435 (-)	498	WP_001065268.1	glutathione peroxidase	-
IF738_RS12255 (IF738_12205)	-	2413445..2413705 (-)	261	WP_001791974.1	hypothetical protein	-
IF738_RS12260 (IF738_12210)	-	2414087..2414200 (-)	114	Protein_2375	hypothetical protein	-
IF738_RS12265 (IF738_12215)	-	2414859..2416859 (-)	2001	WP_000776740.1	ABC transporter permease	-
IF738_RS12270 (IF738_12220)	-	2416856..2417611 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
IF738_RS12275 (IF738_12225)	braS	2417719..2418606 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IF738_RS12280 (IF738_12230)	braR	2418617..2419282 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IF738_RS12285 (IF738_12235)	-	2419308..2419508 (-)	201	WP_000604727.1	hypothetical protein	-
IF738_RS12290 (IF738_12240)	-	2419706..2421130 (+)	1425	WP_000953748.1	alkaline phosphatase	-
IF738_RS12295 (IF738_12245)	-	2421200..2421310 (+)	111	WP_001791296.1	hypothetical protein	-
IF738_RS12300 (IF738_12250)	-	2421413..2421868 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IF738_RS12305 (IF738_12255)	-	2422113..2422874 (-)	762	Protein_2384	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=488213 IF738_RS12275 WP_000143417.1 2417719..2418606(-) (braS) [Staphylococcus aureus strain NAS_AN_260]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=488213 IF738_RS12275 WP_000143417.1 2417719..2418606(-) (braS) [Staphylococcus aureus strain NAS_AN_260]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99