Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   TL13_RS00350 Genome accession   NC_021213
Coordinates   60781..62718 (+) Length   645 a.a.
NCBI ID   WP_015646242.1    Uniprot ID   -
Organism   Streptococcus suis TL13     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 55781..67718
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TL13_RS00325 (TL13_0067) - 55895..56518 (+) 624 WP_015646237.1 HAD-IA family hydrolase -
  TL13_RS00330 (TL13_0068) comR 56623..57522 (+) 900 WP_015646238.1 helix-turn-helix domain-containing protein Regulator
  TL13_RS00335 (TL13_0069) - 57729..58949 (+) 1221 WP_015646239.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  TL13_RS00345 (TL13_0071) - 59140..60663 (+) 1524 WP_015646241.1 Heme/copper-type cytochrome/quinol oxidase subunit 1 -
  TL13_RS00350 (TL13_0073) hexB 60781..62718 (+) 1938 WP_015646242.1 DNA mismatch repair endonuclease MutL Machinery gene
  TL13_RS00355 (TL13_0074) ruvA 62757..63347 (+) 591 WP_015646243.1 Holliday junction branch migration protein RuvA Machinery gene
  TL13_RS00360 (TL13_0075) - 63783..64352 (+) 570 WP_015646244.1 DNA-3-methyladenine glycosylase I -
  TL13_RS00365 (TL13_0076) cinA 64389..65570 (+) 1182 WP_015646245.1 competence/damage-inducible protein A Machinery gene
  TL13_RS00370 (TL13_0077) recA 65622..66773 (+) 1152 WP_015646246.1 recombinase RecA Machinery gene
  TL13_RS00375 (TL13_0078) spx 67009..67407 (+) 399 WP_002939362.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72903.07 Da        Isoelectric Point: 5.0613

>NTDB_id=48596 TL13_RS00350 WP_015646242.1 60781..62718(+) (hexB) [Streptococcus suis TL13]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISIEEAGLKMIQITDNGEGITPDEVALALRRHATSK
IKSQSDLFRIRTLGFRGEALPSIASVSQMVIETATADSAHGLHLEAKGGVIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFALVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENK
PTSVQFAERQSVDSEDQEHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALDLVHKMDALRQVGVNLEEYGANQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=48596 TL13_RS00350 WP_015646242.1 60781..62718(+) (hexB) [Streptococcus suis TL13]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCGGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTATTGAAGAGGCTGGCCTTAAAA
TGATTCAAATCACGGATAACGGTGAGGGGATTACCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAGTCAATCGGATTTGTTTCGTATTCGCACCCTCGGTTTTCGTGGAGAAGCTCTGCCTTCCATTGCTTCTGTCAG
TCAGATGGTTATTGAGACAGCTACGGCAGACTCTGCACATGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCCGTTAGTCGTCCAGTTGGTACGCAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAC
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCTTT
TGCCTTAGTAAACGAAGGACGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCTGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATCTGGATTTTCAGATTTCAGGTTACGTTTCCTTGCCA
GAGTTGACTCGTGCCAACCGCAACTACATTTCCATTTTCATCAACGGTCGTTATATCAAGAATTTTTTGCTGAATCGAGC
GATTTTGGAAGGTTACGGCAGTAAGTTGATGGTTGGACGCTTTCCGTTGGCAGTCATTTCTATAGAAATTGACCCCTATC
TTGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCGCTTAAAGAGCAGGATTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAGAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTCTTAA
AACCAGATGTTGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATCGGCAAGAGATTGTTGAGTCACCTGTCGAAAATAAA
CCTACATCTGTTCAATTTGCAGAACGTCAGTCGGTGGATTCAGAAGATCAGGAGCATCCTAATCTAAGCGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGAGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAAATGCATGGGA
CGTATTTATTTGCGCAAGGTAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAGAGGGTCAAATACGAATAC
TACCGTGAGAAAATTGGACAGGTTGACAATTCAGCTCAACAGTTATTGGTGCCGTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTGACCTTGTCCACAAAATGGATGCCCTTCGTCAAGTTGGTGTCAACTTGGAAGAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAAGAGATTGAGTCTGGCATTTATGAGATGTGCGACATGTTGCTCTTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCTATCATGATGTCTTGTAAACGGTCAATCAAGGCCAACCA
TGCTTTGGATGATTATTCGGCGCGTGATTTATTGAGACAATTGTCTTACTGCCAAAATCCCTATAACTGCCCGCACGGTC
GTCCAGTTTTAGTACATTTTAGCAAGTCAGATATGGAAAAGATGTTCCGTCGCATTCAGGAAAATCACACGAGTTTGCGA
GAATTGGGCAAGTATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

MutL C terminal dimerisation domain (MutL_C)

(447-589)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.462

100

0.73