Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   J7T77_RS00340 Genome accession   NZ_CP072430
Coordinates   59617..61560 (+) Length   647 a.a.
NCBI ID   WP_372589681.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24746     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 54617..66560
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7T77_RS00310 (J7T77_00310) argR 54821..55249 (+) 429 WP_024704313.1 arginine repressor -
  J7T77_RS00315 (J7T77_00315) - 55249..55608 (+) 360 WP_011225277.1 YlbF family regulator -
  J7T77_RS00320 (J7T77_00320) hexA 55601..58159 (+) 2559 WP_014607836.1 DNA mismatch repair protein MutS Machinery gene
  J7T77_RS00325 (J7T77_00325) - 58193..58648 (-) 456 Protein_43 DUF3021 domain-containing protein -
  J7T77_RS00330 (J7T77_00330) - 58645..59036 (-) 392 Protein_44 LytTR family DNA-binding domain-containing protein -
  J7T77_RS00335 (J7T77_00335) - 59260..59565 (+) 306 WP_002949050.1 hypothetical protein -
  J7T77_RS00340 (J7T77_00340) hexB 59617..61560 (+) 1944 WP_372589681.1 DNA mismatch repair endonuclease MutL Machinery gene
  J7T77_RS00345 (J7T77_00345) - 61690..61911 (+) 222 WP_002949052.1 hypothetical protein -
  J7T77_RS00350 (J7T77_00350) ruvA 62063..62653 (+) 591 WP_011680603.1 Holliday junction branch migration protein RuvA Machinery gene
  J7T77_RS00355 (J7T77_00355) - 62660..63214 (+) 555 WP_011680604.1 DNA-3-methyladenine glycosylase I -
  J7T77_RS00360 (J7T77_00360) cinA 63310..64581 (+) 1272 WP_011680605.1 competence/damage-inducible protein A Machinery gene
  J7T77_RS00365 (J7T77_00365) recA 64617..65786 (+) 1170 WP_179970786.1 recombinase RecA Machinery gene
  J7T77_RS00370 (J7T77_00370) spx 65963..66361 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72530.85 Da        Isoelectric Point: 6.2614

>NTDB_id=482332 J7T77_RS00340 WP_372589681.1 59617..61560(+) (hexB) [Streptococcus thermophilus strain S24746]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVKESGLSKIQITDNGEGMAQADVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAADGEVYGTKLVAKGGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALIKS
AIAQSLREQDLIPDALENLAKSSTRGATRSVQTSLPLKQTNLYYDSNRNDFFVTPETVQEDIKPLVSKSESSVSLVANKQ
QPTVKQAKRSADDSDSEHGKLDYKNKSKLKRMLENLTNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKY
EYYREKIGVVDSSLQQLLVPYLFEFSGSDYISLQEKMPLLNQVCIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRDLGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=482332 J7T77_RS00340 WP_372589681.1 59617..61560(+) (hexB) [Streptococcus thermophilus strain S24746]
ATGCCAAAAATTATCGAATTGCCTGAAGTTCTAGCCAATCAGATTGCTGCTGGTGAGGTCGTAGAGCGACCAGCTAGTGT
AGTTAAAGAGCTGGTGGAAAATGCTATTGATGCAGGCAGCACCCAGATTACTATTGAAGTTAAAGAATCAGGCCTCTCAA
AAATTCAAATCACAGACAATGGCGAAGGAATGGCTCAAGCTGATGTAGCTATGAGTTTGCGCCGTCATGCAACGAGTAAA
ATCAAAAATCAAGGAGATCTCTTTCGTATTCGAACACTTGGTTTTCGAGGTGAAGCCCTACCCTCTATAGCTTCTATTAG
TCACCTTACCATTGTGACAGCAGCGGATGGAGAAGTCTATGGGACCAAACTTGTTGCTAAAGGTGGAGAAATTGAGAGTC
AAGATCCTATTTCAACCCCAGTGGGAACAAAGATTACAGTTGAAAACTTGTTTTATAACACCCCAGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCTGAGTTGGCTCATATTGTCGATGTTGTCAACCGTTTGAGTTTAGCCCACCCCGAAGTAGCCTT
CACCTTGCTTAATGACGGTCGTCAGTTGACACAGACATCAGGTACTGGAGACCTTCGCCAAGCTATTGCAGGGATTTATG
GCTTAACAACAGCAAAAAAAATGGTGGAAATTTCAAATTCCGACCTTGATTTTGAAGTTTCTGGTTATGTCAGTCTCCCT
GAATTAACGCGTGCTAACCGTAACTACATCACGATTCTCATTAACGGACGCTATATAAAAAACTTCCTCCTTAACCGTGC
TATTTTTGATGGTTATGGTTCTAAACTTATGGTGGGACGCTTCCCAATTGCAGTTATTGATATTCAGATTGATCCTTATT
TGGCAGATGTCAATGTTCACCCAACAAAGCAAGAAGTACGTATCTCTAAAGAAAAGGAGCTCATGGCCCTTATCAAATCT
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATCTAGCAAAGTCAAGTACTAGAGGTGC
AACTAGGTCAGTTCAGACGAGTCTCCCACTCAAACAAACCAATCTTTACTATGACAGTAACCGTAATGATTTCTTTGTCA
CGCCAGAGACAGTTCAAGAGGATATCAAACCTCTTGTATCAAAGTCAGAGTCTTCAGTTTCATTGGTAGCAAACAAACAG
CAACCTACTGTTAAACAGGCAAAACGTTCAGCAGATGATAGTGATAGCGAACACGGAAAACTTGACTATAAAAATAAATC
GAAATTGAAGCGCATGCTTGAAAATCTGACCAATGAGGAAACATCAACCTTTCCTGAATTGGAGTTCTTTGGTCAAATGC
ATGGAACCTACCTCTTTGCCCAAGGACAAGGTGGCCTTTACATCATTGACCAGCATGCTGCCCAAGAACGTGTCAAGTAT
GAGTACTATCGCGAAAAGATAGGTGTGGTTGATAGTAGTTTACAACAACTTTTGGTTCCCTATCTTTTTGAATTTTCAGG
TTCAGATTACATTAGTTTACAAGAAAAAATGCCTCTTCTTAACCAAGTTTGCATCTATTTGGAGCCTTATGGGAATAATA
CCTTCATTCTTCGAGAGCACCCTATCTGGATGAAGGAAGAAGAAATCGAATCTGCAGTCTATGAGATGTGTGATATGCTT
CTTTTGACGAACGAAGTATCCGTCAAGACCTATCGTGCTGAGTTAGCCATCATGATGAGTTGTAAACGTTCAATAAAGGC
CAATCATGCTCTTGATGATTACTCTGCGCGTGACCTTCTAGTACAGCTTGCACAGTGTAAAAATCCCTATAATTGTCCTC
ACGGCCGTCCAGTACTTGTCAACTTTACCAAGTCTGATATGGAAAAAATGTTCCGTCGTATTCAAGAAAACCATACCAGC
CTACGTGATTTAGGAAAGTATTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(448-591)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.266

100

0.7