Detailed information NTG0476953

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: H7798_RS08685
• Genome accession: NZ_CP060638
• Coordinates: 1765407..1767851 (-)
• Length: 814 a.a.
• NCBI ID: WP_111718019.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY141
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1760407..1772851

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7798_RS08660 (H7798_08695)	-	1760560..1762059 (+)	1500	WP_053308655.1	C69 family dipeptidase	-
H7798_RS08665	-	1762443..1762718 (+)	276	Protein_1679	NUDIX domain-containing protein	-
H7798_RS08670 (H7798_08700)	-	1762765..1763070 (-)	306	WP_111676844.1	helix-turn-helix domain-containing protein	-
H7798_RS08675 (H7798_08705)	groL	1763272..1764903 (-)	1632	WP_002982320.1	chaperonin GroEL	-
H7798_RS08680 (H7798_08710)	groES	1764939..1765229 (-)	291	WP_002991292.1	co-chaperone GroES	-
H7798_RS08685 (H7798_08715)	clpC	1765407..1767851 (-)	2445	WP_111718019.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
H7798_RS08690 (H7798_08720)	-	1767851..1768312 (-)	462	WP_038431663.1	CtsR family transcriptional regulator	-
H7798_RS08695 (H7798_08725)	-	1768508..1768711 (-)	204	WP_002991299.1	cold-shock protein	-
H7798_RS08705 (H7798_08735)	ahpC	1769697..1770257 (+)	561	WP_002982304.1	alkyl hydroperoxide reductase subunit C	-
H7798_RS08710 (H7798_08740)	ahpF	1770278..1771810 (+)	1533	WP_023610722.1	alkyl hydroperoxide reductase subunit F	-

Sequence

Protein

• Length: 814 a.a.
• Molecular weight: 90641.36 Da
• Isoelectric Point: 7.0703

>NTDB_id=476953 H7798_RS08685 WP_111718019.1 1765407..1767851(-) (clpC) [Streptococcus pyogenes strain TSPY141]
MIMYSTKMQDIFRQAQFQAARFDSHCLETWHVLLAMVAVDNSLANMILSEYDAQVAIEEYEAAAILAMGKTPKEQLSRVD
FRPQSKTLTNLLAFAQAISQITRDQEVGSEHVLFAILLNPDIMASRLLEIAGYQIKDNGNGQPRLADLRKAIERHAGYSK
EMIKAIHELRKPKKTKTQGTFSDMMKPPSTAGELSDFTRDLTEMARQGLLESVIGRDQEVSRMIQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIANGAIPYELKEMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIEADGQIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNTEDAYQILMGLKLSYETYHNVSISN
EAVKTAVKMAHRYLTSKNLPDSAIDLLDEASAAVQNMVKKSAPETLTPIDQALINGDMKKVSRLLAKKAKGQMRNPTPVT
EDDILATLSKLSGIPLEKLTQADSKKYLNLEKELHKRVIGQDAAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDEAALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTQKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGILTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGVKGIHQDHQAMEKRILEELRKTYRPEFINRIDEKVVFH
SLTQDNMRDVVKIMVQPLITTLAEKGITLKIQPLALKHLSEVGYDEHMGARPLRRTLQTEIEDKLSELILSRELTSGHTL
KIGLSHGKLTFHIA

