Detailed information NTG0476996

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: H7797_RS06760
• Genome accession: NZ_CP060639
• Coordinates: 1345944..1346981 (-)
• Length: 345 a.a.
• NCBI ID: WP_111693301.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY153
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1340944..1351981

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7797_RS06735 (H7797_06705)	-	1340948..1341475 (-)	528	WP_014635585.1	Dps family protein	-
H7797_RS06740 (H7797_06710)	-	1341703..1342329 (+)	627	WP_002989076.1	prepilin peptidase	-
H7797_RS06745 (H7797_06715)	rlmN	1342411..1343490 (-)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
H7797_RS06750 (H7797_06720)	-	1343494..1344114 (-)	621	WP_002992791.1	YutD family protein	-
H7797_RS06755 (H7797_06725)	-	1344562..1345539 (-)	978	WP_109991723.1	LacI family DNA-binding transcriptional regulator	-
H7797_RS06760 (H7797_06730)	sepM	1345944..1346981 (-)	1038	WP_111693301.1	SepM family pheromone-processing serine protease	Regulator
H7797_RS06765 (H7797_06735)	coaD	1346968..1347459 (-)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
H7797_RS06770 (H7797_06740)	rsmD	1347449..1347988 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
H7797_RS06775 (H7797_06745)	asnA	1348111..1349103 (-)	993	WP_023611792.1	aspartate--ammonia ligase	-
H7797_RS06780 (H7797_06750)	arcC	1349417..1350367 (-)	951	WP_009880962.1	carbamate kinase	-
H7797_RS06785 (H7797_06755)	-	1350387..1351718 (-)	1332	WP_032460502.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37527.22 Da
• Isoelectric Point: 9.6692

>NTDB_id=476996 H7797_RS06760 WP_111693301.1 1345944..1346981(-) (sepM) [Streptococcus pyogenes strain TSPY153]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRSVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=476996 H7797_RS06760 WP_111693301.1 1345944..1346981(-) (sepM) [Streptococcus pyogenes strain TSPY153]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGTCTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGAGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.565	100	0.696