Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   H9Q12_RS06180 Genome accession   NZ_CP060700
Coordinates   1261448..1262164 (+) Length   238 a.a.
NCBI ID   WP_014613411.1    Uniprot ID   X2JA42
Organism   Staphylococcus pseudintermedius strain Z0118SP0130     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1256448..1267164
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H9Q12_RS06155 - 1257854..1258657 (+) 804 WP_101458021.1 carbon-nitrogen family hydrolase -
  H9Q12_RS13165 - 1258941..1259021 (-) 81 WP_110144734.1 delta-lysin family phenol-soluble modulin -
  H9Q12_RS06165 - 1259413..1259979 (+) 567 WP_014613414.1 accessory gene regulator AgrB -
  H9Q12_RS06170 agrD 1259981..1260118 (+) 138 WP_014613413.1 cyclic lactone autoinducer peptide AgrD -
  H9Q12_RS06175 agrC 1260142..1261434 (+) 1293 WP_015729415.1 quorum-sensing sensor histidine kinase AgrC -
  H9Q12_RS06180 agrA 1261448..1262164 (+) 717 WP_014613411.1 quorum-sensing response regulator AgrA Regulator
  H9Q12_RS06185 - 1262224..1263168 (-) 945 WP_063278587.1 carbohydrate kinase family protein -
  H9Q12_RS06190 - 1263172..1264656 (-) 1485 WP_187470855.1 sucrose-6-phosphate hydrolase -
  H9Q12_RS06195 - 1264712..1265659 (-) 948 WP_187470856.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 28002.15 Da        Isoelectric Point: 5.4331

>NTDB_id=477798 H9Q12_RS06180 WP_014613411.1 1261448..1262164(+) (agrA) [Staphylococcus pseudintermedius strain Z0118SP0130]
MKILICEDDPKQRERMVSIIENYIMIEEKPMKIELATNDPYAILETSKNMTDIGCYFLDIQLESDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPEELRTRIIDCLETALKRLDLLTKDHTVETLELKRGTSSVYVNYDDVM
FFESSPKSHRLIAHLDNRQIEFYGNLKELAQLDDRFFRCHNSYVLNRRNITSVDTKERIAYFKNEEFCYVSVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=477798 H9Q12_RS06180 WP_014613411.1 1261448..1262164(+) (agrA) [Staphylococcus pseudintermedius strain Z0118SP0130]
ATGAAAATTTTGATTTGTGAGGATGATCCTAAACAACGCGAACGTATGGTGTCCATTATTGAAAACTATATTATGATTGA
AGAGAAGCCGATGAAAATTGAGCTTGCTACCAATGACCCTTATGCTATCTTAGAAACTTCTAAAAACATGACTGATATTG
GCTGCTACTTTTTAGATATTCAATTAGAGTCTGATATTAACGGGATTAAATTAGGGAGCGAAATTCGTAAGCACGATCCT
GTTGGGAATATTATTTTTGTGACGAGTCATAGTGAGCTGACGTACTTGACTTTTGTCTATAAAGTGGCTGCCATGGATTT
TATTTTTAAAGATGATCCTGAAGAATTAAGGACACGCATTATCGATTGTTTAGAAACAGCATTAAAACGGCTTGATTTAT
TAACAAAAGATCATACTGTTGAAACTTTGGAACTCAAACGTGGAACCAGCTCGGTTTACGTGAACTATGACGACGTGATG
TTTTTCGAGTCCTCACCGAAGTCACATCGTTTAATCGCGCATTTAGACAATCGTCAAATCGAATTTTACGGCAATTTGAA
AGAGTTAGCTCAACTCGATGATCGATTCTTCAGATGCCACAACAGTTATGTGCTAAACAGAAGAAATATTACAAGTGTCG
ATACGAAAGAACGGATTGCTTATTTCAAAAATGAAGAATTTTGTTACGTGTCGGTGCGTAATTTGAAGAAAATTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(152-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB X2JA42

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

83.193

100

0.832