Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   I872_RS05500 Genome accession   NC_021175
Coordinates   1100939..1102273 (-) Length   444 a.a.
NCBI ID   WP_015605156.1    Uniprot ID   A0ABM5NKB5
Organism   Streptococcus cristatus AS 1.3089     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1095939..1107273
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I872_RS10920 (I872_05490) - 1096653..1096822 (+) 170 Protein_1069 DUF3042 family protein -
  I872_RS05475 (I872_05495) - 1097068..1097466 (-) 399 WP_015605151.1 hypothetical protein -
  I872_RS05485 (I872_05505) - 1097826..1098986 (-) 1161 WP_015605153.1 ABC transporter permease subunit -
  I872_RS05490 (I872_05510) - 1098983..1099846 (-) 864 WP_015605154.1 ABC transporter ATP-binding protein -
  I872_RS05500 (I872_05520) comD/blpH 1100939..1102273 (-) 1335 WP_015605156.1 sensor histidine kinase Regulator
  I872_RS05505 (I872_05525) comE/blpR 1102306..1103037 (-) 732 WP_015605157.1 response regulator transcription factor Regulator
  I872_RS05510 (I872_05530) - 1103039..1103380 (-) 342 WP_015605158.1 LytTR family DNA-binding domain-containing protein -
  I872_RS05515 (I872_05535) - 1103563..1104135 (-) 573 WP_015605159.1 TetR/AcrR family transcriptional regulator -
  I872_RS05520 (I872_05540) - 1104262..1105104 (+) 843 WP_015605160.1 DegV family protein -
  I872_RS05525 (I872_05545) - 1105195..1105965 (+) 771 Protein_1078 XRE family transcriptional regulator -
  I872_RS05530 (I872_05550) - 1106147..1106839 (-) 693 WP_015605162.1 phosphoglycerate mutase -

Sequence

Protein


Download         Length: 444 a.a.        Molecular weight: 51738.52 Da        Isoelectric Point: 6.5087

>NTDB_id=48522 I872_RS05500 WP_015605156.1 1100939..1102273(-) (comD/blpH) [Streptococcus cristatus AS 1.3089]
MPRIIQVVLLVFEMIALSFLFSRISGIKLTWIKYVLIPFIYIFFNLLLFVLFSETFLTYLDLPVYFLIFSLLLTRPSSIP
ITLSIFYGLFPVVLWNLLYRILTFFVIPIFGLEYNQLINEEQLILNITAFVASLLSLWIPSLLHYKFKRLGEFRLNEADK
HLVIFLNISMVFYIVFVQFFSYLEITHNVVNLPYRKFIVIIYIILFLSSVNILDRNLRERIQQQLSEQRELQLRNMSDYS
QHIEELYNELRSFRHDYINILRSLKLGIDTHDLPAIEQIYNQVLKDSGQALNQSKYDLGRLSNIHNDALKSVLSAKFLEA
QSKGIEIGLEVPQEIKPQGMELLDFITIVSILADNAMEAAVETSHPVVSFAFLEQEGRQIFIVENTIKEFSIPSDTIFKK
GFSTKGENRGLGLSNVQNIISHYPNVSLRTTSHDYSFRQELEIK

Nucleotide


Download         Length: 1335 bp        

>NTDB_id=48522 I872_RS05500 WP_015605156.1 1100939..1102273(-) (comD/blpH) [Streptococcus cristatus AS 1.3089]
ATGCCAAGAATAATACAAGTTGTTTTACTTGTTTTCGAAATGATAGCTCTGTCTTTCTTATTTTCACGTATCAGTGGAAT
TAAGTTGACATGGATTAAGTACGTCTTAATACCTTTTATTTATATATTTTTTAATCTTCTGCTTTTTGTCTTATTTAGTG
AAACTTTTTTAACTTACTTAGATCTTCCAGTTTATTTTTTAATTTTTTCTTTATTATTAACTAGACCGAGTTCTATTCCT
ATAACGTTATCTATCTTTTATGGTCTTTTCCCAGTTGTTCTTTGGAATCTTCTATATCGTATATTAACTTTTTTTGTTAT
TCCTATTTTCGGTTTGGAATATAACCAACTAATAAATGAAGAACAGCTTATTTTAAATATTACGGCTTTTGTAGCTAGTT
TACTATCGTTATGGATCCCAAGTTTACTACATTATAAATTTAAGCGGTTAGGAGAATTTAGATTAAATGAGGCTGATAAA
CACCTAGTCATTTTCCTTAATATATCCATGGTTTTTTATATTGTATTTGTACAATTTTTCTCTTATTTAGAAATAACTCA
TAATGTGGTTAATTTGCCATATAGAAAATTTATTGTGATAATTTATATTATTCTCTTTCTCAGTTCGGTAAATATCCTAG
ACCGTAATTTGCGAGAGCGAATTCAACAGCAGTTAAGTGAACAAAGAGAGTTACAGTTGAGAAATATGTCCGATTACAGT
CAGCACATTGAAGAACTTTATAATGAGTTGCGAAGTTTTCGGCATGATTACATCAATATTTTAAGGAGTCTGAAGTTGGG
AATTGATACGCACGATTTACCAGCCATCGAGCAGATTTATAACCAAGTCCTTAAAGACTCAGGTCAAGCGCTCAACCAAT
CTAAATATGATTTGGGTCGTCTGTCCAATATCCACAATGATGCTCTCAAGAGCGTCTTGTCAGCAAAATTTCTAGAAGCT
CAGAGCAAGGGAATAGAAATTGGCTTGGAAGTTCCGCAAGAAATTAAACCTCAAGGAATGGAATTGCTTGATTTTATTAC
GATTGTTTCCATACTGGCTGATAATGCTATGGAAGCAGCAGTGGAGACTAGTCATCCAGTGGTTTCTTTTGCCTTTTTAG
AGCAGGAAGGTAGACAGATTTTTATTGTTGAGAATACAATAAAAGAGTTTTCTATCCCTTCCGATACTATTTTTAAAAAG
GGCTTTAGCACTAAAGGAGAAAATAGAGGGCTTGGTCTCTCCAATGTTCAAAATATTATCAGCCACTATCCCAATGTTTC
TCTGCGAACCACTAGTCATGATTACTCTTTTAGACAAGAGTTGGAGATAAAATGA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(340-443)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

41.315

95.946

0.396