Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   NMBH4476_RS14860 Genome accession   NC_017516
Coordinates   312600..313064 (+) Length   154 a.a.
NCBI ID   WP_162467382.1    Uniprot ID   -
Organism   Neisseria meningitidis H44/76     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 313790..314458 312600..313064 flank 726


Gene organization within MGE regions


Location: 312600..314458
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMBH4476_RS14860 comE 312600..313064 (+) 465 WP_162467382.1 ComEA family DNA-binding protein Machinery gene
  NMBH4476_RS15030 - 312998..313207 (-) 210 Protein_294 Caudovirus prohead protease -
  NMBH4476_RS15290 - 313228..313686 (+) 459 WP_002234522.1 hypothetical protein -
  NMBH4476_RS01680 (NMBH4476_0300) - 313806..314458 (+) 653 Protein_296 IS1595 family transposase -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16587.88 Da        Isoelectric Point: 10.8645

>NTDB_id=48077 NMBH4476_RS14860 WP_162467382.1 312600..313064(+) (comE) [Neisseria meningitidis H44/76]
MLCPEKMSVMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKAPAKPVLPADKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=48077 NMBH4476_RS14860 WP_162467382.1 312600..313064(+) (comE) [Neisseria meningitidis H44/76]
TTGCTTTGCCCGGAAAAAATGTCGGTGATGGCGGGACGGCATCCGTACGGTGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGACCAGG
CTTCGGTCGGCGCGCCCGCACCAAAAGCCCCAGCCAAACCGGTGCTGCCCGCGGATAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74

Multiple sequence alignment