Detailed information NTG0477320

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: H7790_RS06355
• Genome accession: NZ_CP060645
• Coordinates: 1266985..1268022 (-)
• Length: 345 a.a.
• NCBI ID: WP_115230462.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY1349
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1261985..1273022

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7790_RS06330 (H7790_06350)	-	1261989..1262516 (-)	528	WP_002983837.1	Dps family protein	-
H7790_RS06335 (H7790_06355)	-	1262744..1263370 (+)	627	WP_002989076.1	prepilin peptidase	-
H7790_RS06340 (H7790_06360)	rlmN	1263452..1264531 (-)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
H7790_RS06345 (H7790_06365)	-	1264535..1265155 (-)	621	WP_002992791.1	YutD family protein	-
H7790_RS06350 (H7790_06370)	-	1265603..1266580 (-)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
H7790_RS06355 (H7790_06375)	sepM	1266985..1268022 (-)	1038	WP_115230462.1	SepM family pheromone-processing serine protease	Regulator
H7790_RS06360 (H7790_06380)	coaD	1268009..1268500 (-)	492	WP_115230461.1	pantetheine-phosphate adenylyltransferase	-
H7790_RS06365 (H7790_06385)	rsmD	1268490..1269029 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
H7790_RS06370 (H7790_06390)	asnA	1269156..1270148 (-)	993	WP_023611792.1	aspartate--ammonia ligase	-
H7790_RS06375 (H7790_06395)	arcC	1270461..1271411 (-)	951	WP_010922501.1	carbamate kinase	-
H7790_RS06380 (H7790_06400)	-	1271431..1272762 (-)	1332	WP_136073820.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37571.33 Da
• Isoelectric Point: 9.6692

>NTDB_id=477320 H7790_RS06355 WP_115230462.1 1266985..1268022(-) (sepM) [Streptococcus pyogenes strain TSPY1349]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVMVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=477320 H7790_RS06355 WP_115230462.1 1266985..1268022(-) (sepM) [Streptococcus pyogenes strain TSPY1349]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCGCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTATGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.275	100	0.693