Detailed information NTG0048764

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SPSE_RS04060
• Genome accession: NC_017568
• Coordinates: 928218..929261 (+)
• Length: 347 a.a.
• NCBI ID: WP_014613481.1
• Uniprot ID: -
• Organism: Staphylococcus pseudintermedius ED99
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 923218..934261

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPSE_RS04035 (SPSE_0862)	-	923474..924196 (+)	723	WP_014613476.1	type 1 glutamine amidotransferase	-
SPSE_RS04040 (SPSE_0863)	-	925164..926162 (-)	999	WP_014613477.1	FUSC family protein	-
SPSE_RS04045 (SPSE_0864)	map	926259..927020 (+)	762	WP_014613478.1	type I methionyl aminopeptidase	-
SPSE_RS04050 (SPSE_0865)	-	927118..927507 (+)	390	WP_014613479.1	hypothetical protein	-
SPSE_RS04055 (SPSE_0866)	liaF	927520..928221 (+)	702	WP_014613480.1	cell wall-active antibiotics response protein LiaF	-
SPSE_RS04060 (SPSE_0867)	vraS	928218..929261 (+)	1044	WP_014613481.1	sensor histidine kinase	Regulator
SPSE_RS04065 (SPSE_0868)	vraR	929251..929880 (+)	630	WP_014613482.1	response regulator transcription factor	Regulator
SPSE_RS04070 (SPSE_0869)	-	930447..931028 (-)	582	WP_014613483.1	beta-class carbonic anhydrase	-
SPSE_RS04075 (SPSE_0870)	-	931061..932398 (-)	1338	WP_014613484.1	YihY/virulence factor BrkB family protein	-
SPSE_RS04080 (SPSE_0871)	-	932614..932901 (-)	288	WP_014613485.1	YtxH domain-containing protein	-
SPSE_RS04085 (SPSE_0872)	-	932909..933367 (-)	459	WP_014613486.1	low molecular weight protein-tyrosine-phosphatase	-
SPSE_RS04090 (SPSE_0873)	-	933501..933704 (+)	204	WP_014613487.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39939.24 Da
• Isoelectric Point: 5.0435

>NTDB_id=48764 SPSE_RS04060 WP_014613481.1 928218..929261(+) (vraS) [Staphylococcus pseudintermedius ED99]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWLKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDEKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=48764 SPSE_RS04060 WP_014613481.1 928218..929261(+) (vraS) [Staphylococcus pseudintermedius ED99]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATTGACAA
AGTGTTCACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGTATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATTGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGCTCAAGCAA
CAAATCGTTCGTGCCTTTGAAGGTGAAACAGTGGGCATCAATGATCAACAACTCGAGCTGTATAATGAAACGATTGAATT
ATATCAAGCACTCGTCCCATTAAATCAAGAATTGCATAAAATGCGAATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGACAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAAGAAACAGATTTAGCACCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGCGCTCTGTTACTTCACTTGAGACCTATAGGATTGAAGG
ACAAATCGTTAGGTGAGGGAATTAAATCGCTTGTGACGGATCTACAACGTAAAGTACCCATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTACCTAAAGGCATTGAGGATCACCTTTTTAGAATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGGACGCAAGTAACGGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGAAAAGTTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACA
TTTCATATCGTCTCATTACCTGATGCGGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.862	100	0.839