Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraS   Type   Regulator
Locus tag   IF761_RS00515 Genome accession   NZ_CP062329
Coordinates   92546..93589 (+) Length   347 a.a.
NCBI ID   WP_001017131.1    Uniprot ID   A0A0D1IMN4
Organism   Staphylococcus aureus strain NAS_OP_026     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 87546..98589
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF761_RS00485 (IF761_00470) - 87975..88085 (+) 111 WP_001790257.1 hypothetical protein -
  IF761_RS00490 (IF761_00475) - 88114..88527 (+) 414 WP_025173836.1 hypothetical protein -
  IF761_RS00495 (IF761_00480) - 88958..89944 (-) 987 WP_000999714.1 aromatic acid exporter family protein -
  IF761_RS00500 (IF761_00485) map 90472..91230 (+) 759 WP_000636142.1 type I methionyl aminopeptidase -
  IF761_RS00505 (IF761_00490) - 91447..91833 (+) 387 WP_001110179.1 hypothetical protein -
  IF761_RS00510 (IF761_00495) liaF 91848..92549 (+) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  IF761_RS00515 (IF761_00500) vraS 92546..93589 (+) 1044 WP_001017131.1 sensor histidine kinase Regulator
  IF761_RS00520 (IF761_00505) vraR 93579..94208 (+) 630 WP_000153530.1 two-component system response regulator VraR Regulator
  IF761_RS00525 (IF761_00510) - 94320..95537 (-) 1218 WP_000037079.1 YihY/virulence factor BrkB family protein -
  IF761_RS00530 (IF761_00515) - 95815..96090 (-) 276 WP_000428172.1 YtxH domain-containing protein -
  IF761_RS00535 (IF761_00520) - 96097..96561 (-) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  IF761_RS00540 (IF761_00525) - 96708..96908 (+) 201 WP_000180460.1 DUF1128 family protein -
  IF761_RS00545 (IF761_00530) - 96911..98167 (+) 1257 WP_001789555.1 aminopeptidase -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 40044.52 Da        Isoelectric Point: 6.0577

>NTDB_id=487807 IF761_RS00515 WP_001017131.1 92546..93589(+) (vraS) [Staphylococcus aureus strain NAS_OP_026]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=487807 IF761_RS00515 WP_001017131.1 92546..93589(+) (vraS) [Staphylococcus aureus strain NAS_OP_026]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(249-340)

Histidine kinase (HisKA_3)

(147-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0D1IMN4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraS Staphylococcus aureus N315

100

100

1