Detailed information NTG0475225

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: H7969_RS09750
• Genome accession: NZ_CP060280
• Coordinates: 1935418..1936683 (+)
• Length: 421 a.a.
• NCBI ID: WP_002224230.1
• Uniprot ID: A1KR71
• Organism: Neisseria meningitidis strain LNP24198
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1930418..1941683

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7969_RS09730 (H7969_09730)	-	1931149..1932150 (+)	1002	WP_002223261.1	thiamine ABC transporter substrate-binding protein	-
H7969_RS09735 (H7969_09735)	-	1932244..1933092 (+)	849	WP_002215243.1	mechanosensitive ion channel family protein	-
H7969_RS09740 (H7969_09740)	-	1933118..1933603 (+)	486	WP_002215245.1	CinA family protein	-
H7969_RS09745 (H7969_09745)	msrAB	1933705..1935273 (-)	1569	WP_002224229.1	bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB	-
H7969_RS09750 (H7969_09750)	pilA	1935418..1936683 (+)	1266	WP_002224230.1	signal recognition particle-docking protein FtsY	Machinery gene
H7969_RS09755 (H7969_09755)	-	1937662..1937946 (+)	285	WP_002216166.1	GIY-YIG nuclease family protein	-
H7969_RS09760 (H7969_09760)	-	1939294..1939452 (-)	159	WP_153317777.1	hypothetical protein	-

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 45333.62 Da
• Isoelectric Point: 4.5064

>NTDB_id=475225 H7969_RS09750 WP_002224230.1 1935418..1936683(+) (pilA) [Neisseria meningitidis strain LNP24198]
MFSFFRRKKKQETPALEEAQIQETAAKAESETDQVIENIKEEVESLTESVKEQVESAVETVSGAVEQVKETVAEMLSEAE
EAAEKAAEQVEAAKEAIAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GEGIDDLRPFDARAFVDALLD

Nucleotide

• Length: 1266 bp

>NTDB_id=475225 H7969_RS09750 WP_002224230.1 1935418..1936683(+) (pilA) [Neisseria meningitidis strain LNP24198]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCTCAAATTCAGGAAACCGCAGCAAA
AGCAGAGTCCGAAACCGATCAAGTAATTGAAAATATTAAAGAAGAAGTCGAATCTTTAACGGAAAGCGTCAAAGAGCAGG
TCGAATCGGCTGTTGAAACCGTCAGCGGTGCGGTTGAACAAGTAAAGGAAACCGTTGCCGAGATGCTGTCTGAAGCAGAG
GAAGCGGCGGAAAAAGCAGCGGAACAAGTCGAAGCGGCAAAAGAAGCCATTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCAACAACTGAAGAACACAAGCTCGGTTGGGCGGCGCGTTTGAAACAAGGTTTGACCAAATCGC
GCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAAATCGACGAGGATTTGTACGAAGAGCTGGAAACC
GTGCTGATTACCAGCGATATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCTCTGGAAAAACCATTGG
TCTTGCCCGAAACCAAAGAGCCGTTTGTCATCATGCTTGCCGGCATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAA
CTCGCCAAATATTTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGACACTTTCCGCGCCGCCGCCCGTGAGCA
GCTTCAGGCATGGGGCGAACGCAACAACGTTACCGTGATTTCGCAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATG
CCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATCGTGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTG
ATGGAAGAAATCAAAAAAGTGAAACGCGTGCTGCAAAAAGCCATGCCCGACGCGCCGCACGAAATCATCGTCGTGCTTGA
TGCCAACATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTAGGGCTGACCGGTTTAATCGTGACCA
AACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGCCCCGTCCCCGTCCGCTACATCGGCGTG
GGCGAAGGCATAGACGATTTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (221-420)

• SRP54-type protein, helical bundle domain (SRP54_N) (136-202)

3D structure

• AlphaFold DB: A1KR71

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	93.349	100	0.933