Detailed information NTG0482400

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: J7T77_RS07610
• Genome accession: NZ_CP072430
• Coordinates: 1464715..1466820 (-)
• Length: 701 a.a.
• NCBI ID: WP_260214851.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24746
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1459715..1471820

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T77_RS07575 (J7T77_07465)	pptB	1460181..1461215 (-)	1035	WP_372433575.1	ABC transporter permease	Regulator
J7T77_RS07580 (J7T77_07470)	pptA	1461215..1461946 (-)	732	WP_002951673.1	ABC transporter ATP-binding protein	Regulator
J7T77_RS07585 (J7T77_07475)	-	1462011..1462430 (+)	420	WP_002951675.1	HIT family protein	-
J7T77_RS07590 (J7T77_07480)	-	1462427..1462735 (+)	309	WP_179971427.1	hypothetical protein	-
J7T77_RS07595 (J7T77_07485)	-	1463287..1463457 (-)	171	WP_372589656.1	hypothetical protein	-
J7T77_RS07600 (J7T77_07490)	-	1463527..1464162 (-)	636	WP_179971026.1	DUF4230 domain-containing protein	-
J7T77_RS07605	-	1464181..1464306 (-)	126	WP_011681534.1	hypothetical protein	-
J7T77_RS07610 (J7T77_07495)	clpE	1464715..1466820 (-)	2106	WP_260214851.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
J7T77_RS07615 (J7T77_07500)	-	1467535..1468626 (-)	1092	WP_179970587.1	nucleotidyltransferase	-
J7T77_RS07620 (J7T77_07505)	-	1468633..1469373 (-)	741	WP_301280230.1	class I SAM-dependent methyltransferase	-
J7T77_RS07625 (J7T77_07510)	rsfS	1469698..1470051 (-)	354	WP_011227491.1	ribosome silencing factor	-
J7T77_RS07630 (J7T77_07515)	yqeK	1470075..1470665 (-)	591	WP_095559432.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
J7T77_RS07635 (J7T77_07520)	-	1470662..1471294 (-)	633	WP_082309109.1	nicotinate-nucleotide adenylyltransferase	-
J7T77_RS07640 (J7T77_07525)	yhbY	1471398..1471715 (-)	318	WP_002951701.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77328.22 Da
• Isoelectric Point: 4.8235

>NTDB_id=482400 J7T77_RS07610 WP_260214851.1 1464715..1466820(-) (clpE) [Streptococcus thermophilus strain S24746]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQQGNGPKQDGILAKIGRN
LTQEAREGKLDPVIGRNKEIQETSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVSGDVPAAIKDKEIISIDISALEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILK
NPALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLLDVTAAHLAAQH
PVTDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEA
AKAYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKNAK

Nucleotide

• Length: 2106 bp

>NTDB_id=482400 J7T77_RS07610 WP_260214851.1 1464715..1466820(-) (clpE) [Streptococcus thermophilus strain S24746]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACGCAACAACAGGGTAACGGACCTAAACAAGATGGTATTCTTGCTAAAATTGGTCGTAAC
TTGACTCAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTAGCGAAATCTT
GGCTCGTCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCAC
AAGCCATCGTTAGTGGTGATGTCCCAGCTGCTATCAAGGACAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCT
GGTACTCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAACATTATCCT
CTTCTTCGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCT
TGAAACCTGCTCTTTCACGTGGTGAAATAACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAG
AATCCTGCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGG
TATTCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCGGTTGATTTTTCAGTAC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACGTGACAGCAGCTCACTTGGCAGCACAACAT
CCAGTAACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGA
TTACGAAGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGG
TGACTGCGACTGTAAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCAACGGAT
ATCGAACGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACG
TTCCATCCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATAC
CTTGACAGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCA
CCCTTCTCCTCCAAGTTTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATT
ATCGCAACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTT
GAAACCTTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTT
CTAAGATTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAG
TTATCAAAGAAAAAAATGCTAAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (257-351)

• ATPase family associated with various cellular activities (AAA) (AAA) (116-235)

• AAA domain (Cdc48 subfamily) (AAA_2) (441-601)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (608-678)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.449	100	0.466
clpC	Lactococcus lactis subsp. cremoris KW2	48.848	92.867	0.454
clpE	Streptococcus pneumoniae D39	47.975	91.583	0.439
clpE	Streptococcus pneumoniae Rx1	47.975	91.583	0.439
clpE	Streptococcus pneumoniae R6	47.975	91.583	0.439
clpE	Streptococcus pneumoniae TIGR4	47.894	91.441	0.438
clpC	Bacillus subtilis subsp. subtilis str. 168	44.962	94.864	0.427
clpC	Streptococcus thermophilus LMD-9	44.084	88.017	0.388
clpC	Streptococcus thermophilus LMG 18311	43.922	88.017	0.387
clpC	Streptococcus pneumoniae TIGR4	43.339	88.873	0.385
clpC	Streptococcus pneumoniae Rx1	43.339	88.873	0.385
clpC	Streptococcus pneumoniae D39	43.339	88.873	0.385
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.112	88.017	0.379
clpC	Streptococcus mutans UA159	42.834	88.588	0.379