Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   NMV_RS10000 Genome accession   NC_017501
Coordinates   1952695..1955772 (+) Length   1025 a.a.
NCBI ID   WP_014574221.1    Uniprot ID   A0A9K2KQR0
Organism   Neisseria meningitidis 8013     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1947695..1960772
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMV_RS09965 (NMV_2031) murU 1947857..1948552 (-) 696 WP_002236482.1 N-acetylmuramate alpha-1-phosphate uridylyltransferase MurU -
  NMV_RS09970 (NMV_2032) hpaC 1948568..1949068 (-) 501 WP_002236418.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
  NMV_RS09975 (NMV_2033) nadR 1949183..1949623 (-) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  NMV_RS09985 (NMV_2034) - 1949966..1950475 (-) 510 WP_002236419.1 protein disulfide oxidoreductase -
  NMV_RS09995 (NMV_2036) apbC 1950840..1951919 (+) 1080 WP_014574220.1 iron-sulfur cluster carrier protein ApbC -
  NMV_RS10000 (NMV_2037) pilC 1952695..1955772 (+) 3078 WP_014574221.1 PilC family type IV pilus tip adhesin Machinery gene
  NMV_RS15240 - 1957417..1957770 (-) 354 WP_158303450.1 hypothetical protein -
  NMV_RS10010 (NMV_2040) carA 1958040..1959173 (+) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  NMV_RS10015 (NMV_2041) - 1959219..1959356 (+) 138 WP_002214606.1 VOC family protein -
  NMV_RS10020 (NMV_2042) - 1959918..1960307 (+) 390 WP_002219820.1 endonuclease domain-containing protein -

Sequence

Protein


Download         Length: 1025 a.a.        Molecular weight: 112132.07 Da        Isoelectric Point: 9.8158

>NTDB_id=47759 NMV_RS10000 WP_014574221.1 1952695..1955772(+) (pilC) [Neisseria meningitidis 8013]
MNKTLKRQVFRHTALYAAILMFSHTGGGGAQAQTSKYAIIMNERNQLEVKQEGSYSTLREKDRERKFDFNANRGGGGSVF
FDNTDTLVSRQSGTAVFGTATYLPPYGKVSGFDADGLNKRGNAAGWIRTTRIALAGYSYKGVVCRSGTGCPKLVYKTRFS
FDNPDLVKNAGRLDRHTDPSRENSPIYKLKDYPWLGVSFNLGAEGTTKDGKTINKLVSSFDEKNSSNNNLVYTTEGRDIS
LGDWQREKTAMAYYLNAKLHLLDKKGIKDITNKTVQLGVLRPSIDVRLQRNTGLTGLLNFWASWDIKDNGQIPVKLGLPE
VKAGRCINANNPNKSTKAPSPALTAPALWFGPVQNGKMEMYSASVSTYPDSSSSRIFLQNLKRKNDPNKPGRYSLATLNK
SDIESREPTFTGRQTVIRLDKGVHQIKLKGNEVEGFKGNNGNDTFGIVSEGSFMPDDSEWKKVLLPWTVRGSADDNRFKS
INQESSKYSQRYRIRDNNGNRNLGDIVNSPIVAVGEYLATSANDGMVHIFKKNGGGDDRNYSLKLSYIPGTMPRKDIQNT
ESTLAKELRTFAEKGYVGDRYGVDGGFVLREVELSGKKHVFMFGAMGFGGRGAYALDLTKADSNNPTAVSLFDVKNDKNS
NNGVQLGYTVGTPQIGKTHDGKYAAFLASGYATKEITSNDNKTALYVYDLESNGTLIKKIEVPGGKGGLSSPTLVDKDLD
GTVDIAYAGDRGGKMYRFDLSGNNLNSWTVRTIFEGTKPITSAPAISQLKDKRVVIFGTGSDLSEDDVDNNDMQSIYGIF
DNDTDTGVAKDGQGNGLLEQVLSEENKTLFLTDYKRSDGSGSKGWVVKLKEGQRVTVKPTVVLRTAFVTIHKYTGTDKCG
AETAILGINTADGGKLTKKSARPIVPAANTAVAQYSGHKQTAKGKSIPIGCMWKNNETVCPNGYVYDKPVNVRYLDEKKT
DGFSTTADGDAGGSGIDPDGKRAGKNNRCFSQKGVRTLLMNDLDSLDITGPTCGMKRISWREVFF

