Detailed information
Bioinformatically predicted
Overview
| Name | radA | Type | Machinery gene |
| Locus tag | H7786_RS01150 | Genome accession | NZ_CP060649 |
| Coordinates | 209113..210474 (+) | Length | 453 a.a. |
| NCBI ID | WP_002986109.1 | Uniprot ID | A0A4Q1R665 |
| Organism | Streptococcus pyogenes strain TSPY270 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 173545..209032 | 209113..210474 | flank | 81 |
Gene organization within MGE regions
Location: 173545..210474
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7786_RS00990 (H7786_00995) | - | 173545..174741 (+) | 1197 | WP_002986345.1 | glycine betaine/L-proline ABC transporter ATP-binding protein | - |
| H7786_RS00995 (H7786_01000) | - | 174757..176484 (+) | 1728 | WP_023610600.1 | ABC transporter permease/substrate binding protein | - |
| H7786_RS01000 (H7786_01005) | polA | 176615..179257 (+) | 2643 | WP_030126424.1 | DNA polymerase I | - |
| H7786_RS01005 (H7786_01010) | - | 179444..179899 (+) | 456 | WP_030126423.1 | CoA-binding protein | - |
| H7786_RS01010 (H7786_01015) | perR | 179951..180418 (+) | 468 | WP_002986328.1 | peroxide-responsive transcriptional repressor PerR | - |
| H7786_RS01015 (H7786_01020) | - | 180637..180873 (+) | 237 | WP_227868539.1 | hypothetical protein | - |
| H7786_RS01020 (H7786_01025) | - | 181095..182429 (+) | 1335 | WP_002987923.1 | phosphoadenosine phosphosulfate reductase | - |
| H7786_RS01025 (H7786_01030) | - | 182422..182952 (+) | 531 | WP_002987925.1 | IbrB-like domain-containing protein | - |
| H7786_RS01030 (H7786_01035) | - | 182999..183148 (-) | 150 | Protein_159 | ISL3 family transposase | - |
| H7786_RS01035 (H7786_01040) | - | 183281..184431 (-) | 1151 | Protein_160 | IS3 family transposase | - |
| H7786_RS01040 (H7786_01045) | - | 184509..185819 (-) | 1311 | WP_002984130.1 | SLC13 family permease | - |
| H7786_RS01045 (H7786_01050) | nadC | 186043..186915 (+) | 873 | WP_228646616.1 | carboxylating nicotinate-nucleotide diphosphorylase | - |
| H7786_RS01050 (H7786_01055) | - | 187215..188526 (-) | 1312 | Protein_163 | IS3 family transposase | - |
| H7786_RS01055 (H7786_01060) | - | 188612..189475 (-) | 864 | WP_002987944.1 | DUF975 family protein | - |
| H7786_RS09130 | - | 189512..189697 (+) | 186 | WP_002986321.1 | hypothetical protein | - |
| H7786_RS01060 (H7786_01065) | tgt | 189694..190836 (+) | 1143 | WP_011528208.1 | tRNA guanosine(34) transglycosylase Tgt | - |
| H7786_RS01065 (H7786_01070) | - | 191053..191364 (+) | 312 | WP_030126467.1 | CHY zinc finger protein | - |
| H7786_RS01070 (H7786_01075) | - | 191368..191907 (+) | 540 | WP_002986314.1 | biotin transporter BioY | - |
| H7786_RS01075 (H7786_01080) | - | 192046..192825 (+) | 780 | WP_030126468.1 | MBL fold metallo-hydrolase | - |
| H7786_RS01080 (H7786_01085) | tadA | 192825..193340 (+) | 516 | WP_030126469.1 | tRNA adenosine(34) deaminase TadA | - |
| H7786_RS01085 (H7786_01090) | - | 193954..195186 (-) | 1233 | WP_030126470.1 | transglutaminase domain-containing protein | - |
| H7786_RS01095 (H7786_01100) | speG | 195586..196290 (+) | 705 | WP_030126471.1 | streptococcal pyrogenic exotoxin SpeG | - |
| H7786_RS01100 (H7786_01105) | - | 196746..198095 (+) | 1350 | WP_014635263.1 | glucose-6-phosphate isomerase | - |
| H7786_RS01105 (H7786_01110) | - | 198444..199952 (-) | 1509 | WP_002986134.1 | helix-turn-helix domain-containing protein | - |
| H7786_RS01110 (H7786_01115) | - | 200640..201311 (+) | 672 | WP_011017305.1 | rhomboid family intramembrane serine protease | - |
| H7786_RS01115 (H7786_01120) | galU | 201410..202309 (-) | 900 | WP_030126472.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| H7786_RS01120 (H7786_01125) | - | 202342..203358 (-) | 1017 | WP_002986123.1 | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase | - |
| H7786_RS01125 (H7786_01130) | - | 203656..204105 (+) | 450 | WP_002986120.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| H7786_RS01130 (H7786_01135) | - | 204098..205804 (+) | 1707 | WP_011284484.1 | ABC transporter ATP-binding protein | - |
| H7786_RS01135 (H7786_01140) | - | 205807..207591 (+) | 1785 | WP_030126473.1 | ABC transporter ATP-binding protein | - |
| H7786_RS01140 (H7786_01145) | - | 207709..208476 (+) | 768 | WP_002986113.1 | epoxyqueuosine reductase QueH | - |
| H7786_RS01145 (H7786_01150) | - | 208586..209032 (+) | 447 | WP_030126474.1 | dUTP diphosphatase | - |
| H7786_RS01150 (H7786_01155) | radA | 209113..210474 (+) | 1362 | WP_002986109.1 | DNA repair protein RadA | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 49386.68 Da Isoelectric Point: 6.0962
>NTDB_id=477509 H7786_RS01150 WP_002986109.1 209113..210474(+) (radA) [Streptococcus pyogenes strain TSPY270]
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
Nucleotide
Download Length: 1362 bp
>NTDB_id=477509 H7786_RS01150 WP_002986109.1 209113..210474(+) (radA) [Streptococcus pyogenes strain TSPY270]
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAATATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGGCCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGAACGGTTCTTTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTTCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATTGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGTTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGCTTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTTGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAATATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGGCCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGAACGGTTCTTTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTTCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATTGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGTTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGCTTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTTGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| radA | Streptococcus mitis NCTC 12261 |
85.872 |
100 |
0.859 |
| radA | Streptococcus pneumoniae D39 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae R6 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae Rx1 |
85.651 |
100 |
0.857 |
| radA | Streptococcus mitis SK321 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae TIGR4 |
85.651 |
100 |
0.857 |
| radA | Bacillus subtilis subsp. subtilis str. 168 |
61.369 |
100 |
0.614 |