Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   NMBM01240149_RS06875 Genome accession   NC_017514
Coordinates   1345483..1346151 (-) Length   222 a.a.
NCBI ID   WP_014582407.1    Uniprot ID   -
Organism   Neisseria meningitidis M01-240149     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1331565..1346151 1345483..1346151 within 0


Gene organization within MGE regions


Location: 1331565..1346151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMBM01240149_RS06755 (NMBM01240149_1179) - 1331565..1331765 (+) 201 WP_002219431.1 hypothetical protein -
  NMBM01240149_RS06760 (NMBM01240149_1180) - 1331833..1332192 (+) 360 WP_002219432.1 hypothetical protein -
  NMBM01240149_RS06765 (NMBM01240149_1181) - 1332217..1333071 (+) 855 WP_002219433.1 YfdQ family protein -
  NMBM01240149_RS06770 (NMBM01240149_1182) - 1333141..1333356 (+) 216 WP_002219434.1 hypothetical protein -
  NMBM01240149_RS06775 (NMBM01240149_1183) - 1333391..1333651 (+) 261 WP_002223443.1 NGO1622 family putative holin -
  NMBM01240149_RS06780 (NMBM01240149_1184) - 1333648..1333941 (+) 294 WP_002241415.1 hypothetical protein -
  NMBM01240149_RS06785 (NMBM01240149_1185) - 1333944..1334135 (+) 192 WP_002219435.1 type ISP restriction/modification enzyme -
  NMBM01240149_RS06790 (NMBM01240149_1186) - 1334135..1334275 (+) 141 WP_002220688.1 hypothetical protein -
  NMBM01240149_RS06795 (NMBM01240149_1187) - 1334272..1334481 (+) 210 WP_002220687.1 hypothetical protein -
  NMBM01240149_RS06800 (NMBM01240149_1188) - 1334539..1335456 (-) 918 WP_002241414.1 KilA-N domain-containing protein -
  NMBM01240149_RS06805 (NMBM01240149_1189) - 1336325..1336804 (-) 480 WP_002241413.1 DUF4760 domain-containing protein -
  NMBM01240149_RS06820 (NMBM01240149_1191) - 1337240..1337620 (-) 381 WP_002220683.1 type II toxin-antitoxin system PemK/MazF family toxin -
  NMBM01240149_RS06825 (NMBM01240149_1192) - 1337777..1338973 (-) 1197 WP_014581123.1 tyrosine-type recombinase/integrase -
  NMBM01240149_RS06840 (NMBM01240149_1195) yaaA 1339504..1340283 (-) 780 WP_002222649.1 peroxide stress protein YaaA -
  NMBM01240149_RS15840 - 1340332..1340457 (-) 126 Protein_1250 IS5/IS1182 family transposase -
  NMBM01240149_RS06845 (NMBM01240149_1196) dapC 1340545..1341732 (-) 1188 WP_002222650.1 succinyldiaminopimelate transaminase -
  NMBM01240149_RS06850 (NMBM01240149_1197) dut 1341809..1342261 (-) 453 WP_002229326.1 dUTP diphosphatase -
  NMBM01240149_RS06855 (NMBM01240149_1198) pilX 1342824..1343297 (-) 474 WP_014581124.1 PilX family type IV pilin Machinery gene
  NMBM01240149_RS06860 (NMBM01240149_1199) pilK 1343302..1343895 (-) 594 WP_014581125.1 pilus assembly PilX family protein Machinery gene
  NMBM01240149_RS06865 (NMBM01240149_1200) pilJ 1343874..1344842 (-) 969 WP_014582408.1 PilW family protein Machinery gene
  NMBM01240149_RS06870 (NMBM01240149_1201) pilV 1344839..1345453 (-) 615 WP_014581127.1 type IV pilus modification protein PilV Machinery gene
  NMBM01240149_RS06875 (NMBM01240149_1202) pilH 1345483..1346151 (-) 669 WP_014582407.1 GspH/FimT family pseudopilin Machinery gene

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24939.52 Da        Isoelectric Point: 9.7404

>NTDB_id=47963 NMBM01240149_RS06875 WP_014582407.1 1345483..1346151(-) (pilH) [Neisseria meningitidis M01-240149]
MCTRKQQGFTLTELLIVMVIAAIMAMIALPNMSQWIASRRIASHAERIANLLRFSRGEAVRLNLPVYICPVQVKKDGTVN
NKCDSGKKGQGMLAFGDKNGNKGYDNDTADVLLRSVVLNDDINDKRINYAFNHIAFGQTQPTTDRVVWTFNQNGTFGYTK
DQHLTKQSSFFYSDGYIQIVLTDARAVSDADKKFRSAVVLIDSSGRVEVCPRNDRRTVCQYK

Nucleotide


Download         Length: 669 bp        

>NTDB_id=47963 NMBM01240149_RS06875 WP_014582407.1 1345483..1346151(-) (pilH) [Neisseria meningitidis M01-240149]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGTCATTGCAGCCATTATGGCGATGAT
AGCCCTCCCCAATATGAGCCAATGGATTGCATCCCGCCGCATTGCCAGTCACGCGGAGCGGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTACGGTCAAC
AATAAATGTGACTCCGGCAAGAAGGGGCAGGGAATGTTGGCTTTCGGCGACAAAAACGGCAATAAGGGATATGACAATGA
TACGGCGGATGTTCTCCTCCGCAGTGTGGTATTGAATGATGATATCAATGATAAGCGGATTAATTATGCCTTCAACCATA
TCGCTTTTGGTCAGACTCAGCCGACCACCGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATACGAAA
GACCAGCATCTTACAAAACAATCCAGCTTTTTTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTTGAGGTTTGTCCTAGAAACG
ATAGGCGTACCGTATGCCAATATAAATGA

Domains

Predicted by InterproScan.

Type II transport protein GspH (GspH)

(44-205)

Prokaryotic N-terminal methylation motif (N_methyl)

(4-29)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

83.71

99.55

0.833

Multiple sequence alignment