Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   J7U07_RS08840 Genome accession   NZ_CP072433
Coordinates   1698951..1699244 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain S24743     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1693951..1704244
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U07_RS08805 (J7U07_08685) - 1694354..1694797 (-) 444 WP_041829335.1 hypothetical protein -
  J7U07_RS08810 - 1694871..1695296 (-) 426 WP_014608739.1 CPBP family intramembrane glutamic endopeptidase -
  J7U07_RS08815 (J7U07_08695) - 1695539..1695736 (-) 198 WP_014727723.1 helix-turn-helix transcriptional regulator -
  J7U07_RS08820 (J7U07_08700) - 1695985..1697178 (-) 1194 WP_014608740.1 acetate kinase -
  J7U07_RS08825 (J7U07_08705) comGH 1697234..1698190 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  J7U07_RS08830 (J7U07_08710) comGG 1698235..1698552 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG Machinery gene
  J7U07_RS08835 (J7U07_08715) comGF 1698530..1698967 (-) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  J7U07_RS08840 (J7U07_08720) comGE 1698951..1699244 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  J7U07_RS08845 (J7U07_08725) comGD 1699216..1699644 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  J7U07_RS08850 (J7U07_08730) comGC 1699604..1699930 (-) 327 WP_014727724.1 competence type IV pilus major pilin ComGC Machinery gene
  J7U07_RS08855 (J7U07_08735) comGB 1699927..1701027 (-) 1101 WP_372588741.1 competence type IV pilus assembly protein ComGB Machinery gene
  J7U07_RS08860 (J7U07_08740) comGA/cglA/cilD 1700909..1701850 (-) 942 WP_014727726.1 competence type IV pilus ATPase ComGA Machinery gene
  J7U07_RS08865 (J7U07_08745) - 1701931..1702293 (-) 363 WP_014622006.1 DUF1033 family protein -
  J7U07_RS08870 (J7U07_08750) - 1702563..1703812 (+) 1250 Protein_1690 ISL3 family transposase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=482615 J7U07_RS08840 WP_011226625.1 1698951..1699244(-) (comGE) [Streptococcus thermophilus strain S24743]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=482615 J7U07_RS08840 WP_011226625.1 1698951..1699244(-) (comGE) [Streptococcus thermophilus strain S24743]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361