Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   H7791_RS05655 Genome accession   NZ_CP060644
Coordinates   1156882..1157919 (-) Length   345 a.a.
NCBI ID   WP_010922499.1    Uniprot ID   A0A4U9I5V9
Organism   Streptococcus pyogenes strain TSPY1309     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1151882..1162919
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7791_RS05635 (H7791_05630) - 1152632..1153258 (+) 627 WP_002983834.1 prepilin peptidase -
  H7791_RS05640 (H7791_05635) rlmN 1153340..1154419 (-) 1080 WP_011184761.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  H7791_RS05645 (H7791_05640) - 1154423..1155043 (-) 621 WP_002992791.1 YutD family protein -
  H7791_RS05650 (H7791_05645) - 1155491..1156468 (-) 978 WP_136114625.1 LacI family DNA-binding transcriptional regulator -
  H7791_RS05655 (H7791_05650) sepM 1156882..1157919 (-) 1038 WP_010922499.1 SepM family pheromone-processing serine protease Regulator
  H7791_RS05660 (H7791_05655) coaD 1157906..1158397 (-) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  H7791_RS05665 (H7791_05660) rsmD 1158387..1158926 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  H7791_RS05670 (H7791_05665) asnA 1159049..1160041 (-) 993 WP_010922500.1 aspartate--ammonia ligase -
  H7791_RS05675 (H7791_05670) arcC 1160354..1161304 (-) 951 WP_063631992.1 carbamate kinase -
  H7791_RS05680 (H7791_05675) - 1161324..1162655 (-) 1332 WP_009880963.1 dipeptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37541.24 Da        Isoelectric Point: 9.6692

>NTDB_id=477264 H7791_RS05655 WP_010922499.1 1156882..1157919(-) (sepM) [Streptococcus pyogenes strain TSPY1309]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=477264 H7791_RS05655 WP_010922499.1 1156882..1157919(-) (sepM) [Streptococcus pyogenes strain TSPY1309]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGCTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9I5V9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

69.275

100

0.693