Detailed information NTG0487968

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IF748_RS11435
• Genome accession: NZ_CP062336
• Coordinates: 2298029..2298916 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain NAS_NP_161
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2293029..2303916

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF748_RS11405 (IF748_11345)	-	2293048..2293140 (+)	93	WP_010956583.1	hypothetical protein	-
IF748_RS11410 (IF748_11350)	-	2293248..2293745 (-)	498	WP_001065268.1	glutathione peroxidase	-
IF748_RS11415 (IF748_11355)	-	2293755..2294015 (-)	261	WP_001791974.1	hypothetical protein	-
IF748_RS11420 (IF748_11360)	-	2294397..2294510 (-)	114	Protein_2208	hypothetical protein	-
IF748_RS11425 (IF748_11365)	-	2295169..2297169 (-)	2001	WP_000776740.1	ABC transporter permease	-
IF748_RS11430 (IF748_11370)	-	2297166..2297921 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
IF748_RS11435 (IF748_11375)	braS	2298029..2298916 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IF748_RS11440 (IF748_11380)	braR	2298927..2299592 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IF748_RS11445 (IF748_11385)	-	2299618..2299818 (-)	201	WP_000604727.1	hypothetical protein	-
IF748_RS11450 (IF748_11390)	-	2300016..2301440 (+)	1425	WP_000953748.1	alkaline phosphatase	-
IF748_RS11455 (IF748_11395)	-	2301510..2301620 (+)	111	WP_001791296.1	hypothetical protein	-
IF748_RS11460 (IF748_11400)	-	2301723..2302178 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IF748_RS11465 (IF748_11405)	-	2302423..2303184 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=487968 IF748_RS11435 WP_000143417.1 2298029..2298916(-) (braS) [Staphylococcus aureus strain NAS_NP_161]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=487968 IF748_RS11435 WP_000143417.1 2298029..2298916(-) (braS) [Staphylococcus aureus strain NAS_NP_161]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99