Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   H7786_RS06405 Genome accession   NZ_CP060649
Coordinates   1273311..1274348 (-) Length   345 a.a.
NCBI ID   WP_002983824.1    Uniprot ID   A0A4U9C0Q7
Organism   Streptococcus pyogenes strain TSPY270     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1268311..1279348
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7786_RS06385 (H7786_06440) - 1269060..1269686 (+) 627 WP_030126387.1 prepilin peptidase -
  H7786_RS06390 (H7786_06445) rlmN 1269768..1270847 (-) 1080 WP_030126386.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  H7786_RS06395 (H7786_06450) - 1270851..1271471 (-) 621 WP_002992791.1 YutD family protein -
  H7786_RS06400 (H7786_06455) - 1271919..1272896 (-) 978 WP_002994809.1 LacI family DNA-binding transcriptional regulator -
  H7786_RS06405 (H7786_06460) sepM 1273311..1274348 (-) 1038 WP_002983824.1 SepM family pheromone-processing serine protease Regulator
  H7786_RS06410 (H7786_06465) coaD 1274335..1274826 (-) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  H7786_RS06415 (H7786_06470) rsmD 1274816..1275355 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  H7786_RS06420 (H7786_06475) asnA 1275478..1276470 (-) 993 WP_023611792.1 aspartate--ammonia ligase -
  H7786_RS06425 (H7786_06480) arcC 1276783..1277733 (-) 951 WP_010922501.1 carbamate kinase -
  H7786_RS06430 (H7786_06485) - 1277753..1279084 (-) 1332 WP_030126384.1 dipeptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37555.27 Da        Isoelectric Point: 9.6692

>NTDB_id=477538 H7786_RS06405 WP_002983824.1 1273311..1274348(-) (sepM) [Streptococcus pyogenes strain TSPY270]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTIQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=477538 H7786_RS06405 WP_002983824.1 1273311..1274348(-) (sepM) [Streptococcus pyogenes strain TSPY270]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGCAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGATTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9C0Q7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.986

100

0.69