Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   NMBM04240196_RS07210 Genome accession   NC_017515
Coordinates   1384531..1385199 (-) Length   222 a.a.
NCBI ID   WP_014581481.1    Uniprot ID   -
Organism   Neisseria meningitidis M04-240196     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1367457..1385199 1384531..1385199 within 0


Gene organization within MGE regions


Location: 1367457..1385199
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMBM04240196_RS07080 (NMBM04240196_1251) - 1367556..1367981 (+) 426 WP_002219430.1 hypothetical protein -
  NMBM04240196_RS07085 (NMBM04240196_1252) - 1368225..1368425 (+) 201 WP_002219431.1 hypothetical protein -
  NMBM04240196_RS07090 (NMBM04240196_1253) - 1368493..1368852 (+) 360 WP_002220694.1 hypothetical protein -
  NMBM04240196_RS07095 (NMBM04240196_1254) - 1368877..1369731 (+) 855 WP_002222642.1 YfdQ family protein -
  NMBM04240196_RS07100 (NMBM04240196_1255) - 1369801..1370016 (+) 216 WP_002222643.1 hypothetical protein -
  NMBM04240196_RS07105 (NMBM04240196_1256) - 1370051..1370311 (+) 261 WP_002223443.1 hypothetical protein -
  NMBM04240196_RS07110 (NMBM04240196_1257) - 1370308..1370601 (+) 294 WP_014581475.1 hypothetical protein -
  NMBM04240196_RS07115 (NMBM04240196_1258) - 1370604..1370795 (+) 192 WP_002219435.1 type ISP restriction/modification enzyme -
  NMBM04240196_RS07120 - 1370795..1370935 (+) 141 WP_002220688.1 hypothetical protein -
  NMBM04240196_RS07125 (NMBM04240196_1259) - 1370932..1371141 (+) 210 WP_002220687.1 hypothetical protein -
  NMBM04240196_RS07130 (NMBM04240196_1260) - 1371199..1372116 (-) 918 WP_002220686.1 KilA-N domain-containing protein -
  NMBM04240196_RS07135 (NMBM04240196_1261) - 1372984..1373463 (-) 480 WP_002241413.1 DUF4760 domain-containing protein -
  NMBM04240196_RS07150 (NMBM04240196_1263) - 1373899..1374279 (-) 381 Protein_1311 type II toxin-antitoxin system PemK/MazF family toxin -
  NMBM04240196_RS07155 (NMBM04240196_1264) - 1374413..1375465 (-) 1053 Protein_1312 integrase arm-type DNA-binding domain-containing protein -
  NMBM04240196_RS07170 (NMBM04240196_1267) yaaA 1375996..1376775 (-) 780 WP_002232311.1 peroxide stress protein YaaA -
  NMBM04240196_RS07175 (NMBM04240196_1268) dapC 1377038..1378225 (-) 1188 WP_014581477.1 succinyldiaminopimelate transaminase -
  NMBM04240196_RS07180 (NMBM04240196_1269) dut 1378301..1378753 (-) 453 WP_014581478.1 dUTP diphosphatase -
  NMBM04240196_RS07185 (NMBM04240196_1270) - 1378896..1379321 (+) 426 Protein_1316 AzlC family ABC transporter permease -
  NMBM04240196_RS07190 (NMBM04240196_1271) pilX 1381890..1382363 (-) 474 WP_002258079.1 PilX family type IV pilin Machinery gene
  NMBM04240196_RS07195 (NMBM04240196_1272) pilK 1382368..1382967 (-) 600 WP_002226439.1 pilus assembly protein Machinery gene
  NMBM04240196_RS07200 (NMBM04240196_1273) pilJ 1382946..1383884 (-) 939 WP_014581479.1 PilW family protein Machinery gene
  NMBM04240196_RS07205 (NMBM04240196_1274) pilV 1383881..1384501 (-) 621 WP_014581480.1 type IV pilus modification protein PilV Machinery gene
  NMBM04240196_RS07210 (NMBM04240196_1275) pilH 1384531..1385199 (-) 669 WP_014581481.1 Tfp pilus assembly protein FimT/FimU Machinery gene

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24890.54 Da        Isoelectric Point: 10.0112

>NTDB_id=48010 NMBM04240196_RS07210 WP_014581481.1 1384531..1385199(-) (pilH) [Neisseria meningitidis M04-240196]
MCTRKQQGFTLTELLIVMVIAAIMAMIALPNMSQWIASRRIASHAERIANLLRFSRGEAVRLNLPVYICPVQVKKDGAPN
NKCDSGKKGQGMLAFGDKNGNKIYDNDTADVLLRSVVLNDDINNKRINYAFNHIAFGQTQPTADRVVWTFNQNGTFGYTK
DQHLTSKSSFFYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCPRNDRRTVCQYK

Nucleotide


Download         Length: 669 bp        

>NTDB_id=48010 NMBM04240196_RS07210 WP_014581481.1 1384531..1385199(-) (pilH) [Neisseria meningitidis M04-240196]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGTCATTGCAGCCATTATGGCGATGAT
AGCCCTCCCCAATATGAGCCAATGGATTGCATCCCGCCGCATTGCCAGTCATGCGGAGCGGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTGCGCCCAAC
AATAAATGTGACTCCGGCAAGAAGGGGCAGGGAATGTTGGCTTTTGGCGATAAGAATGGCAATAAGATATATGACAATGA
TACGGCGGATGTTCTTCTCCGCAGTGTGGTATTGAATGATGATATCAATAATAAGCGGATTAATTATGCCTTCAACCATA
TCGCTTTCGGTCAGACTCAGCCGACCGCTGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATACGAAA
GACCAGCATCTTACAAGCAAATCCAGCTTTTTTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTTGAGGTTTGTCCTAGAAACG
ATAGGCGTACCGTATGCCAATATAAATGA

Domains

Predicted by InterproScan.

Type II transport protein GspH (GspH)

(44-205)

Prokaryotic N-terminal methylation motif (N_methyl)

(4-29)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

85.068

99.55

0.847

Multiple sequence alignment