Detailed information NTG0482595

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: J7U07_RS07635
• Genome accession: NZ_CP072433
• Coordinates: 1469253..1471352 (-)
• Length: 699 a.a.
• NCBI ID: WP_372588678.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24743
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1464253..1476352

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U07_RS07600 (J7U07_07495)	pptB	1464719..1465753 (-)	1035	WP_372433575.1	ABC transporter permease	Regulator
J7U07_RS07605 (J7U07_07500)	pptA	1465753..1466484 (-)	732	WP_002951673.1	ABC transporter ATP-binding protein	Regulator
J7U07_RS07610 (J7U07_07505)	-	1466549..1466968 (+)	420	WP_002951675.1	HIT family protein	-
J7U07_RS07615 (J7U07_07510)	-	1466965..1467273 (+)	309	WP_179971427.1	hypothetical protein	-
J7U07_RS07620	-	1467825..1467995 (-)	171	WP_011226439.1	hypothetical protein	-
J7U07_RS07625 (J7U07_07520)	-	1468065..1468700 (-)	636	WP_179971026.1	DUF4230 domain-containing protein	-
J7U07_RS07630	-	1468719..1468844 (-)	126	WP_011681534.1	hypothetical protein	-
J7U07_RS07635 (J7U07_07525)	clpE	1469253..1471352 (-)	2100	WP_372588678.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
J7U07_RS07640 (J7U07_07530)	-	1472067..1473158 (-)	1092	WP_179971027.1	nucleotidyltransferase	-
J7U07_RS07645 (J7U07_07535)	-	1473165..1473905 (-)	741	WP_277426406.1	class I SAM-dependent methyltransferase	-
J7U07_RS07650 (J7U07_07540)	rsfS	1474230..1474583 (-)	354	WP_011227491.1	ribosome silencing factor	-
J7U07_RS07655 (J7U07_07545)	yqeK	1474607..1475197 (-)	591	WP_002951696.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
J7U07_RS07660 (J7U07_07550)	-	1475194..1475826 (-)	633	WP_002951698.1	nicotinate-nucleotide adenylyltransferase	-
J7U07_RS07665 (J7U07_07555)	yhbY	1475930..1476247 (-)	318	WP_002951701.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77199.12 Da
• Isoelectric Point: 4.8564

>NTDB_id=482595 J7U07_RS07635 WP_372588678.1 1469253..1471352(-) (clpE) [Streptococcus thermophilus strain S24743]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLLDVTAAHLAAQHPV
TDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKMTATVNDVAESVERMTGIPVSQMGATDIE
RLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIA
TSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKNAK

Nucleotide

• Length: 2100 bp

>NTDB_id=482595 J7U07_RS07635 WP_372588678.1 1469253..1471352(-) (clpE) [Streptococcus thermophilus strain S24743]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACGCAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAACTTGACT
CAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTAGCGAAATCTTGGCTCG
TCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TCGTTAATGGTGATGTCCCAGCTGCTATCAAGGACAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGCAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCGGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACGTGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGATGACTG
CGACTGTAAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCAACGGATATCGAA
CGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTTTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCTGCTAAA
GCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAAATGCTAAATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (439-599)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (606-676)

• ATPase family associated with various cellular activities (AAA) (AAA) (114-246)

• AAA lid domain (AAA_lid_9) (255-349)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.724	100	0.469
clpC	Lactococcus lactis subsp. cremoris KW2	49.219	91.559	0.451
clpE	Streptococcus pneumoniae Rx1	48.657	90.558	0.441
clpE	Streptococcus pneumoniae R6	48.657	90.558	0.441
clpE	Streptococcus pneumoniae D39	48.657	90.558	0.441
clpE	Streptococcus pneumoniae TIGR4	48.657	90.558	0.441
clpC	Bacillus subtilis subsp. subtilis str. 168	46.13	92.418	0.426
clpC	Streptococcus thermophilus LMD-9	42.969	91.559	0.393
clpC	Streptococcus thermophilus LMG 18311	42.812	91.559	0.392
clpC	Streptococcus pneumoniae TIGR4	43.339	89.127	0.386
clpC	Streptococcus pneumoniae Rx1	43.339	89.127	0.386
clpC	Streptococcus pneumoniae D39	43.339	89.127	0.386
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.274	88.269	0.382
clpC	Streptococcus mutans UA159	42.995	88.841	0.382