Nucleotide

• Length: 2445 bp

>NTDB_id=476953 H7798_RS08685 WP_111718019.1 1765407..1767851(-) (clpC) [Streptococcus pyogenes strain TSPY141]
ATGATTATGTATTCAACGAAGATGCAAGACATTTTTAGACAGGCGCAGTTCCAAGCTGCTCGCTTTGACAGCCATTGCCT
GGAAACTTGGCATGTTTTGTTAGCTATGGTAGCTGTAGATAATTCTTTAGCAAATATGATTTTAAGTGAATATGATGCCC
AAGTCGCCATAGAAGAATATGAAGCTGCAGCTATTTTAGCCATGGGCAAAACCCCTAAGGAACAGTTGTCTCGTGTAGAC
TTCAGACCTCAATCTAAAACCTTGACTAACTTGTTAGCTTTTGCGCAGGCTATTAGCCAAATCACTAGGGATCAAGAAGT
CGGCTCTGAGCATGTCTTATTTGCTATTTTATTGAATCCAGATATCATGGCGAGTCGTTTGTTAGAAATAGCAGGCTATC
AGATAAAAGATAACGGCAATGGGCAGCCGCGATTAGCTGACTTACGAAAAGCAATAGAACGTCATGCAGGTTACAGTAAG
GAAATGATCAAGGCTATTCACGAACTACGTAAGCCTAAAAAAACGAAAACACAAGGGACCTTTTCAGATATGATGAAGCC
ACCAAGTACAGCTGGTGAGTTGAGTGATTTCACAAGAGATTTGACTGAAATGGCAAGACAAGGTTTGTTAGAATCGGTGA
TTGGACGTGACCAAGAAGTATCTCGTATGATTCAGGTACTAAGTCGTAAAACGAAAAACAATCCTGTCTTGGTAGGTGAT
GCAGGTGTTGGTAAAACTGCGCTTGCTTATGGCCTTGCTCAACGGATTGCAAATGGCGCTATTCCTTATGAACTTAAGGA
GATGCGTGTCCTAGAATTAGACATGATGAGTGTGGTAGCAGGAACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATC
AAATCATTGATGATATTGAAGCTGATGGTCAGATTATTCTTTTTGTTGATGAACTACATACTATTATGGGTTCTGGCAGT
GGTATTGACAGTACACTTGATGCGGCTAACATTTTAAAACCAGCATTATCGCGCGGCACTCTTCATATGGTTGGAGCAAC
AACTCAAGAAGAATACCAAAAACATATTGAAAAAGATGCAGCTCTTTCGCGTCGTTTTGCTAAAATATTAATTGAAGAAC
CTAATACAGAAGATGCTTATCAGATTTTGATGGGCCTAAAATTATCTTATGAGACCTACCATAATGTCTCGATATCAAAT
GAGGCAGTTAAAACAGCTGTAAAAATGGCACACCGTTATTTAACCAGTAAAAATCTCCCTGATTCAGCTATCGATTTATT
AGATGAAGCTAGTGCTGCTGTGCAAAACATGGTGAAAAAATCAGCACCTGAGACTTTAACACCAATAGACCAAGCTCTTA
TCAATGGTGATATGAAAAAAGTATCTCGCCTCTTAGCTAAAAAAGCAAAAGGTCAGATGAGAAACCCAACACCGGTGACA
GAAGATGATATTTTGGCAACCTTGAGTAAGTTATCGGGAATTCCACTTGAAAAACTGACGCAAGCTGATAGTAAAAAATA
CCTCAATTTAGAAAAAGAACTGCATAAGCGTGTGATTGGTCAGGATGCTGCTGTTACGGCTATTTCAAGAGCCATTCGTC
GTAATCAGTCAGGTATTCGAACAGGAAAACGTCCTATTGGATCATTTATGTTTCTTGGCCCAACAGGAGTAGGTAAGACA
GAACTAGCAAAGGCCCTTGCAGAAGTTCTCTTTGATGATGAAGCAGCGCTTATTCGTTTTGATATGTCTGAGTACATGGA
AAAATTCGCAGCGTCTAGGCTTAATGGAGCACCTCCTGGTTATGTCGGCTATGATGAAGGAGGTGAACTGACACAGAAAG
TTAGAAATAAACCTTATTCAGTCTTGCTTTTTGATGAAGTGGAAAAAGCACATCCTGATATTTTTAACGTTCTCCTTCAA
GTATTAGATGATGGTATATTGACTGATAGTCGTGGGCGTAAGGTCGATTTTTCAAATACTATTATTATCATGACCAGCAA
TCTTGGCGCAACAGCCCTGCGCGATGATAAAACGGTCGGTTTTGGGGTCAAAGGCATTCACCAAGACCATCAAGCTATGG
AGAAACGTATTTTAGAAGAATTAAGAAAAACTTACCGCCCAGAATTTATCAATCGTATTGATGAAAAAGTGGTCTTTCAT
AGTCTGACCCAAGATAACATGCGCGATGTGGTTAAAATCATGGTACAGCCCCTGATTACTACATTGGCAGAAAAAGGTAT
TACCCTTAAAATTCAGCCTTTGGCCTTGAAACATTTGTCCGAGGTCGGCTATGATGAGCATATGGGGGCAAGACCATTAC
GTCGAACGCTGCAAACTGAGATAGAAGATAAGCTATCAGAGCTTATTCTTTCTCGAGAATTGACAAGTGGGCATACGCTA
AAAATTGGATTATCACATGGCAAATTAACGTTTCACATAGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-801)

• AAA lid domain (AAA_lid_9) (376-457)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-130)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	74.908	99.877	0.748
clpC	Streptococcus thermophilus LMG 18311	71.201	100	0.714
clpC	Streptococcus thermophilus LMD-9	71.078	100	0.713
clpC	Streptococcus pneumoniae TIGR4	65.725	100	0.657
clpC	Streptococcus pneumoniae Rx1	65.725	100	0.657
clpC	Streptococcus pneumoniae D39	65.725	100	0.657
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.733	100	0.491
clpC	Bacillus subtilis subsp. subtilis str. 168	42.308	100	0.432