Detailed information NTG0482300

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: J7T92_RS07705
• Genome accession: NZ_CP072429
• Coordinates: 1469976..1472075 (-)
• Length: 699 a.a.
• NCBI ID: WP_372588845.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24747
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1464976..1477075

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T92_RS07670 (J7T92_07650)	pptA	1465146..1465877 (-)	732	WP_002951673.1	ABC transporter ATP-binding protein	Regulator
J7T92_RS07675 (J7T92_07655)	-	1465942..1466361 (+)	420	WP_372589767.1	HIT family protein	-
J7T92_RS07680 (J7T92_07660)	-	1466358..1466666 (+)	309	WP_014608635.1	hypothetical protein	-
J7T92_RS07685 (J7T92_07665)	-	1466708..1467439 (-)	732	WP_014608636.1	hypothetical protein	-
J7T92_RS07690 (J7T92_07670)	-	1467458..1468093 (-)	636	WP_014727665.1	DUF4230 domain-containing protein	-
J7T92_RS07695	-	1468112..1468237 (-)	126	WP_011681534.1	hypothetical protein	-
J7T92_RS07700 (J7T92_07675)	-	1468418..1469593 (+)	1176	WP_014608082.1	IS256-like element IS1191 family transposase	-
J7T92_RS07705 (J7T92_07680)	clpE	1469976..1472075 (-)	2100	WP_372588845.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
J7T92_RS07710 (J7T92_07685)	-	1472789..1473880 (-)	1092	WP_011681536.1	nucleotidyltransferase	-
J7T92_RS07715 (J7T92_07690)	-	1473887..1474627 (-)	741	WP_277426406.1	class I SAM-dependent methyltransferase	-
J7T92_RS07720 (J7T92_07695)	rsfS	1474952..1475305 (-)	354	WP_011227491.1	ribosome silencing factor	-
J7T92_RS07725 (J7T92_07700)	yqeK	1475329..1475919 (-)	591	WP_002951696.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
J7T92_RS07730 (J7T92_07705)	-	1475916..1476548 (-)	633	WP_002951698.1	nicotinate-nucleotide adenylyltransferase	-
J7T92_RS07735 (J7T92_07710)	yhbY	1476652..1476969 (-)	318	WP_002951701.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77212.16 Da
• Isoelectric Point: 4.8280

>NTDB_id=482300 J7T92_RS07705 WP_372588845.1 1469976..1472075(-) (clpE) [Streptococcus thermophilus strain S24747]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDEVLKAAVDFSVQYIPQRSLPDKAIDLLDMTAAHLAAQHPV
TDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGASDIE
RLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIA
TSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMIEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide

• Length: 2100 bp

>NTDB_id=482300 J7T92_RS07705 WP_372588845.1 1469976..1472075(-) (clpE) [Streptococcus thermophilus strain S24747]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACACAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAACTTGACT
CAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTGCCGAAATTTTGTCTCG
TCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TCGTTAATGGTGATGTCCCAGCTGCTATCAAGGATAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTTATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGAAGTCTTGAAAGCAGCGGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACATGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGGTGACTG
CGACTGTAAACGATGTGGCTGAATCCGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCATCGGATATCGAA
CGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTTTTGGATGATGGTCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCTGCTAAA
GCCTATATGATAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCAAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (255-349)

• AAA domain (Cdc48 subfamily) (AAA_2) (439-599)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (606-676)

• ATPase family associated with various cellular activities (AAA) (AAA) (114-246)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.924	100	0.469
clpC	Lactococcus lactis subsp. cremoris KW2	49.219	91.559	0.451
clpE	Streptococcus pneumoniae Rx1	48.657	90.558	0.441
clpE	Streptococcus pneumoniae D39	48.657	90.558	0.441
clpE	Streptococcus pneumoniae R6	48.657	90.558	0.441
clpE	Streptococcus pneumoniae TIGR4	48.576	90.415	0.439
clpC	Bacillus subtilis subsp. subtilis str. 168	45.975	92.418	0.425
clpC	Streptococcus thermophilus LMD-9	43.26	91.273	0.395
clpC	Streptococcus thermophilus LMG 18311	43.103	91.273	0.393
clpC	Streptococcus pneumoniae TIGR4	43.499	89.127	0.388
clpC	Streptococcus pneumoniae Rx1	43.499	89.127	0.388
clpC	Streptococcus pneumoniae D39	43.499	89.127	0.388
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.598	88.269	0.385
clpC	Streptococcus mutans UA159	43.156	88.841	0.383