Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   HI837_RS11830 Genome accession   NZ_CP061817
Coordinates   2433749..2435101 (-) Length   450 a.a.
NCBI ID   WP_407045603.1    Uniprot ID   -
Organism   Enterococcus faecium strain A6521     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 2432249..2436302 2433749..2435101 within 0


Gene organization within MGE regions


Location: 2432249..2436302
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HI837_RS11825 (HI837_011825) - 2432249..2433544 (-) 1296 WP_002296623.1 ISL3 family transposase -
  HI837_RS11830 (HI837_011830) pepF 2433749..2435101 (-) 1353 WP_407045603.1 oligoendopeptidase F Regulator
  HI837_RS11835 (HI837_011835) - 2435124..2436302 (+) 1179 WP_106914365.1 IS256 family transposase -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 52028.69 Da        Isoelectric Point: 5.1527

>NTDB_id=484850 HI837_RS11830 WP_407045603.1 2433749..2435101(-) (pepF) [Enterococcus faecium strain A6521]
MCCGNSILQKGLPFFYLHKIFYTLVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAAFKGLYSVYEQFRNT
FASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVDVVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLG
EAPITFTYEEAKEKALEALKPMGEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHYLDGFKGTVFRQTQFAEFEHFMH
TEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEIKFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENY
LAYLKAGNSDYPVEVMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=484850 HI837_RS11830 WP_407045603.1 2433749..2435101(-) (pepF) [Enterococcus faecium strain A6521]
ATGTGTTGTGGTAACTCTATTCTACAGAAGGGACTTCCTTTTTTCTATTTACACAAAATATTTTACACTCTCGTTTTGAA
TAATGCAGATCTAGTTTTTCCAACGATTGAAGGAGAAAATGGTGAAATAGTCCAATTATCTCATGGCGTGTATGGTCAGT
TGCTAGAAAGCACGGATCGAAGGGTGCGCGAAGCAGCATTTAAGGGGTTGTACAGTGTTTACGAACAATTTAGAAATACA
TTTGCTTCTACTTTAGGCACACATATAAAAGGACATAATTTTAAAGCGAAAGTCCGTAATTACAGCTCTGCCAGAGAAGC
GTCTTTGAGCAATAATCATATTCCTGAAAGTGTATACGATACTTTGGTAGACGTGGTAAACAAGCATTTGCCTTTGTTAC
ATCGATACATGGAATTACGGAAACGTTTATTAGAAGTGGAAAAACTGCACATGTATGATCTTTATACACCGGTCTTAGGG
GAAGCTCCAATTACCTTTACGTACGAAGAAGCAAAAGAAAAAGCTTTAGAAGCACTGAAACCAATGGGTGAAGAATACAT
GGCCATCGTAGAAAAAGCATTCTCTGAACGTTGGATCGATGTTGTCGAAAATAAAGGGAAACGAAGCGGTGCTTATTCTT
CGGGAAGCTATGACACAAATCCATATATTTTATTGAATTGGCATGATACGCTGGATCAGCTATTTACGCTTGTCCACGAA
ATGGGACATAGTGTTCATAGTTATTTCACTCGTTCGAACCAGCCTTATGTGTACGGCGACTACTCCATCTTTTTAGCAGA
AATTGCTTCGACAACGAATGAAAATATCCTAACGGAGTATTTATTGGAAACAGAAAAAGACCCTCGTGTACGGGCTTATG
TACTCAACCATTACTTGGATGGGTTTAAAGGAACAGTTTTCCGCCAGACACAATTCGCTGAATTCGAGCATTTCATGCAT
ACGGAAGATGAAAAAGGTGTGCCATTGACTAGTGAATACCTAAGTGATAGTTATGGTAAATTGAATGCAAAATATTATGG
TCCAGCAGTCGAAGAAGACCCAGAAATTAAATTCGAATGGTCACGGATACCGCATTTTTATTATAATTACTATGTTTTCC
AATACTCGACTGGCTTTTCTGCTGCTTCAGCACTGGCGAAGAAAATACTAAACCAGGAACCAGAGGCACTAGAGAACTAC
TTGGCTTACCTAAAAGCAGGTAACAGCGATTATCCTGTGGAAGTAATGAAAAAAGCAGGAGTTGATATGACACAGGCTGC
ATATATTGAAGATGCAATGTCGATGTTTGAACAACGTCTAAATGAATTAGAAGAATTGATCGATCGTTTATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(54-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

60.706

94.444

0.573