Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGE   Type   Machinery gene
Locus tag   CVCAS_RS10710 Genome accession   NC_017486
Coordinates   2144136..2144432 (-) Length   98 a.a.
NCBI ID   WP_010906316.1    Uniprot ID   A0A3N6L9Y1
Organism   Lactococcus lactis subsp. lactis CV56     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2141123..2181769 2144136..2144432 within 0


Gene organization within MGE regions


Location: 2141123..2181769
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVCAS_RS10685 (CVCAS_2098) - 2141123..2141860 (-) 738 WP_003129989.1 metal ABC transporter ATP-binding protein -
  CVCAS_RS10690 (CVCAS_2099) - 2142037..2142879 (-) 843 WP_003129990.1 metal ABC transporter substrate-binding protein -
  CVCAS_RS10695 (CVCAS_2100) - 2142876..2143313 (-) 438 WP_003129992.1 zinc-dependent MarR family transcriptional regulator -
  CVCAS_RS10700 (CVCAS_2101) comGG 2143395..2143688 (-) 294 WP_043991170.1 competence type IV pilus minor pilin ComGG Machinery gene
  CVCAS_RS10705 (CVCAS_2102) comGF 2143727..2144173 (-) 447 WP_029344525.1 competence type IV pilus minor pilin ComGF Machinery gene
  CVCAS_RS10710 (CVCAS_2103) comGE 2144136..2144432 (-) 297 WP_010906316.1 competence type IV pilus minor pilin ComGE Machinery gene
  CVCAS_RS10715 (CVCAS_2104) comGD 2144404..2144835 (-) 432 WP_014570794.1 competence type IV pilus minor pilin ComGD Machinery gene
  CVCAS_RS10720 (CVCAS_2105) comGC 2144795..2145064 (-) 270 WP_003129998.1 competence type IV pilus major pilin ComGC Machinery gene
  CVCAS_RS10725 (CVCAS_2106) - 2145211..2145735 (-) 525 WP_014570795.1 GNAT family N-acetyltransferase -
  CVCAS_RS10730 (CVCAS_2107) - 2145814..2146593 (-) 780 WP_014570796.1 peptidoglycan amidohydrolase family protein -
  CVCAS_RS10735 (CVCAS_2108) - 2146593..2146892 (-) 300 WP_014570797.1 phage holin -
  CVCAS_RS10740 (CVCAS_2109) - 2146905..2147255 (-) 351 WP_014570798.1 hypothetical protein -
  CVCAS_RS10745 (CVCAS_2110) - 2147268..2147504 (-) 237 WP_014570799.1 hypothetical protein -
  CVCAS_RS12920 (CVCAS_2111) - 2147516..2151601 (-) 4086 WP_193363677.1 hypothetical protein -
  CVCAS_RS10760 (CVCAS_2112) - 2151580..2153109 (-) 1530 WP_014570562.1 distal tail protein Dit -
  CVCAS_RS10765 (CVCAS_2113) - 2153119..2155332 (-) 2214 WP_014570561.1 phage tail tape measure protein -
  CVCAS_RS10770 (CVCAS_2114) - 2155322..2156029 (-) 708 WP_014570560.1 Gp15 family bacteriophage protein -
  CVCAS_RS10775 (CVCAS_2115) - 2156045..2156452 (-) 408 WP_003131323.1 hypothetical protein -
  CVCAS_RS10780 (CVCAS_2116) - 2156509..2156985 (-) 477 WP_014570559.1 phage tail tube protein -
  CVCAS_RS10785 (CVCAS_2117) - 2156996..2157430 (-) 435 WP_014570558.1 minor capsid protein -
  CVCAS_RS10790 (CVCAS_2118) - 2157430..2157759 (-) 330 WP_003131320.1 hypothetical protein -
  CVCAS_RS10795 (CVCAS_2119) - 2157756..2158100 (-) 345 WP_014570557.1 putative minor capsid protein -
  CVCAS_RS10800 (CVCAS_2120) - 2158090..2158491 (-) 402 WP_014570556.1 hypothetical protein -
  CVCAS_RS10805 (CVCAS_2121) - 2158565..2158801 (-) 237 WP_014570555.1 Ig-like domain-containing protein -
  CVCAS_RS10810 (CVCAS_2122) - 2158830..2159747 (-) 918 WP_003131315.1 hypothetical protein -
  CVCAS_RS10815 (CVCAS_2123) - 2159762..2160826 (-) 1065 WP_014570554.1 XkdF-like putative serine protease domain-containing protein -
  CVCAS_RS10820 (CVCAS_2124) - 2160842..2161672 (-) 831 WP_014570553.1 phage minor head protein -
  CVCAS_RS10825 (CVCAS_2125) - 2161665..2163194 (-) 1530 WP_014570552.1 phage portal protein -
  CVCAS_RS10830 (CVCAS_2126) terL 2163207..2164658 (-) 1452 WP_014570551.1 phage terminase large subunit -
  CVCAS_RS10835 (CVCAS_2127) - 2164639..2165136 (-) 498 WP_014570801.1 hypothetical protein -
  CVCAS_RS10840 (CVCAS_2128) - 2165165..2166322 (-) 1158 Protein_2112 DNA modification methylase -
  CVCAS_RS10845 (CVCAS_2129) - 2166799..2167221 (-) 423 WP_014570802.1 RinA family protein -
  CVCAS_RS13330 (CVCAS_2130) - 2167299..2167460 (-) 162 WP_003131301.1 hypothetical protein -
  CVCAS_RS10850 - 2167589..2167783 (-) 195 WP_023349206.1 DUF1660 domain-containing protein -
  CVCAS_RS10855 (CVCAS_2131) - 2167780..2167998 (-) 219 WP_014570803.1 hypothetical protein -
  CVCAS_RS10860 (CVCAS_2132) - 2168059..2168382 (-) 324 WP_014570804.1 DUF1140 family protein -
  CVCAS_RS10865 (CVCAS_2133) - 2168385..2168756 (-) 372 WP_014570805.1 hypothetical protein -
  CVCAS_RS13335 (CVCAS_2134) - 2168749..2168901 (-) 153 WP_014570806.1 hypothetical protein -
  CVCAS_RS10875 (CVCAS_2135) - 2168933..2169184 (-) 252 WP_014570807.1 hypothetical protein -
  CVCAS_RS10880 (CVCAS_2136) - 2169181..2169369 (-) 189 WP_014570808.1 hypothetical protein -
  CVCAS_RS13540 (CVCAS_2137) - 2169387..2169749 (-) 363 WP_014570809.1 hypothetical protein -
  CVCAS_RS10890 (CVCAS_2138) - 2169753..2170172 (-) 420 WP_003129863.1 dUTP diphosphatase -
  CVCAS_RS10895 (CVCAS_2139) - 2170169..2170843 (-) 675 WP_014570539.1 DUF1642 domain-containing protein -
  CVCAS_RS10900 (CVCAS_2141) - 2170985..2171374 (-) 390 WP_014570537.1 hypothetical protein -
  CVCAS_RS10905 (CVCAS_2142) - 2171386..2171661 (-) 276 WP_014570536.1 hypothetical protein -
  CVCAS_RS10915 (CVCAS_2144) - 2171984..2172394 (-) 411 WP_014570810.1 hypothetical protein -
  CVCAS_RS10920 (CVCAS_2145) - 2172407..2172649 (-) 243 WP_014570811.1 L-rhamnose isomerase -
  CVCAS_RS10925 (CVCAS_2146) - 2172642..2173556 (-) 915 WP_014570812.1 phage replisome organizer N-terminal domain-containing protein -
  CVCAS_RS10930 (CVCAS_2147) - 2173820..2174746 (-) 927 WP_014570813.1 RecT family recombinase -
  CVCAS_RS10935 (CVCAS_2148) - 2174743..2175576 (-) 834 WP_014570814.1 hypothetical protein -
  CVCAS_RS10940 (CVCAS_2149) - 2175679..2175927 (-) 249 WP_014570815.1 hypothetical protein -
  CVCAS_RS13610 (CVCAS_2150) - 2175941..2176063 (-) 123 WP_014570816.1 hypothetical protein -
  CVCAS_RS10945 - 2176060..2176242 (-) 183 WP_043991177.1 hypothetical protein -
  CVCAS_RS10950 (CVCAS_2152) - 2176258..2176947 (-) 690 WP_014570818.1 phage regulatory protein -
  CVCAS_RS10955 (CVCAS_2153) - 2177006..2177239 (-) 234 WP_014570819.1 helix-turn-helix transcriptional regulator -
  CVCAS_RS10960 (CVCAS_2154) - 2177416..2177826 (+) 411 WP_014570820.1 helix-turn-helix domain-containing protein -
  CVCAS_RS10965 (CVCAS_2155) - 2177837..2178421 (+) 585 WP_014570821.1 hypothetical protein -
  CVCAS_RS10970 (CVCAS_2156) - 2178477..2179016 (+) 540 WP_014570822.1 PH domain-containing protein -
  CVCAS_RS10975 (CVCAS_2157) - 2179142..2180599 (+) 1458 WP_014570823.1 recombinase family protein -
  CVCAS_RS13080 - 2180596..2180736 (-) 141 WP_228777719.1 hypothetical protein -

