Detailed information NTG0477050

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: H7796_RS05630
• Genome accession: NZ_CP060640
• Coordinates: 1150753..1151790 (-)
• Length: 345 a.a.
• NCBI ID: WP_111693301.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY764
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1145753..1156790

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7796_RS05605 (H7796_05620)	-	1145757..1146284 (-)	528	WP_002983837.1	Dps family protein	-
H7796_RS05610 (H7796_05625)	-	1146512..1147138 (+)	627	WP_136274263.1	prepilin peptidase	-
H7796_RS05615 (H7796_05630)	rlmN	1147220..1148299 (-)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
H7796_RS05620 (H7796_05635)	-	1148303..1148923 (-)	621	WP_002992791.1	YutD family protein	-
H7796_RS05625 (H7796_05640)	-	1149371..1150348 (-)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
H7796_RS05630 (H7796_05645)	sepM	1150753..1151790 (-)	1038	WP_111693301.1	SepM family pheromone-processing serine protease	Regulator
H7796_RS05635 (H7796_05650)	coaD	1151777..1152268 (-)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
H7796_RS05640 (H7796_05655)	rsmD	1152258..1152797 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
H7796_RS05645 (H7796_05660)	asnA	1152920..1153912 (-)	993	WP_136274266.1	aspartate--ammonia ligase	-
H7796_RS05650 (H7796_05665)	arcC	1154225..1155175 (-)	951	WP_009880962.1	carbamate kinase	-
H7796_RS05655 (H7796_05670)	-	1155195..1156526 (-)	1332	WP_136274268.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37527.22 Da
• Isoelectric Point: 9.6692

>NTDB_id=477050 H7796_RS05630 WP_111693301.1 1150753..1151790(-) (sepM) [Streptococcus pyogenes strain TSPY764]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRSVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=477050 H7796_RS05630 WP_111693301.1 1150753..1151790(-) (sepM) [Streptococcus pyogenes strain TSPY764]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGTCTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGAGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.565	100	0.696