Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   IF775_RS13230 Genome accession   NZ_CP062318
Coordinates   2691291..2692007 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain NAS_OP_132     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2686291..2697007
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF775_RS13210 (IF775_13150) - 2687383..2688333 (+) 951 WP_029625646.1 LacI family DNA-binding transcriptional regulator -
  IF775_RS13215 (IF775_13155) - 2688482..2689966 (+) 1485 WP_000141435.1 sucrose-6-phosphate hydrolase -
  IF775_RS13220 (IF775_13160) - 2689963..2690922 (+) 960 WP_001253302.1 carbohydrate kinase -
  IF775_RS13225 (IF775_13165) - 2691110..2691219 (-) 110 Protein_2570 hypothetical protein -
  IF775_RS13230 (IF775_13170) agrA 2691291..2692007 (-) 717 WP_000688498.1 LytTR family DNA-binding domain-containing protein Regulator
  IF775_RS13235 (IF775_13175) - 2692026..2693318 (-) 1293 WP_001657119.1 GHKL domain-containing protein -
  IF775_RS13240 (IF775_13180) - 2693343..2693483 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide -
  IF775_RS13245 (IF775_13185) agrB 2693480..2694049 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  IF775_RS13250 hld 2694339..2694419 (+) 81 WP_000046022.1 delta-hemolysin -
  IF775_RS13255 (IF775_13195) - 2695019..2695804 (-) 786 WP_000867939.1 carbon-nitrogen family hydrolase -
  IF775_RS13260 (IF775_13200) - 2696165..2696791 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=487641 IF775_RS13230 WP_000688498.1 2691291..2692007(-) (agrA) [Staphylococcus aureus strain NAS_OP_132]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=487641 IF775_RS13230 WP_000688498.1 2691291..2692007(-) (agrA) [Staphylococcus aureus strain NAS_OP_132]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996