Detailed information NTG0480274

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: IBL27_RS09055
• Genome accession: NZ_CP061071
• Coordinates: 1840838..1843279 (-)
• Length: 813 a.a.
• NCBI ID: WP_002308265.1
• Uniprot ID: -
• Organism: Streptococcus mutans B04Sm5
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1835838..1848279

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IBL27_RS09040 (IBL27_09040)	rpsJ	1836656..1836964 (-)	309	WP_002262341.1	30S ribosomal protein S10	-
IBL27_RS09045 (IBL27_09045)	-	1837284..1837970 (+)	687	WP_002262342.1	helix-turn-helix domain-containing protein	-
IBL27_RS09050 (IBL27_09050)	-	1838161..1840548 (-)	2388	WP_019806146.1	glycoside hydrolase family 68 protein	-
IBL27_RS09055 (IBL27_09055)	clpC	1840838..1843279 (-)	2442	WP_002308265.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
IBL27_RS09060 (IBL27_09060)	ctsR	1843276..1843740 (-)	465	WP_002262345.1	transcriptional regulator CtsR	-
IBL27_RS09065 (IBL27_09065)	-	1844014..1844376 (+)	363	WP_226707807.1	COG2426 family protein	-
IBL27_RS09070 (IBL27_09070)	-	1844582..1846378 (-)	1797	WP_002277502.1	DHA2 family efflux MFS transporter permease subunit	-
IBL27_RS09075 (IBL27_09075)	-	1846557..1847099 (+)	543	WP_002277501.1	TetR/AcrR family transcriptional regulator	-
IBL27_RS09080 (IBL27_09080)	-	1847241..1847783 (-)	543	WP_002283497.1	TetR/AcrR family transcriptional regulator	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90380.15 Da
• Isoelectric Point: 6.9065

>NTDB_id=480274 IBL27_RS09055 WP_002308265.1 1840838..1843279(-) (clpC) [Streptococcus mutans B04Sm5]
MTDYSLKMQEVFRLAQFEAARFESSYLESWHVLLAMVEIDSSVAGLSFAEFEADVRFEDYQAAAILAIGKKPKSSSNDIM
LLEQSHALKRTLAEAAAISQVTHAKEVGTEHVLFAMLLNPNLLATRILELVGFHAKDDGESIRLLDLRKVIERYAGFSKE
DIKAIFEMRKPKKVKNSSSFSDLMKPPSVTGELADFTRDLTELARQGRLEPVIGREQEISRMVQILSRKTKNNPVLVGDA
GVGKTALAYGFAQRIVDSAVPFELADMKVLELDMMSVVAGTRFRGDFEERMNQIIADIEADGHIVLFIDELHTIMGSGSG
IDSTLDAANILKPALARGSLRTIGATTQEEYQKHIEKDAALSRRFAKVTIEEPSEEEAYQILLGLKKSYETYHHVIISDA
AVMAAVKGAHRYLSSKNLPDSAIDLLDEASATVQGLVKKKAPAYLTDLDHALITNDYQLAKRLLKKEKKPLLKKRAEVKE
EDILATLSKLSGIPVKKLTQADSKKYLNLERELHKRVIGQDDAVSSISRAIRRNQSGIRVGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNILLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKSFSQDYKAMESRILEELKKVYRPEFINRIDEKVVFHN
LGQEDIRHVVKIMVAPLIAHLADQGITLKFQPSALKHLALAGYDAEMGARPLRRTLQTEVEDKLAELILSGKLASGQTLK
IGIQKEKLKFDIV

