Detailed information NTG0047699

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: LLH_RS09190
• Genome accession: NC_017492
• Coordinates: 1825444..1827894 (-)
• Length: 816 a.a.
• NCBI ID: WP_014573025.1
• Uniprot ID: -
• Organism: Lactococcus cremoris subsp. cremoris A76
• Function: degradation of ComX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1828739..1829925	1825444..1827894	flank	845

Gene organization within MGE regions

Location: 1825444..1829925

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLH_RS09190 (llh_9780)	clpC	1825444..1827894 (-)	2451	WP_014573025.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
LLH_RS09195 (llh_9785)	-	1827884..1828339 (-)	456	WP_011834627.1	CtsR family transcriptional regulator	-
LLH_RS13690	-	1828557..1829925 (+)	1369	Protein_1790	IS3-like element ISLla3 family transposase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90280.62 Da
• Isoelectric Point: 6.5301

>NTDB_id=47699 LLH_RS09190 WP_014573025.1 1825444..1827894(-) (clpC) [Lactococcus cremoris subsp. cremoris A76]
MKFENVKYTPTLDRIFEKAAEDAHQYQYGTIESAHLLAAMATTSGSIAYSILAGMNVDSSDLLIDLEDLSSHVKVKRSEL
RFSPRAEEVVTVASFLAVHNNAEAVGTEHLLYALLQVEDGFGIQLLKLQKINIVSLRKEIEKRTGLKVPENKKAVTPMSK
RKMAKGVAENSSTPTLDSVSSDLTEAARSGKLDPMIGREAEVDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSADPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVTLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQETKRLELEKDLVKAQEELAEAVIKLDVKASRIKEKAVEKISDKIYKFSIKEEKRQEV
TDQAVIAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFIFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMQSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAIKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
ISIGASNKKIKIAQIV