Nucleotide


Download         Length: 3078 bp        

>NTDB_id=47759 NMV_RS10000 WP_014574221.1 1952695..1955772(+) (pilC) [Neisseria meningitidis 8013]
ATGAATAAAACTTTAAAAAGGCAGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGCAGGCGCAAACCAGTAAATACGCTATTATCATGAACGAACGAAATCAGCTGGAGGTAAAGCAGGAGGGTT
CATATTCAACCTTAAGGGAAAAAGACAGGGAACGCAAATTTGACTTTAATGCGAACAGAGGGGGTGGAGGTTCTGTCTTT
TTCGACAATACCGATACCCTTGTTTCCCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGG
CAAGGTTTCCGGTTTTGATGCCGACGGGCTGAACAAGCGCGGCAATGCCGCCGGTTGGATTCGTACCACCCGCATCGCGC
TGGCAGGCTACAGCTACAAAGGTGTCGTATGCAGAAGCGGCACAGGCTGTCCCAAACTTGTCTATAAAACCCGATTTTCC
TTCGATAATCCCGACTTGGTAAAAAATGCGGGCAGGCTGGATAGGCACACAGACCCAAGCCGCGAAAATTCGCCCATTTA
CAAATTGAAGGATTATCCATGGTTGGGCGTATCTTTCAATTTGGGTGCCGAGGGTACCACCAAAGATGGTAAGACAATCA
ACAAATTGGTATCTTCTTTTGATGAAAAGAATAGTAGTAATAACAACCTCGTCTATACCACGGAAGGCCGCGATATTTCC
TTGGGCGACTGGCAGCGCGAAAAGACCGCCATGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGACAAAAAAGGGAT
TAAAGATATCACCAACAAAACAGTGCAGTTGGGTGTCTTGAGGCCGAGCATCGATGTGCGGCTGCAAAGAAATACGGGGC
TTACCGGCTTGCTAAATTTTTGGGCTAGTTGGGACATTAAAGATAACGGGCAGATTCCGGTCAAGCTCGGCCTGCCGGAA
GTCAAAGCAGGCCGCTGCATCAACGCAAATAACCCCAATAAGAGTACCAAAGCCCCTTCCCCCGCACTGACTGCCCCCGC
GCTGTGGTTCGGACCTGTGCAAAATGGTAAGATGGAGATGTATTCCGCTTCGGTTTCTACCTACCCCGACAGTTCGAGCA
GCCGCATCTTCCTTCAAAATCTGAAAAGAAAAAACGACCCCAACAAACCCGGCCGCTATTCCCTCGCAACCTTGAATAAG
TCGGATATTGAAAGTCGAGAGCCGACTTTCACAGGGCGGCAAACCGTCATCCGATTGGATAAAGGCGTACATCAGATCAA
ACTTAAAGGCAATGAGGTCGAAGGTTTTAAGGGAAACAACGGCAACGACACTTTCGGCATTGTTAGTGAAGGGAGCTTCA
TGCCTGATGACAGCGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTTCTGCTGATGACAATCGATTTAAATCA
ATTAACCAAGAATCAAGCAAATACAGCCAAAGATACCGCATCCGCGACAACAACGGCAATCGCAATTTGGGCGACATCGT
CAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCAAAAAAAACG
GCGGCGGGGATGACCGCAACTATAGTCTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCAAGGATATTCAAAACACC
GAATCCACCCTTGCCAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTT
TGTCTTGCGCGAAGTCGAACTGAGCGGGAAAAAACACGTGTTTATGTTCGGCGCGATGGGCTTTGGCGGCAGAGGCGCGT
ATGCCTTGGATTTGACCAAAGCCGACAGCAATAACCCGACCGCCGTTTCCCTGTTTGATGTCAAAAATGACAAGAATAGC
AATAACGGCGTGCAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCACGACGGCAAATACGCCGCCTTCCT
CGCCTCCGGTTATGCGACTAAAGAGATTACCAGCAACGATAATAAAACCGCGCTGTATGTGTATGATTTGGAAAGCAACG
GTACGCTGATTAAAAAAATCGAAGTACCCGGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGAC
GGCACGGTCGATATCGCCTATGCCGGCGATCGCGGCGGCAAGATGTACCGCTTTGATTTAAGCGGCAACAACCTGAACAG
TTGGACTGTACGCACTATTTTTGAAGGCACAAAACCGATTACTTCCGCGCCTGCTATTTCCCAACTGAAAGACAAACGCG
TGGTCATCTTCGGCACGGGCAGTGATTTGAGTGAAGATGATGTTGATAATAATGATATGCAATCTATTTACGGTATTTTT
GACAATGACACAGACACAGGTGTGGCGAAAGACGGGCAGGGCAACGGGCTGCTCGAGCAAGTGCTTAGTGAGGAAAATAA
AACCTTATTCCTGACCGATTATAAGCGATCCGACGGATCGGGCAGTAAGGGGTGGGTAGTGAAGCTGAAGGAAGGACAGC
GCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCATAAATATACGGGTACGGACAAATGCGGC
GCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCCGATTGTGCCGGC
AGCCAATACGGCTGTCGCGCAATATTCCGGCCATAAGCAAACCGCCAAAGGCAAATCCATCCCTATAGGTTGTATGTGGA
AAAACAATGAAACCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGTTATCTGGATGAAAAGAAAACA
GACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGACGGCAAGCGTGCCGGCAAAAACAA
CCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGACATTACCGGCCCGACGTGCG
GTATGAAACGAATCAGCTGGCGTGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(503-832)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

79.215

100

0.807

Multiple sequence alignment