Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   IBL27_RS03150 Genome accession   NZ_CP061071
Coordinates   605336..606043 (+) Length   235 a.a.
NCBI ID   WP_002262930.1    Uniprot ID   -
Organism   Streptococcus mutans B04Sm5     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 600336..611043
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IBL27_RS03120 (IBL27_03120) - 600826..601014 (+) 189 WP_002264826.1 DNA-directed RNA polymerase subunit beta -
  IBL27_RS03125 (IBL27_03125) endA 601056..601937 (+) 882 WP_002264825.1 DNA/RNA non-specific endonuclease Machinery gene
  IBL27_RS03130 (IBL27_03130) - 602005..602655 (-) 651 WP_002262934.1 amino acid ABC transporter permease -
  IBL27_RS03135 (IBL27_03135) - 602670..603374 (-) 705 WP_002262933.1 amino acid ABC transporter permease -
  IBL27_RS03140 (IBL27_03140) - 603392..604204 (-) 813 WP_002262932.1 transporter substrate-binding domain-containing protein -
  IBL27_RS03145 (IBL27_03145) - 604201..604983 (-) 783 WP_024784364.1 amino acid ABC transporter ATP-binding protein -
  IBL27_RS03150 (IBL27_03150) vicR 605336..606043 (+) 708 WP_002262930.1 response regulator YycF Regulator
  IBL27_RS03155 (IBL27_03155) vicK 606036..607388 (+) 1353 WP_002264821.1 cell wall metabolism sensor histidine kinase VicK Regulator
  IBL27_RS03160 (IBL27_03160) vicX 607385..608188 (+) 804 WP_002308039.1 MBL fold metallo-hydrolase Regulator
  IBL27_RS03165 (IBL27_03165) rnc 608295..608990 (+) 696 WP_002308038.1 ribonuclease III -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26914.70 Da        Isoelectric Point: 4.8288

>NTDB_id=480241 IBL27_RS03150 WP_002262930.1 605336..606043(+) (vicR) [Streptococcus mutans B04Sm5]
MKKILIVDDEKPISDIIKFNLAKEGYDTITAFDGREALSKYEEENPDLIILDLMLPELDGLEVAKEVRKNSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASGIPEIIIGDLQILPDAFVAKKRGTEVEL
THREFELLHHLATHTGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=480241 IBL27_RS03150 WP_002262930.1 605336..606043(+) (vicR) [Streptococcus mutans B04Sm5]
ATGAAGAAAATTCTAATCGTTGACGATGAAAAACCAATTTCTGATATCATCAAGTTTAACTTGGCTAAGGAAGGTTATGA
CACGATTACAGCCTTTGATGGGCGTGAAGCATTAAGTAAATATGAAGAAGAAAATCCTGACTTGATTATATTGGACTTAA
TGTTACCAGAACTAGACGGTCTTGAAGTGGCTAAGGAAGTTAGAAAAAACAGCCATGTTCCAATTATTATGTTATCAGCT
AAAGACAGTGAGTTTGATAAGGTTATTGGTCTTGAAATTGGTGCTGATGATTATGTGACTAAACCTTTTTCTAATCGTGA
ATTACTGGCGCGTGTAAAAGCGCATCTTCGCCGTACTGAAAATATTGAATCCGCAGTGGCTGAGGAAAATGCTTCAGGTA
TACCTGAAATTATTATTGGGGACTTGCAAATCTTACCAGATGCTTTTGTTGCTAAAAAACGTGGAACAGAGGTAGAGTTA
ACTCACCGTGAGTTTGAGCTGTTGCATCACTTAGCGACACACACAGGTCAGGTGATGACGCGTGAACATTTACTTGAAAC
GGTTTGGGGCTATGATTATTTTGGAGATGTCCGTACTGTTGATGTTACTGTTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCAGAGTACATTTTGACGCGACGCGGTGTTGGTTATTACATGAAATCATATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

100

100

1
  micA Streptococcus pneumoniae Cp1015

78.541

99.149

0.779
  covR Streptococcus salivarius strain HSISS4

45.923

99.149

0.455
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.887

98.298

0.451