Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   IBC33_RS10390 Genome accession   NZ_CP061006
Coordinates   2069197..2070993 (+) Length   598 a.a.
NCBI ID   WP_126708969.1    Uniprot ID   -
Organism   Lactobacillus crispatus strain lc31     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 2067773..2075577 2069197..2070993 within 0


Gene organization within MGE regions


Location: 2067773..2075577
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IBC33_RS10385 - 2067773..2068951 (-) 1179 WP_005727505.1 IS256 family transposase -
  IBC33_RS10390 pepF 2069197..2070993 (+) 1797 WP_126708969.1 oligoendopeptidase F Regulator
  IBC33_RS10395 - 2071145..2071360 (+) 216 WP_005723825.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
  IBC33_RS10400 - 2071364..2071771 (+) 408 WP_005723824.1 type II toxin-antitoxin system death-on-curing family toxin -
  IBC33_RS10405 - 2071885..2072160 (-) 276 WP_005723823.1 bacteriocin immunity protein -
  IBC33_RS10410 - 2072164..2072382 (-) 219 WP_005726358.1 TIGR04139 family peptide modification target -
  IBC33_RS10415 - 2072556..2072852 (-) 297 WP_005725464.1 bacteriocin immunity protein -
  IBC33_RS10420 - 2072868..2073128 (-) 261 WP_005727422.1 thioredoxin domain-containing protein -
  IBC33_RS10425 - 2073316..2074494 (+) 1179 WP_005727388.1 IS256 family transposase -
  IBC33_RS10430 - 2074720..2075577 (+) 858 WP_005728089.1 IS982-like element ISLh1 family transposase -

Sequence

Protein


Download         Length: 598 a.a.        Molecular weight: 67943.77 Da        Isoelectric Point: 4.6935

>NTDB_id=479424 IBC33_RS10390 WP_126708969.1 2069197..2070993(+) (pepF) [Lactobacillus crispatus strain lc31]
MAIPTRNEVPEELKWDLTRIFKNDDEWEQAYAAAQEKVAKLAELKGTLAKSGKNLYESLTKILAVKRDVENIYVYATMSS
DVDTSNSHYLGYVSRVQSLANQFEAATSFINPEILSIPSDKLEQFKQAEPRLKDYAHYLETITNKRPHTLPAEQEKLIAD
AGDALSVSENTFNVLTNSDMEYGYVQDDDGNMEQLSDGLYSLLIQSQNRDVRKGAFDTLYATYGQFQNSLASTLSGVVKK
HNYNARVHKYNSAREAALADNGVPVAVYDTLIQEVDSHLDLLHRYVALRKKILGLKDLQMWDMYVPLTGRPSLSYNFEEA
KETAKKALAPLGEDYLKHVDYIFNNRVIDPIESKNKVTGAYSGGAYDTDPYELLNWEDNIDSLYTLVHETGHSVHSWYTR
NTQPYVYGDYPIFVAEIASTTNENILTEYFLDHITDPKTRAFILNYSLDSFKGTLFRQTQFAVFEQFLHEADAKGEPLTA
DTLDDVYGQINQHYYGDSVEPGGDIALEWSRIPHFYYNFYVYQYATGFAAATALANKVVHGTPAERDAYLGFLKAGSSDY
PTEIMKRAGVDMTKPDYLEDAFKTFEKRLNEFESLIEK

Nucleotide


Download         Length: 1797 bp        

>NTDB_id=479424 IBC33_RS10390 WP_126708969.1 2069197..2070993(+) (pepF) [Lactobacillus crispatus strain lc31]
ATGGCAATTCCAACTAGAAACGAAGTCCCTGAAGAGCTTAAATGGGACTTAACCCGTATTTTTAAAAATGACGATGAATG
GGAGCAAGCTTATGCAGCTGCACAAGAAAAAGTGGCTAAACTTGCTGAATTAAAAGGTACACTAGCTAAATCAGGCAAGA
ACCTGTACGAGAGCTTAACCAAAATCTTAGCTGTTAAACGTGATGTGGAAAATATCTACGTTTACGCTACCATGTCCAGC
GATGTTGATACTTCTAATTCGCACTATCTCGGCTACGTCAGCCGGGTACAAAGTTTGGCTAACCAGTTTGAGGCTGCAAC
AAGTTTTATTAATCCTGAAATCTTGAGTATCCCTAGTGATAAGCTTGAGCAATTTAAGCAAGCTGAACCTAGATTAAAGG
ATTACGCACACTATCTTGAAACAATTACTAACAAGCGTCCTCATACATTACCTGCTGAGCAAGAAAAATTGATCGCCGAT
GCTGGGGATGCTTTAAGTGTTTCTGAAAATACCTTTAACGTTTTGACCAACTCCGACATGGAATACGGTTACGTTCAAGA
CGATGACGGCAATATGGAACAATTATCAGATGGCCTTTATTCTTTGCTGATCCAATCCCAAAATCGTGATGTCAGAAAAG
GTGCTTTTGATACACTTTATGCCACTTATGGACAGTTCCAAAATTCCTTGGCTTCAACTTTGTCTGGCGTTGTAAAAAAG
CACAACTATAACGCACGTGTGCACAAGTATAATTCAGCTCGTGAAGCTGCTTTAGCCGATAATGGCGTACCCGTAGCAGT
TTATGACACTTTAATCCAGGAAGTTGATTCACACCTAGACTTACTTCACCGTTATGTTGCGCTACGTAAAAAGATCTTAG
GCCTGAAGGATCTGCAAATGTGGGACATGTATGTGCCACTAACCGGAAGACCTTCTCTTTCATACAATTTCGAAGAAGCA
AAAGAGACAGCAAAAAAGGCTTTGGCTCCACTTGGTGAAGACTACTTGAAGCATGTTGACTATATTTTTAATAATCGTGT
CATCGACCCAATAGAATCTAAAAACAAGGTAACTGGTGCCTACTCCGGTGGTGCTTATGATACCGATCCTTATGAGTTGC
TCAACTGGGAAGATAACATCGATTCACTTTATACTTTAGTCCACGAAACTGGTCACTCCGTTCACTCCTGGTACACTCGC
AATACTCAACCTTACGTTTACGGCGACTATCCAATCTTTGTGGCTGAAATTGCTTCAACTACTAATGAAAATATTTTGAC
CGAATATTTCTTAGACCACATTACCGATCCTAAGACGCGGGCCTTTATCTTAAATTACTCCCTTGATTCATTTAAAGGCA
CTTTATTCCGTCAAACTCAATTTGCCGTGTTTGAACAATTCTTGCACGAAGCCGATGCTAAGGGAGAACCACTGACCGCT
GACACTTTAGACGACGTTTACGGTCAAATTAATCAGCATTATTACGGCGATAGCGTTGAACCAGGCGGCGATATTGCCCT
TGAATGGTCACGAATTCCACACTTCTACTACAATTTCTATGTGTACCAATATGCGACTGGCTTTGCGGCTGCAACGGCAT
TAGCAAACAAGGTGGTTCATGGAACGCCTGCTGAGAGGGATGCCTACCTTGGTTTCCTTAAAGCTGGTTCAAGTGATTAC
CCAACTGAGATCATGAAGCGTGCTGGCGTAGACATGACTAAGCCTGACTACTTAGAAGATGCCTTCAAGACTTTTGAAAA
ACGGTTGAACGAATTTGAAAGCTTGATTGAGAAATAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(113-181)

Peptidase family M3 (Peptidase_M3)

(203-583)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

51.433

99.164

0.51