Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   J7U23_RS08145 Genome accession   NZ_CP072435
Coordinates   1578443..1579246 (+) Length   267 a.a.
NCBI ID   WP_224103634.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24736     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1573443..1584246
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U23_RS08125 (J7U23_08055) - 1574808..1575050 (-) 243 WP_096811635.1 Blp family class II bacteriocin -
  J7U23_RS08130 - 1575301..1575702 (-) 402 WP_011226490.1 hypothetical protein -
  J7U23_RS08135 (J7U23_08060) - 1576689..1576919 (-) 231 WP_011226494.1 bacteriocin class II family protein -
  J7U23_RS08140 (J7U23_08065) - 1577175..1577906 (+) 732 WP_179971035.1 LytTR family DNA-binding domain-containing protein -
  J7U23_RS08145 comD/blpH 1578443..1579246 (+) 804 WP_224103634.1 ATP-binding protein Regulator
  J7U23_RS08150 (J7U23_08075) - 1579264..1579425 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  J7U23_RS08155 (J7U23_08080) - 1579440..1580809 (-) 1370 Protein_1554 bacteriocin secretion accessory protein -
  J7U23_RS08160 (J7U23_08085) - 1580825..1582977 (-) 2153 Protein_1555 peptide cleavage/export ABC transporter -

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30835.17 Da        Isoelectric Point: 4.8309

>NTDB_id=482807 J7U23_RS08145 WP_224103634.1 1578443..1579246(+) (comD/blpH) [Streptococcus thermophilus strain S24736]
MYLENTTHSSTLELRKLCVVISLVLFFIMIVFLERNIREMIQGQLDFQKNLQLENLYTYNKHIECLYNSVRSFRHDYSNL
LVTLRLGIDKDDMDIVKEVYDSVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
EILDFIIVTSIFLDNAIEGAIQTQNHKITISFWEDHRSQLLSISNTISEEQTETKTIFERGVSNKGRERGIGLANVTEIL
DNYINVNLETQSNNFSFTQQLTITKKA

Nucleotide


Download         Length: 804 bp        

>NTDB_id=482807 J7U23_RS08145 WP_224103634.1 1578443..1579246(+) (comD/blpH) [Streptococcus thermophilus strain S24736]
ATGTATCTTGAAAACACTACTCACTCTTCAACTTTGGAGCTTCGAAAACTCTGTGTTGTTATTTCACTTGTCCTCTTCTT
CATTATGATTGTCTTTTTAGAAAGAAACATTCGTGAAATGATTCAAGGACAATTGGACTTCCAGAAAAATCTCCAGCTAG
AGAATCTCTACACCTACAATAAACATATTGAATGTCTCTACAATTCTGTTCGTAGTTTTAGACACGATTATAGTAATCTC
TTAGTCACATTACGATTGGGGATAGATAAAGACGATATGGATATTGTCAAAGAAGTCTATGATAGTGTGCTTCAAGAATC
CGATAAACGATTAAATACAAGAAACTTTGACTTAGCTAGACTCGTTAATATTCAGGATAATACTTTGAAAAGCCTTCTGT
CCGCAAAAGTTTTACAAGCAGAAGAAGAAGGTATTGAAGCTCAGATTAGCATCCCAGAACCCATCCACTTGATTGGGATG
GAGATTCTGGACTTCATTATCGTCACTTCTATTTTTTTAGATAACGCTATTGAAGGTGCCATTCAAACTCAAAACCATAA
AATTACTATTAGCTTTTGGGAAGATCATCGTTCACAGCTATTATCTATTAGCAATACCATAAGTGAAGAACAAACAGAAA
CTAAAACCATATTTGAAAGAGGTGTCTCCAACAAGGGACGAGAGCGAGGCATTGGCCTTGCTAATGTCACAGAAATCTTA
GATAACTATATCAATGTAAACTTAGAAACACAGAGTAACAATTTCTCATTCACACAACAATTAACAATAACTAAAAAGGC
CTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(160-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.189

95.131

0.363