Nucleotide

• Length: 2442 bp

>NTDB_id=480274 IBL27_RS09055 WP_002308265.1 1840838..1843279(-) (clpC) [Streptococcus mutans B04Sm5]
ATGACCGATTACTCATTAAAAATGCAGGAAGTCTTTCGATTGGCGCAGTTTGAAGCAGCTCGTTTTGAAAGTTCCTATTT
AGAAAGCTGGCATGTCCTTCTTGCAATGGTAGAGATTGATTCCTCAGTGGCTGGTTTAAGTTTTGCGGAATTTGAAGCAG
ATGTCCGTTTTGAGGATTATCAGGCTGCTGCTATTTTGGCGATTGGTAAAAAGCCTAAGTCCTCGAGTAATGATATTATG
CTTTTAGAGCAATCACATGCTTTAAAACGAACCCTAGCAGAGGCCGCTGCTATTAGTCAGGTGACACACGCTAAAGAAGT
CGGCACAGAACATGTTCTCTTTGCTATGTTACTGAATCCTAATCTTTTGGCGACTCGCATTTTAGAATTAGTTGGTTTTC
ACGCCAAAGATGATGGAGAGTCTATCCGTCTTTTGGATCTGCGAAAAGTGATTGAACGTTATGCTGGCTTTTCCAAAGAG
GACATTAAGGCCATCTTTGAAATGCGTAAACCTAAAAAGGTCAAAAATAGCAGCAGCTTTTCTGATTTAATGAAGCCACC
TAGCGTTACAGGTGAACTAGCTGATTTTACACGGGATTTGACGGAGTTGGCAAGACAAGGTCGTTTAGAACCTGTTATTG
GCCGTGAACAAGAAATTTCACGGATGGTTCAAATTTTAAGCCGTAAGACAAAAAATAACCCTGTTTTAGTTGGCGATGCT
GGTGTTGGGAAGACGGCTTTAGCTTATGGATTTGCTCAACGTATTGTGGATAGTGCCGTTCCTTTTGAATTGGCAGATAT
GAAAGTACTAGAGCTCGATATGATGAGTGTTGTTGCAGGAACTCGTTTTCGTGGCGATTTTGAGGAACGAATGAATCAAA
TTATTGCAGACATTGAAGCTGATGGTCACATTGTCCTCTTCATTGATGAGCTGCATACCATTATGGGTTCAGGGAGTGGT
ATTGATAGTACGCTGGATGCTGCTAATATTCTTAAACCAGCTTTAGCGCGCGGCAGTCTTAGAACGATTGGAGCGACTAC
TCAAGAGGAGTATCAAAAGCATATTGAAAAAGATGCTGCTCTTTCTCGCCGTTTTGCTAAGGTAACTATTGAAGAACCAA
GTGAAGAAGAAGCTTATCAGATCTTGCTTGGTTTAAAGAAAAGTTATGAAACTTATCATCATGTTATTATTTCTGATGCA
GCCGTAATGGCGGCAGTCAAAGGAGCACATCGTTATTTAAGTAGTAAAAATTTACCTGATTCGGCTATCGATCTTTTAGA
TGAAGCTAGTGCAACTGTTCAAGGCTTAGTGAAAAAAAAGGCACCAGCTTATTTGACAGATTTAGATCATGCTCTTATCA
CTAACGATTACCAATTAGCTAAGCGTTTGCTGAAAAAGGAGAAGAAGCCTCTACTTAAAAAACGAGCTGAAGTCAAGGAA
GAAGATATCCTAGCTACTCTCAGCAAACTTTCGGGCATCCCTGTCAAAAAATTAACACAGGCTGACAGTAAAAAGTACCT
TAATCTCGAAAGGGAATTACATAAGCGTGTAATTGGTCAAGACGATGCGGTGTCCAGTATCAGCCGTGCTATTCGCCGCA
ATCAATCCGGAATTCGGGTTGGCAAACGTCCCATTGGCTCTTTCATGTTTTTGGGGCCGACAGGTGTTGGTAAAACAGAG
CTTGCTAAGGCTTTGGCAGAAGTGCTTTTTGATGATGAGTCAGCTCTTATTCGTTTTGACATGAGCGAATATATGGAAAA
ATTTGCAGCTTCTCGCCTTAATGGAGCTCCTCCGGGCTATGTGGGGTATGAAGAAGGCGGTGAGTTGACGGAAAAGGTTC
GTAACAAACCTTACTCTGTTCTTCTTTTTGATGAGGTGGAAAAAGCTCATCCAGATATTTTCAATATCTTACTTCAAGTA
CTTGATGATGGTGTTTTGACAGATAGCCGTGGTCGCAAAGTTGATTTTTCAAATACGATTATTATCATGACTTCTAATTT
GGGTGCGACTGCGCTTCGTGATGATAAAACCGTTGGTTTTGGAGCTAAAAGCTTTTCTCAGGATTATAAGGCCATGGAAA
GTCGTATTTTAGAGGAATTAAAAAAGGTTTACCGACCTGAATTTATTAATCGTATTGATGAAAAAGTTGTCTTTCATAAC
CTTGGCCAAGAAGACATACGCCATGTTGTTAAAATTATGGTTGCTCCATTGATTGCCCATTTGGCTGATCAGGGGATTAC
ACTTAAGTTTCAGCCTTCAGCTTTGAAACATTTGGCTCTGGCAGGTTATGATGCTGAAATGGGGGCACGTCCTTTGCGTC
GGACACTTCAGACAGAAGTGGAAGATAAGTTAGCAGAACTTATTCTTTCGGGAAAACTAGCCAGTGGACAGACTCTGAAA
ATAGGTATTCAAAAAGAAAAATTAAAATTTGATATTGTATAA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (105-133)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-55)

• AAA lid domain (AAA_lid_9) (374-461)

• ATPase family associated with various cellular activities (AAA) (AAA) (235-366)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-801)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	99.631	100	0.996
clpC	Streptococcus thermophilus LMD-9	72.426	100	0.727
clpC	Streptococcus thermophilus LMG 18311	72.304	100	0.726
clpC	Streptococcus pneumoniae TIGR4	67.076	100	0.672
clpC	Streptococcus pneumoniae Rx1	67.076	100	0.672
clpC	Streptococcus pneumoniae D39	67.076	100	0.672
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.98	100	0.502
clpC	Bacillus subtilis subsp. subtilis str. 168	43.584	100	0.443
clpE	Streptococcus pneumoniae TIGR4	47.04	76.876	0.362
clpE	Streptococcus pneumoniae Rx1	47.04	76.876	0.362
clpE	Streptococcus pneumoniae D39	47.04	76.876	0.362
clpE	Streptococcus pneumoniae R6	47.04	76.876	0.362
clpE	Streptococcus mutans UA159	46.88	76.876	0.36