Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   J7U22_RS01020 Genome accession   NZ_CP072428
Coordinates   198012..198815 (-) Length   267 a.a.
NCBI ID   WP_223899638.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24749     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 193012..203815
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U22_RS01005 (J7U22_01010) - 194283..196435 (+) 2153 Protein_173 peptide cleavage/export ABC transporter -
  J7U22_RS01010 (J7U22_01015) comB 196451..197818 (+) 1368 WP_011681574.1 bacteriocin secretion accessory protein Regulator
  J7U22_RS01015 (J7U22_01020) - 197833..197994 (+) 162 WP_011681573.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  J7U22_RS01020 comD/blpH 198012..198815 (-) 804 WP_223899638.1 ATP-binding protein Regulator
  J7U22_RS01025 (J7U22_01030) - 199346..200083 (-) 738 WP_011681571.1 LytTR family DNA-binding domain-containing protein -
  J7U22_RS01030 (J7U22_01035) - 200334..200510 (+) 177 WP_011681570.1 Blp family class II bacteriocin -
  J7U22_RS01035 (J7U22_01040) - 200529..200729 (+) 201 WP_011681569.1 hypothetical protein -
  J7U22_RS01040 (J7U22_01045) - 201085..201315 (+) 231 WP_260223024.1 bacteriocin class II family protein -
  J7U22_RS01045 - 202302..202703 (+) 402 WP_024703992.1 hypothetical protein -
  J7U22_RS01050 (J7U22_01050) - 202954..203208 (+) 255 WP_014608660.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30641.92 Da        Isoelectric Point: 4.7379

>NTDB_id=482143 J7U22_RS01020 WP_223899638.1 198012..198815(-) (comD/blpH) [Streptococcus thermophilus strain S24749]
MYLENTTHSSTLELRKLCVVISLVLFFIMIVFLDRNIREMIQGQLDFQKNLQLENLYTYNKHIEGLYNSVRSFRHDYSNL
LVTLRLGIDKDDMDIVKEAYDSVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
ETLDFIIVTSIFLDNAIEGAIQTQNPKITISFWEDHCSQLLSISNTISEEKTETKTIFERGVSNKGRERGIGLANVTEIL
DNYINVNLETQSNNFSFTQQLTITKKA

Nucleotide


Download         Length: 804 bp        

>NTDB_id=482143 J7U22_RS01020 WP_223899638.1 198012..198815(-) (comD/blpH) [Streptococcus thermophilus strain S24749]
ATGTATCTTGAAAACACTACTCATTCTTCAACTTTGGAGCTTCGAAAACTCTGTGTTGTTATTTCACTTGTCCTCTTCTT
CATTATGATTGTCTTTTTAGACAGAAACATTCGTGAAATGATTCAAGGACAATTGGACTTCCAAAAAAATCTCCAGCTAG
AAAATCTCTACACCTACAATAAACATATTGAAGGTCTCTACAATTCTGTTCGTAGTTTTAGACACGATTATAGTAATCTC
TTAGTCACATTACGATTGGGGATAGATAAAGACGATATGGATATTGTCAAAGAAGCCTATGATAGTGTGCTTCAAGAATC
CGATAAACGATTAAATACAAGAAACTTTGACTTAGCTAGACTCGTTAATATTCAGGATAACACTTTGAAAAGCCTTCTGT
CCGCAAAAGTTTTACAAGCAGAAGAAGAAGGTATTGAAGCTCAGATTAGCATCCCAGAACCCATCCACTTGATTGGGATG
GAGACTCTGGACTTCATTATCGTCACTTCTATTTTTTTAGATAACGCTATTGAAGGTGCCATTCAAACTCAAAACCCTAA
AATTACTATTAGCTTTTGGGAAGATCATTGTTCACAGCTATTATCTATTAGCAATACCATAAGTGAAGAAAAAACAGAAA
CCAAAACCATATTTGAAAGAGGTGTCTCCAACAAGGGACGAGAGCGAGGCATTGGCCTTGCTAATGTCACAGAAATCTTA
GATAACTATATCAATGTAAACTTAGAAACACAGAGTAACAATTTCTCATTCACACAACAATTAACAATAACTAAAAAGGC
CTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(160-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.189

95.131

0.363