Detailed information NTG0487963

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: IF748_RS07920
• Genome accession: NZ_CP062336
• Coordinates: 1606376..1607419 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain NAS_NP_161
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1601376..1612419

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF748_RS07890 (IF748_07855)	-	1601798..1603054 (-)	1257	WP_072419726.1	aminopeptidase	-
IF748_RS07895 (IF748_07860)	-	1603057..1603257 (-)	201	WP_000180460.1	DUF1128 family protein	-
IF748_RS07900 (IF748_07865)	-	1603404..1603868 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
IF748_RS07905 (IF748_07870)	-	1603875..1604150 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
IF748_RS07910 (IF748_07875)	-	1604428..1605645 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
IF748_RS07915 (IF748_07880)	vraR	1605757..1606386 (-)	630	WP_000153536.1	two-component system response regulator VraR	Regulator
IF748_RS07920 (IF748_07885)	vraS	1606376..1607419 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
IF748_RS07925 (IF748_07890)	liaF	1607416..1608117 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
IF748_RS07930 (IF748_07895)	-	1608132..1608518 (-)	387	WP_001110179.1	hypothetical protein	-
IF748_RS07935 (IF748_07900)	map	1608735..1609493 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
IF748_RS07940 (IF748_07905)	-	1610024..1611010 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
IF748_RS07945 (IF748_07910)	-	1611441..1611854 (-)	414	WP_001566709.1	hypothetical protein	-
IF748_RS07950 (IF748_07915)	-	1611883..1611993 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=487963 IF748_RS07920 WP_001017131.1 1606376..1607419(-) (vraS) [Staphylococcus aureus strain NAS_NP_161]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=487963 IF748_RS07920 WP_001017131.1 1606376..1607419(-) (vraS) [Staphylococcus aureus strain NAS_NP_161]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGCATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1