Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   IBB94_RS01700 Genome accession   NZ_CP061024
Coordinates   315838..317355 (+) Length   505 a.a.
NCBI ID   WP_207559739.1    Uniprot ID   A0A3G6JL13
Organism   Streptococcus thermophilus strain 13498     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 310838..322355
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IBB94_RS09745 - 311118..311288 (+) 171 Protein_280 ascorbate 6-phosphate lactonase -
  IBB94_RS01675 (IBB94_01670) - 311305..311976 (-) 672 WP_002946492.1 TrkA family potassium uptake protein -
  IBB94_RS01680 (IBB94_01675) - 312016..313380 (-) 1365 WP_269149496.1 potassium transporter TrkG -
  IBB94_RS01685 (IBB94_01680) rsmG 313450..314163 (-) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  IBB94_RS01690 (IBB94_01685) - 314460..314996 (+) 537 WP_002946488.1 YceD family protein -
  IBB94_RS01695 (IBB94_01690) covR 315152..315841 (+) 690 WP_002949638.1 response regulator transcription factor Regulator
  IBB94_RS01700 (IBB94_01695) covS 315838..317355 (+) 1518 WP_207559739.1 HAMP domain-containing histidine kinase Regulator
  IBB94_RS01705 (IBB94_01700) nrdR 317477..317956 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  IBB94_RS01710 (IBB94_01705) - 317953..319128 (+) 1176 WP_002949643.1 DnaD domain protein -
  IBB94_RS01715 (IBB94_01710) dnaI 319132..320034 (+) 903 WP_002946786.1 primosomal protein DnaI -
  IBB94_RS01720 (IBB94_01715) der 320140..321450 (+) 1311 WP_179970760.1 ribosome biogenesis GTPase Der -
  IBB94_RS01725 (IBB94_01720) - 321514..322182 (+) 669 Protein_291 HI_0552 family protein -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57557.99 Da        Isoelectric Point: 5.5179

>NTDB_id=479747 IBB94_RS01700 WP_207559739.1 315838..317355(+) (covS) [Streptococcus thermophilus strain 13498]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSSEPLLAAFY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLKFYYALKERLIFLLIFLEVGMTVLVIAVIVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGALALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=479747 IBB94_RS01700 WP_207559739.1 315838..317355(+) (covS) [Streptococcus thermophilus strain 13498]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTTCAGAGCCGCTTTTAGCGGCCTTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGAAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAATTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACAATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGCTTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTCCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGGTTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

ArlS sensor domain (ArlS_N)

(39-187)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3G6JL13

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.024

99.406

0.935