Detailed information
Bioinformatically predicted
Overview
| Name | pilK | Type | Machinery gene |
| Locus tag | H7A79_RS06640 | Genome accession | NZ_CP060414 |
| Coordinates | 1257390..1257908 (-) | Length | 172 a.a. |
| NCBI ID | WP_187001451.1 | Uniprot ID | A0A7H1ME05 |
| Organism | Neisseria musculi strain NW831 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1233526..1273961 | 1257390..1257908 | within | 0 |
Gene organization within MGE regions
Location: 1233526..1273961
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7A79_RS06510 (H7A79_1204) | - | 1233532..1235301 (-) | 1770 | WP_187001645.1 | ABC transporter ATP-binding protein/permease | - |
| H7A79_RS06515 (H7A79_1205) | - | 1235616..1237859 (+) | 2244 | WP_187001439.1 | TonB-dependent receptor | - |
| H7A79_RS06520 | - | 1238174..1238374 (-) | 201 | WP_187001440.1 | hypothetical protein | - |
| H7A79_RS06525 (H7A79_1206) | - | 1238454..1238741 (-) | 288 | WP_135037421.1 | hypothetical protein | - |
| H7A79_RS06530 (H7A79_1207) | rclC | 1239163..1239774 (+) | 612 | WP_281385022.1 | reactive chlorine resistance membrane protein RclC | - |
| H7A79_RS06535 (H7A79_1208) | - | 1239860..1240195 (+) | 336 | WP_135037416.1 | carboxymuconolactone decarboxylase family protein | - |
| H7A79_RS06540 (H7A79_1209) | - | 1240781..1241404 (+) | 624 | WP_187001441.1 | LysE family transporter | - |
| H7A79_RS06545 (H7A79_1210) | - | 1241619..1242104 (+) | 486 | WP_187001442.1 | NemA protein | - |
| H7A79_RS06550 (H7A79_1211) | - | 1242633..1244231 (-) | 1599 | WP_187001443.1 | peptide chain release factor 3 | - |
| H7A79_RS06555 (H7A79_1212) | - | 1244557..1245435 (-) | 879 | WP_187001444.1 | LysR family transcriptional regulator | - |
| H7A79_RS06560 (H7A79_1213) | - | 1245593..1246273 (+) | 681 | WP_187001445.1 | hydrolase | - |
| H7A79_RS06565 | - | 1246314..1246523 (-) | 210 | WP_187001446.1 | hypothetical protein | - |
| H7A79_RS06570 (H7A79_1214) | ycaC | 1246537..1247169 (+) | 633 | Protein_1288 | isochorismate family cysteine hydrolase YcaC | - |
| H7A79_RS06575 (H7A79_1216) | - | 1247387..1247899 (+) | 513 | WP_214646420.1 | alpha/beta hydrolase | - |
| H7A79_RS06580 (H7A79_1217) | - | 1247868..1248329 (+) | 462 | WP_353663635.1 | alpha/beta hydrolase | - |
| H7A79_RS06585 (H7A79_1218) | - | 1248486..1249022 (+) | 537 | WP_135036977.1 | NADPH-dependent FMN reductase | - |
| H7A79_RS06590 (H7A79_1219) | - | 1249107..1249364 (+) | 258 | WP_209304857.1 | DUF2789 family protein | - |
| H7A79_RS06595 (H7A79_1220) | - | 1249408..1250022 (+) | 615 | WP_187001447.1 | glutathione S-transferase N-terminal domain-containing protein | - |
| H7A79_RS06600 | - | 1250309..1250443 (+) | 135 | WP_281385024.1 | hypothetical protein | - |