Nucleotide

• Length: 2451 bp

>NTDB_id=47699 LLH_RS09190 WP_014573025.1 1825444..1827894(-) (clpC) [Lactococcus cremoris subsp. cremoris A76]
ATGAAATTTGAAAATGTAAAATATACACCAACACTGGACCGAATTTTCGAGAAAGCAGCAGAAGATGCCCACCAATATCA
ATACGGTACGATTGAAAGTGCTCATTTATTGGCAGCAATGGCTACTACTTCAGGCTCAATTGCTTACAGTATTCTTGCTG
GAATGAATGTTGATTCTTCAGACTTACTGATTGATTTGGAAGATTTATCTAGCCATGTCAAAGTGAAACGTTCTGAATTA
CGTTTCTCTCCTCGCGCAGAAGAAGTGGTCACTGTAGCTAGCTTTTTAGCTGTTCATAATAATGCAGAAGCAGTAGGAAC
GGAGCATTTGCTTTATGCATTACTTCAAGTCGAAGATGGTTTTGGTATTCAACTTTTGAAGTTACAAAAAATCAATATTG
TTTCTTTGCGAAAAGAAATTGAAAAAAGAACAGGACTTAAAGTTCCAGAAAACAAAAAAGCTGTAACACCAATGTCCAAA
CGTAAGATGGCAAAAGGGGTAGCAGAGAATTCAAGTACACCAACTTTGGATTCAGTTTCTTCAGATTTAACTGAAGCTGC
TCGTTCAGGAAAGCTTGACCCAATGATTGGTCGGGAAGCAGAAGTTGACCGTTTGATTCATATTCTTAGTCGTAGAACAA
AAAATAACCCTGTTTTAGTTGGCGAACCTGGTGTTGGTAAATCAGCAATAATCGAGGGATTGGCTCAAAGAATTGTCAAC
GGCCAAGTACCTATCGGTTTGATGAATAGCCGGATTATGGCCCTAAATATGGCAACTGTTGTTGCTGGTACAAAATTTAG
AGGTGAATTTGAAGACCGCTTGACAGCAATTGTTGAAGAAGTAAGTGCTGACCCAGATGTCATCATTTTCATTGATGAAT
TGCATACAATTATTGGTGCTGGCGGGGGCATGGACTCGGTCAATGATGCAGCAAATATTTTAAAACCAGCCCTTGCACGT
GGTGATTTTCAAATGGTTGGGGCAACGACTTATCACGAATACCAAAAATACATTGAAAAAGATGAAGCATTAGAACGTCG
TTTGGCAAGAATCAATGTTGATGAGCCAAGTCCAGATGAAGCCATTGCTATCCTACAAGGGTTACGTGAGAAATTTGAAG
ATTATCATCAAGTAAAATTTACTGACCAAGCGATTAAAAGCGCTGTGACACTTAGTGTTCGGTACATGACCAGTCGCAAA
TTGCCTGATAAAGCCATCGACTTGCTTGATGAAGCAGCGGCAGCAGTTAAAATTTCTGTTAAAAACCAAGAAACAAAACG
TCTTGAATTAGAGAAAGACTTAGTTAAAGCTCAAGAAGAACTAGCGGAAGCTGTCATTAAACTTGATGTTAAAGCCTCTC
GCATCAAAGAAAAAGCTGTTGAAAAAATTTCTGACAAGATTTATAAATTCTCAATAAAAGAGGAAAAACGTCAAGAAGTT
ACTGACCAAGCTGTTATTGCTGTTGCCTCAACGCTGACAGGTGTTCCAATTACTCAAATGACTAAATCTGAAAGCGACCG
TTTGATTAATCTTGAAAAAGAATTGCACAAACGGGTCGTTGGTCAAGAAGAAGCAATTTCTGCGGTTTCAAGAGCCATTC
GTCGGGCACGTTCTGGTGTGGCTGATAGTCGCCGTCCAATGGGTTCATTTATATTTCTTGGACCAACTGGTGTTGGGAAA
ACTGAGTTAGCTAAGGCCTTGGCCGATAGTGTTTTTGGTAGCGAAGACAACATGATTCGAGTGGATATGAGTGAATTTAT
GGAAAAACATTCAACTTCACGATTGATTGGAGCACCTCCAGGATATGTTGGTTATGATGAAGGTGGTCAATTGACTGAAC
GTGTTCGTAATAAACCCTATTCTGTGGTTCTTTTAGATGAAGTTGAGAAAGCTCATCCTGACGTTTTCAATATCATGTTG
CAAATTCTAGATGATGGATTTGTGACAGATACAAAGGGTCGCAAAGTTGATTTTAGAAACACAATTATTATCATGACTTC
AAACTTGGGTGCAACGGCTCTTCGTGATGATAAAACAGTTGGTTTTGGTGCAAAAAATATCACGGCTGACTACTCAGCTA
TGCAATCAAGAATTTTGGAAGAACTTAAACGTCATTATCGTCCAGAGTTTCTCAATCGTATTGATGAAAACATTGTTTTC
CATTCATTGGAAAGTCAAGAAATTGAACAAATTGTTAAGATTATGAGCAAATCTTTGATTAAACGTTTGGCGGAACAAGA
TATTCATGTGAAACTTACGCCATCAGCAATAAAACTAATCGCTGAAGTAGGATTTGACCCAGAATATGGGGCACGTCCAT
TGCGTAAAGCACTCCAAAAAGAAGTTGAAGATCTTTTAAGTGAGCAATTGCTCTCGGGTGAGATTAAAGCAGGAAATCAT
ATTTCCATTGGTGCTTCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (218-334)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-144)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (23-69)

• AAA lid domain (AAA_lid_9) (357-449)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	95.711	100	0.957
clpC	Streptococcus thermophilus LMD-9	50.903	100	0.518
clpC	Streptococcus thermophilus LMG 18311	50.782	100	0.517
clpC	Streptococcus pneumoniae Rx1	49.396	100	0.501
clpC	Streptococcus pneumoniae D39	49.396	100	0.501
clpC	Streptococcus pneumoniae TIGR4	49.275	100	0.5
clpC	Streptococcus mutans UA159	48.798	100	0.498
clpC	Bacillus subtilis subsp. subtilis str. 168	50.374	98.284	0.495
clpE	Streptococcus mutans UA159	46.923	79.657	0.374
clpC	Lactococcus lactis subsp. cremoris KW2	46.626	79.902	0.373
clpE	Streptococcus pneumoniae TIGR4	47.049	76.838	0.362
clpE	Streptococcus pneumoniae Rx1	47.049	76.838	0.362
clpE	Streptococcus pneumoniae D39	47.049	76.838	0.362
clpE	Streptococcus pneumoniae R6	47.049	76.838	0.362