Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   J7U24_RS09065 Genome accession   NZ_CP072440
Coordinates   1733653..1733946 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain S24730     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1728653..1738946
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U24_RS09025 (J7U24_09000) - 1729055..1729498 (-) 444 WP_041829335.1 hypothetical protein -
  J7U24_RS09030 - 1729572..1729910 (-) 339 WP_224103197.1 CPBP family intramembrane glutamic endopeptidase -
  J7U24_RS09035 - 1729954..1730229 (-) 276 WP_372434690.1 CAAX protease -
  J7U24_RS09040 (J7U24_09010) - 1730241..1730438 (-) 198 WP_014727723.1 helix-turn-helix transcriptional regulator -
  J7U24_RS09045 (J7U24_09015) - 1730687..1731880 (-) 1194 WP_014608740.1 acetate kinase -
  J7U24_RS09050 (J7U24_09020) comGH 1731936..1732892 (-) 957 WP_372434691.1 class I SAM-dependent methyltransferase Machinery gene
  J7U24_RS09055 (J7U24_09025) comGG 1732937..1733254 (-) 318 WP_011681685.1 competence type IV pilus minor pilin ComGG Machinery gene
  J7U24_RS09060 (J7U24_09030) comGF 1733232..1733669 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  J7U24_RS09065 (J7U24_09035) comGE 1733653..1733946 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  J7U24_RS09070 (J7U24_09040) comGD 1733918..1734346 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  J7U24_RS09075 (J7U24_09045) comGC 1734306..1734632 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  J7U24_RS09080 (J7U24_09050) comGB 1734629..1735729 (-) 1101 WP_142350125.1 competence type IV pilus assembly protein ComGB Machinery gene
  J7U24_RS09085 (J7U24_09055) comGA/cglA/cilD 1735611..1736552 (-) 942 WP_071417491.1 competence type IV pilus ATPase ComGA Machinery gene
  J7U24_RS09090 (J7U24_09060) - 1736633..1736995 (-) 363 WP_014622006.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=483341 J7U24_RS09065 WP_011226625.1 1733653..1733946(-) (comGE) [Streptococcus thermophilus strain S24730]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=483341 J7U24_RS09065 WP_011226625.1 1733653..1733946(-) (comGE) [Streptococcus thermophilus strain S24730]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361