| H7A79_RS06605 (H7A79_1221) | - | 1250681..1251682 (-) | 1002 | WP_187001448.1 | asparaginase | - |
| H7A79_RS06610 (H7A79_1222) | iscX | 1252039..1252233 (-) | 195 | WP_135036983.1 | Fe-S cluster assembly protein IscX | - |
| H7A79_RS06615 (H7A79_1223) | gshA | 1252744..1254087 (-) | 1344 | WP_135036986.1 | glutamate--cysteine ligase | - |
| H7A79_RS06620 (H7A79_1224) | leuC | 1254328..1255734 (+) | 1407 | WP_187001449.1 | 3-isopropylmalate dehydratase large subunit | - |
| H7A79_RS06625 (H7A79_1225) | - | 1255865..1255999 (+) | 135 | WP_135037165.1 | entericidin A/B family lipoprotein | - |
| H7A79_RS06630 (H7A79_1226) | leuD | 1256075..1256716 (+) | 642 | WP_187001450.1 | 3-isopropylmalate dehydratase small subunit | - |
| H7A79_RS06635 (H7A79_1227) | - | 1256921..1257382 (-) | 462 | WP_135037160.1 | PilX family type IV pilin | - |
| H7A79_RS06640 (H7A79_1228) | pilK | 1257390..1257908 (-) | 519 | WP_187001451.1 | pilus assembly protein | Machinery gene |
| H7A79_RS06645 (H7A79_1229) | - | 1257884..1258786 (-) | 903 | WP_187001452.1 | prepilin-type N-terminal cleavage/methylation domain-containing protein | - |
| H7A79_RS06650 (H7A79_1230) | pilV | 1258806..1259513 (-) | 708 | WP_194198396.1 | type IV pilus modification protein PilV | - |
| H7A79_RS06655 (H7A79_1231) | pilH | 1259599..1260267 (-) | 669 | WP_187001454.1 | GspH/FimT family pseudopilin | Machinery gene |
| H7A79_RS06660 (H7A79_1232) | dnaB | 1260551..1261960 (-) | 1410 | WP_135037149.1 | replicative DNA helicase | - |
| H7A79_RS06665 (H7A79_1233) | - | 1262196..1262729 (+) | 534 | WP_187001455.1 | inorganic diphosphatase | - |
| H7A79_RS06670 (H7A79_1234) | rpe | 1263010..1263693 (-) | 684 | WP_135037143.1 | ribulose-phosphate 3-epimerase | - |
| H7A79_RS06675 (H7A79_1235) | - | 1263908..1264339 (+) | 432 | WP_187001456.1 | hypothetical protein | - |
| H7A79_RS06680 (H7A79_1236) | - | 1264619..1265269 (+) | 651 | WP_186999880.1 | IS1595 family transposase | - |
| H7A79_RS06685 (H7A79_1237) | - | 1265890..1266210 (+) | 321 | WP_187000874.1 | hypothetical protein | - |
| H7A79_RS06690 | - | 1266267..1266530 (+) | 264 | WP_135037661.1 | hypothetical protein | - |
| H7A79_RS06695 (H7A79_1238) | - | 1266626..1267345 (-) | 720 | WP_246408020.1 | hypothetical protein | - |
| H7A79_RS06700 | - | 1267496..1268032 (-) | 537 | WP_246408022.1 | DNA cytosine methyltransferase | - |
| H7A79_RS06705 | - | 1267989..1268336 (-) | 348 | WP_246408024.1 | DNA cytosine methyltransferase | - |
| H7A79_RS06710 | - | 1268409..1268519 (-) | 111 | WP_187000875.1 | Com family DNA-binding transcriptional regulator | - |
| H7A79_RS06715 (H7A79_1241) | istA | 1268582..1270176 (+) | 1595 | Protein_1317 | IS21 family transposase | - |
