Detailed information NTG0475229

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H7969_RS10170
• Genome accession: NZ_CP060280
• Coordinates: 2026202..2027389 (+)
• Length: 395 a.a.
• NCBI ID: WP_002224381.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain LNP24198
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2021202..2032389

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7969_RS10155 (H7969_10155)	-	2022125..2022724 (+)	600	WP_002216221.1	DUF4390 domain-containing protein	-
H7969_RS10160 (H7969_10160)	-	2022724..2024841 (+)	2118	WP_002224380.1	PAS domain-containing sensor histidine kinase	-
H7969_RS10165 (H7969_10165)	-	2024834..2026111 (+)	1278	WP_002220140.1	sigma-54 dependent transcriptional regulator	-
H7969_RS10170 (H7969_10170)	dprA	2026202..2027389 (+)	1188	WP_002224381.1	DNA-processing protein DprA	Machinery gene
H7969_RS10175 (H7969_10175)	-	2027415..2027876 (+)	462	WP_002215351.1	DUF494 domain-containing protein	-
H7969_RS10180 (H7969_10180)	topA	2027948..2030254 (+)	2307	WP_002224383.1	type I DNA topoisomerase	-
H7969_RS10185 (H7969_10185)	-	2030327..2031022 (-)	696	WP_002216227.1	hypothetical protein	-
H7969_RS10190 (H7969_10190)	-	2031713..2032090 (+)	378	WP_002233408.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 395 a.a.
• Molecular weight: 41908.07 Da
• Isoelectric Point: 6.3083

>NTDB_id=475229 H7969_RS10170 WP_002224381.1 2026202..2027389(+) (dprA) [Neisseria meningitidis strain LNP24198]
MTEDERFAWLQLAFTPYIGAESFLLLLHHFGSAQNALSAPAEQVAALIRHKQALEAWRNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLAQGLTAPPVLFLRGNVRLLHKPSAAIVGSRYATPQAMRIAKDFGRALGGKGIPVVSGMASGIDT
AAHQGALQAEGGTIAVWGTGIDRIYPPANKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLTECLDDILNECPGLLQNTGASSYSINKDTPDTGRRAVQT
AYAPPPAAKMPSEGAAGGTAVGGILDKMGFDPIHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1188 bp

>NTDB_id=475229 H7969_RS10170 WP_002224381.1 2026202..2027389(+) (dprA) [Neisseria meningitidis strain LNP24198]
ATGACAGAGGACGAACGTTTCGCGTGGTTGCAACTGGCTTTTACGCCCTATATCGGTGCGGAAAGTTTCTTGCTGCTGCT
GCACCATTTCGGCAGTGCGCAAAATGCCCTGTCCGCACCGGCGGAACAGGTGGCGGCACTGATACGGCACAAACAGGCGC
TTGAGGCTTGGCGCAATGCGGAAAAACGCGCCTTGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGTCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGGCGCAGGGGCTGACCGCGCCGCCAGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCTATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAGGGCGTTGGGTGGGAAAGGCATTCCCGTCGTGTCGGGTATGGCTTCGGGCATCGACACC
GCCGCCCATCAGGGCGCGTTGCAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACGGGCATAGACCGCATTTATCCGCC
AGCCAACAAAAACCTTGCTTATGAAATCGCCGAAAAAGGACTGATTGTCAGCGAGTTCCCCATCGGCACGCGGCCGTATG
CCGGCAATTTTCCGCGCCGCAACCGTCTGATTGCTGCCCTGTCGCAGGTTACGCTGGTGGTTGAAGCCGCGTTGGAATCC
GGTTCGCTGATTACCGCCGGCCTGGCGGCAGAAATGGGGCGCGAAGTGATGGCGGTACCCGGCTCGATAGACAATCCGCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCGAAACTGACGGAATGTTTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCATCATATTCTATAAATAAGGATACGCCCGACACGGGCCGCCGCGCCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGGGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCCATCCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (341-388)

• DNA recombination-mediator protein A (DNA_processg_A) (79-282)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae MS11	96.962	100	0.97
dprA	Neisseria gonorrhoeae strain FA1090	96.709	100	0.967
dprA	Neisseria meningitidis strain C311	90.68	100	0.911
dprA	Neisseria meningitidis MC58	90.68	100	0.911
dprA	Vibrio cholerae strain A1552	38.287	100	0.385