Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | IB937_RS00705 | Genome accession | NZ_CP061132 |
| Coordinates | 109196..110149 (+) | Length | 317 a.a. |
| NCBI ID | WP_021299429.1 | Uniprot ID | A0A660A6K5 |
| Organism | Streptococcus pyogenes strain BSAC_bs1388 isolate Invasive disease | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
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Genomic Context
Location: 104196..115149
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IB937_RS00665 (IB937_00665) | - | 105023..105388 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| IB937_RS00670 (IB937_00670) | comYA | 105481..106419 (+) | 939 | WP_136278207.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| IB937_RS00675 (IB937_00675) | comYB | 106355..107389 (+) | 1035 | WP_011054115.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| IB937_RS00680 (IB937_00680) | comYC | 107391..107717 (+) | 327 | WP_011528161.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| IB937_RS00685 (IB937_00685) | comGD | 107692..108120 (+) | 429 | WP_002986548.1 | competence type IV pilus minor pilin ComGD | - |
| IB937_RS00690 (IB937_00690) | comGE | 108077..108361 (+) | 285 | WP_011528162.1 | competence type IV pilus minor pilin ComGE | - |
| IB937_RS00695 (IB937_00695) | comYF | 108354..108788 (+) | 435 | WP_002992738.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| IB937_RS00700 (IB937_00700) | comGG | 108772..109098 (+) | 327 | WP_010921801.1 | competence type IV pilus minor pilin ComGG | - |
| IB937_RS00705 (IB937_00705) | comYH | 109196..110149 (+) | 954 | WP_021299429.1 | class I SAM-dependent methyltransferase | Machinery gene |
| IB937_RS00710 (IB937_00710) | - | 110208..111404 (+) | 1197 | WP_011528164.1 | acetate kinase | - |
| IB937_RS00715 (IB937_00715) | - | 111591..111899 (+) | 309 | WP_011528165.1 | hypothetical protein | - |
| IB937_RS00720 (IB937_00720) | proC | 111982..112752 (-) | 771 | WP_002986527.1 | pyrroline-5-carboxylate reductase | - |
| IB937_RS00725 (IB937_00725) | pepA | 112800..113867 (-) | 1068 | WP_011528166.1 | glutamyl aminopeptidase | - |
| IB937_RS00730 (IB937_00730) | - | 114332..114616 (+) | 285 | WP_002992749.1 | DUF4651 domain-containing protein | - |
| IB937_RS00735 (IB937_00735) | - | 114613..114930 (+) | 318 | WP_011528167.1 | thioredoxin family protein | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 36043.16 Da Isoelectric Point: 4.7205
>NTDB_id=480851 IB937_RS00705 WP_021299429.1 109196..110149(+) (comYH) [Streptococcus pyogenes strain BSAC_bs1388 isolate Invasive disease]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLVPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLVPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
Nucleotide
Download Length: 954 bp
>NTDB_id=480851 IB937_RS00705 WP_021299429.1 109196..110149(+) (comYH) [Streptococcus pyogenes strain BSAC_bs1388 isolate Invasive disease]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACG
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCTAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACCTGAAAAAAGACGGTTTTGCGATTTTTCTGGTACCAGTCAATTTATTGACAAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACG
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCTAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACCTGAAAAAAGACGGTTTTGCGATTTTTCTGGTACCAGTCAATTTATTGACAAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
65.506 |
99.685 |
0.653 |
| comYH | Streptococcus mutans UA140 |
65.19 |
99.685 |
0.65 |