Sequence


Protein


Download         Length: 98 a.a.        Molecular weight: 11076.95 Da        Isoelectric Point: 6.4684

>NTDB_id=47587 CVCAS_RS10710 WP_010906316.1 2144136..2144432(-) (comGE) [Lactococcus lactis subsp. lactis CV56]
MENLKRKSVKAYLLLESLISIALLAFLVSFIVSSLVQVRQKDTEENQKIEALNVAQMAIESHLTELSINGSDIKIKENQN
LLIISNHGKEIMRLELQS

Nucleotide


Download         Length: 297 bp        

>NTDB_id=47587 CVCAS_RS10710 WP_010906316.1 2144136..2144432(-) (comGE) [Lactococcus lactis subsp. lactis CV56]
GTGGAAAATTTAAAAAGAAAATCAGTTAAGGCATATTTGCTTTTGGAAAGTTTAATTAGTATAGCTCTACTCGCTTTTCT
AGTCAGCTTTATCGTAAGTTCTCTTGTGCAAGTAAGACAAAAAGATACGGAAGAAAATCAAAAGATTGAAGCTTTAAACG
TGGCACAAATGGCGATTGAAAGTCACTTAACAGAATTATCAATCAACGGTTCTGATATAAAGATAAAAGAAAACCAAAAT
TTACTGATTATTAGTAATCATGGAAAGGAAATTATGCGACTTGAACTTCAAAGTTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A3N6L9Y1

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

68.041

98.98

0.673


Multiple sequence alignment