Detailed information NTG0486119

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: IGB10_RS16635
• Genome accession: NZ_CP062074
• Coordinates: 3394843..3396006 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain BSC16a
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3389843..3401006

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IGB10_RS16605 (IGB10_16605)	-	3390107..3390526 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
IGB10_RS16610 (IGB10_16610)	comFC	3390600..3391289 (-)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
IGB10_RS16615 (IGB10_16615)	-	3391295..3391579 (-)	285	WP_003151389.1	late competence development ComFB family protein	-
IGB10_RS16620 (IGB10_16620)	comFA	3391637..3393022 (-)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
IGB10_RS16625 (IGB10_16625)	-	3393131..3393979 (-)	849	WP_032876160.1	DegV family protein	-
IGB10_RS16630 (IGB10_16630)	degU	3394077..3394766 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
IGB10_RS16635 (IGB10_16635)	degS	3394843..3396006 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
IGB10_RS16640 (IGB10_16640)	-	3396229..3396876 (+)	648	WP_007614107.1	YigZ family protein	-
IGB10_RS16645 (IGB10_16645)	-	3396881..3398062 (+)	1182	WP_032876157.1	LCP family protein	-
IGB10_RS16650 (IGB10_16650)	-	3398161..3399237 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
IGB10_RS16655 (IGB10_16655)	-	3399370..3400566 (-)	1197	WP_032876154.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=486119 IGB10_RS16635 WP_007407484.1 3394843..3396006(-) (degS) [Bacillus velezensis strain BSC16a]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=486119 IGB10_RS16635 WP_007407484.1 3394843..3396006(-) (degS) [Bacillus velezensis strain BSC16a]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951