| H7A79_RS06720 (H7A79_1242) | - | 1270166..1270312 (+) | 147 | WP_246407916.1 | hypothetical protein | - |
| H7A79_RS06725 (H7A79_1243) | istB | 1270294..1270890 (+) | 597 | WP_246407914.1 | IS21-like element helper ATPase IstB | - |
| H7A79_RS06730 (H7A79_1244) | - | 1271058..1271390 (-) | 333 | WP_187001457.1 | hypothetical protein | - |
| H7A79_RS06735 (H7A79_1245) | - | 1271721..1272032 (-) | 312 | WP_187001458.1 | DNA-binding transcriptional regulator | - |
| H7A79_RS06740 | - | 1272029..1272395 (-) | 367 | Protein_1322 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| H7A79_RS06745 (H7A79_1246) | - | 1272483..1272740 (-) | 258 | WP_187001459.1 | hypothetical protein | - |
| H7A79_RS06750 (H7A79_1247) | - | 1273042..1273704 (-) | 663 | WP_186999913.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 172 a.a. Molecular weight: 18938.36 Da Isoelectric Point: 5.9142
>NTDB_id=475826 H7A79_RS06640 WP_187001451.1 1257390..1257908(-) (pilK) [Neisseria musculi strain NW831]
MRQPQPFVTFKPKSAQQGFSLFIVLMVMIVVAFLVVSVTQSYNTEQRISTNDADHKFATALAEAALRTGEKRIADDDLDA
SQFTEDCENALCNVGTNPAWERATCGKSKTESCIDNSSGIFAAREAAQPSRYIIEYISQQPDGSEIYRVTAKAWGKNRNT
VVILQSYVAAGK
MRQPQPFVTFKPKSAQQGFSLFIVLMVMIVVAFLVVSVTQSYNTEQRISTNDADHKFATALAEAALRTGEKRIADDDLDA
SQFTEDCENALCNVGTNPAWERATCGKSKTESCIDNSSGIFAAREAAQPSRYIIEYISQQPDGSEIYRVTAKAWGKNRNT
VVILQSYVAAGK
Nucleotide
Download Length: 519 bp
>NTDB_id=475826 H7A79_RS06640 WP_187001451.1 1257390..1257908(-) (pilK) [Neisseria musculi strain NW831]
ATGCGCCAACCGCAGCCTTTCGTAACTTTTAAACCCAAATCGGCACAACAGGGCTTTTCACTGTTTATTGTATTGATGGT
AATGATTGTAGTGGCTTTTTTGGTAGTAAGCGTAACCCAGTCTTATAACACCGAGCAGCGTATCAGCACCAACGATGCAG
ATCACAAATTTGCTACAGCATTGGCTGAAGCCGCATTGCGGACAGGTGAGAAAAGAATTGCTGACGATGATCTTGATGCA
AGCCAGTTCACAGAAGATTGCGAAAACGCTCTGTGTAATGTAGGCACGAATCCTGCTTGGGAGCGCGCTACCTGTGGAAA
ATCCAAAACCGAATCATGTATAGATAACAGCAGCGGAATATTCGCAGCCAGAGAAGCTGCGCAACCTTCCCGTTATATTA
TTGAATATATCAGCCAGCAGCCTGACGGTTCGGAAATCTACCGCGTAACGGCTAAAGCATGGGGTAAAAACAGAAACACT
GTTGTGATTTTACAGTCTTATGTGGCAGCGGGAAAATAG
ATGCGCCAACCGCAGCCTTTCGTAACTTTTAAACCCAAATCGGCACAACAGGGCTTTTCACTGTTTATTGTATTGATGGT
AATGATTGTAGTGGCTTTTTTGGTAGTAAGCGTAACCCAGTCTTATAACACCGAGCAGCGTATCAGCACCAACGATGCAG
ATCACAAATTTGCTACAGCATTGGCTGAAGCCGCATTGCGGACAGGTGAGAAAAGAATTGCTGACGATGATCTTGATGCA
AGCCAGTTCACAGAAGATTGCGAAAACGCTCTGTGTAATGTAGGCACGAATCCTGCTTGGGAGCGCGCTACCTGTGGAAA
ATCCAAAACCGAATCATGTATAGATAACAGCAGCGGAATATTCGCAGCCAGAGAAGCTGCGCAACCTTCCCGTTATATTA
TTGAATATATCAGCCAGCAGCCTGACGGTTCGGAAATCTACCGCGTAACGGCTAAAGCATGGGGTAAAAACAGAAACACT
GTTGTGATTTTACAGTCTTATGTGGCAGCGGGAAAATAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilK | Neisseria gonorrhoeae MS11 |
46.231 |
100 |
0.535 |