Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   H7684_RS12135 Genome accession   NZ_CP060278
Coordinates   2464383..2465099 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain KZN     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2459383..2470099
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7684_RS12105 (H7684_12105) - 2459600..2460226 (+) 627 WP_000522384.1 nitroreductase family protein -
  H7684_RS12110 (H7684_12110) - 2460587..2461372 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  H7684_RS14055 hld 2461972..2462052 (-) 81 WP_000046022.1 delta-hemolysin -
  H7684_RS12120 (H7684_12120) - 2462342..2462905 (+) 564 WP_001105696.1 accessory gene regulator ArgB-like protein -
  H7684_RS12125 (H7684_12125) - 2462908..2463051 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide -
  H7684_RS12130 (H7684_12130) - 2463081..2464364 (+) 1284 WP_000447888.1 sensor histidine kinase -
  H7684_RS12135 (H7684_12135) agrA 2464383..2465099 (+) 717 WP_000688492.1 LytTR family DNA-binding domain-containing protein Regulator
  H7684_RS12140 (H7684_12140) - 2465171..2465280 (+) 110 Protein_2370 hypothetical protein -
  H7684_RS12145 (H7684_12145) - 2465468..2466427 (-) 960 WP_001253312.1 carbohydrate kinase -
  H7684_RS12150 (H7684_12150) - 2466424..2467908 (-) 1485 WP_000141432.1 glycoside hydrolase family 32 protein -
  H7684_RS12155 (H7684_12155) - 2468057..2469007 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=475179 H7684_RS12135 WP_000688492.1 2464383..2465099(+) (agrA) [Staphylococcus aureus strain KZN]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=475179 H7684_RS12135 WP_000688492.1 2464383..2465099(+) (agrA) [Staphylococcus aureus strain KZN]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1