Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   H8S71_RS06140 Genome accession   NZ_CP060417
Coordinates   1193718..1194374 (+) Length   218 a.a.
NCBI ID   WP_003245194.1    Uniprot ID   A0AAE2VF25
Organism   Bacillus subtilis subsp. subtilis strain ONU 559     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1188718..1199374
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H8S71_RS06110 (H8S71_06105) oppF 1189180..1190097 (+) 918 WP_003239287.1 oligopeptide ABC transporter ATP-binding protein OppF -
  H8S71_RS06115 (H8S71_06110) yjbB 1190204..1191421 (+) 1218 WP_072175656.1 MFS transporter -
  H8S71_RS06120 (H8S71_06115) yjbC 1191585..1192163 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  H8S71_RS06125 (H8S71_06120) spx 1192344..1192739 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  H8S71_RS06130 (H8S71_06125) yjbE 1192785..1193441 (-) 657 WP_003232944.1 TerC family protein -
  H8S71_RS06135 (H8S71_06130) - 1193611..1193751 (+) 141 WP_119122854.1 hypothetical protein -
  H8S71_RS06140 (H8S71_06135) mecA 1193718..1194374 (+) 657 WP_003245194.1 adaptor protein MecA Regulator
  H8S71_RS06145 (H8S71_06140) - 1194369..1194491 (-) 123 WP_124059721.1 hypothetical protein -
  H8S71_RS06150 (H8S71_06145) coiA 1194535..1195686 (+) 1152 WP_187002183.1 competence protein CoiA Machinery gene
  H8S71_RS06155 (H8S71_06150) pepF 1195916..1197745 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  H8S71_RS06160 (H8S71_06155) - 1197783..1197950 (-) 168 WP_003244944.1 hypothetical protein -
  H8S71_RS06165 (H8S71_06160) spxH 1198265..1199164 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25763.69 Da        Isoelectric Point: 4.1174

>NTDB_id=475876 H8S71_RS06140 WP_003245194.1 1193718..1194374(+) (mecA) [Bacillus subtilis subsp. subtilis strain ONU 559]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=475876 H8S71_RS06140 WP_003245194.1 1193718..1194374(+) (mecA) [Bacillus subtilis subsp. subtilis strain ONU 559]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

100

100

1