Detailed information NTG0477199

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: H7792_RS02960
• Genome accession: NZ_CP060643
• Coordinates: 584365..585402 (+)
• Length: 345 a.a.
• NCBI ID: WP_111684731.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY416
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 579365..590402

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7792_RS02935 (H7792_02920)	-	579629..580960 (+)	1332	WP_111713718.1	dipeptidase	-
H7792_RS02940 (H7792_02925)	arcC	580980..581930 (+)	951	WP_010922501.1	carbamate kinase	-
H7792_RS02945 (H7792_02930)	asnA	582243..583235 (+)	993	WP_023611792.1	aspartate--ammonia ligase	-
H7792_RS02950 (H7792_02935)	rsmD	583358..583897 (+)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
H7792_RS02955 (H7792_02940)	coaD	583887..584378 (+)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
H7792_RS02960 (H7792_02945)	sepM	584365..585402 (+)	1038	WP_111684731.1	SepM family pheromone-processing serine protease	Regulator
H7792_RS02965 (H7792_02950)	-	585807..586784 (+)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
H7792_RS02970 (H7792_02955)	-	587232..587852 (+)	621	WP_002992791.1	YutD family protein	-
H7792_RS02975 (H7792_02960)	rlmN	587856..588935 (+)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
H7792_RS02980 (H7792_02965)	-	589017..589643 (-)	627	WP_002983834.1	prepilin peptidase	-
H7792_RS02985 (H7792_02970)	-	589871..590398 (+)	528	WP_002983837.1	Dps family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37571.27 Da
• Isoelectric Point: 9.6692

>NTDB_id=477199 H7792_RS02960 WP_111684731.1 584365..585402(+) (sepM) [Streptococcus pyogenes strain TSPY416]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTIQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRS
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=477199 H7792_RS02960 WP_111684731.1 584365..585402(+) (sepM) [Streptococcus pyogenes strain TSPY416]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGCAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGATTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCCAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGTCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAG

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.696	100	0.687