Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   LJP_RS08515 Genome accession   NC_017477
Coordinates   1766592..1768400 (+) Length   602 a.a.
NCBI ID   WP_014567850.1    Uniprot ID   -
Organism   Lactobacillus johnsonii DPC 6026     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1746101..1775126 1766592..1768400 within 0


Gene organization within MGE regions


Location: 1746101..1775126
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LJP_RS08410 (LJP_1603c) - 1746101..1746847 (-) 747 WP_014567842.1 ABC transporter ATP-binding protein -
  LJP_RS08415 (LJP_1604) - 1747087..1748535 (+) 1449 WP_004896569.1 APC family permease -
  LJP_RS08420 (LJP_1605) hflX 1749316..1750596 (+) 1281 WP_004897990.1 GTPase HflX -
  LJP_RS08425 (LJP_1606c) - 1750642..1751850 (-) 1209 WP_004897991.1 L,D-transpeptidase family protein -
  LJP_RS08430 (LJP_1607c) - 1751954..1753210 (-) 1257 WP_004897992.1 C40 family peptidase -
  LJP_RS08435 (LJP_1608c) - 1753404..1753961 (-) 558 WP_004897993.1 guanylate kinase -
  LJP_RS08440 (LJP_1609) - 1754052..1754345 (+) 294 WP_004897994.1 DUF2187 domain-containing protein -
  LJP_RS08445 (LJP_1610) - 1754395..1755924 (+) 1530 WP_014567844.1 O-antigen ligase family protein -
  LJP_RS08450 (LJP_1611c) - 1755994..1756620 (-) 627 WP_004897996.1 LVIS_2131 family protein -
  LJP_RS08455 (LJP_1612) nrdI 1756763..1757224 (+) 462 WP_004897997.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  LJP_RS08460 (LJP_1613) - 1757217..1758158 (+) 942 WP_014567845.1 ribonucleotide-diphosphate reductase subunit beta -
  LJP_RS08465 (LJP_1614c) ltrA 1758234..1759529 (-) 1296 WP_004897912.1 group II intron reverse transcriptase/maturase -
  LJP_RS08470 (LJP_1615c) - 1760122..1760607 (-) 486 WP_004897999.1 hypothetical protein -
  LJP_RS08475 (LJP_1616c) - 1760693..1761034 (-) 342 WP_004898000.1 type II toxin-antitoxin system PemK/MazF family toxin -
  LJP_RS08480 (LJP_1617c) mazE 1761021..1761272 (-) 252 WP_004898001.1 type II toxin-antitoxin system PemI/MazE family antitoxin -
  LJP_RS08485 (LJP_1618c) - 1761504..1761974 (-) 471 WP_004898002.1 threonine/serine exporter family protein -
  LJP_RS08490 (LJP_1619c) - 1761974..1762756 (-) 783 WP_004898003.1 threonine/serine exporter family protein -
  LJP_RS08495 (LJP_1620c) - 1762773..1764320 (-) 1548 WP_014567846.1 ABC-F family ATP-binding cassette domain-containing protein -
  LJP_RS08500 (LJP_1621c) - 1764320..1764703 (-) 384 WP_014567847.1 hypothetical protein -
  LJP_RS08505 (LJP_1622) - 1764927..1765199 (+) 273 WP_014567848.1 hypothetical protein -
  LJP_RS08510 (LJP_1623c) - 1765304..1766428 (-) 1125 WP_014567849.1 LCP family protein -
  LJP_RS08515 (LJP_1624) pepF 1766592..1768400 (+) 1809 WP_014567850.1 oligoendopeptidase F Regulator
  LJP_RS08520 (LJP_1625c) - 1768470..1769981 (-) 1512 WP_004898009.1 L-lactate permease -
  LJP_RS08525 (LJP_1626c) - 1770102..1770893 (-) 792 WP_004898010.1 metal ABC transporter permease -
  LJP_RS08530 (LJP_1627c) - 1770893..1771552 (-) 660 WP_004898011.1 metal ABC transporter ATP-binding protein -
  LJP_RS08535 (LJP_1628c) - 1771591..1772490 (-) 900 WP_004898012.1 metal ABC transporter solute-binding protein, Zn/Mn family -
  LJP_RS08540 (LJP_1629c) - 1772793..1773059 (-) 267 WP_014567852.1 ArsR/SmtB family transcription factor -
  LJP_RS09765 - 1773131..1773930 (+) 800 Protein_1668 IS5 family transposase -
  LJP_RS08550 (LJP_1630) - 1774209..1775126 (+) 918 WP_014567853.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 602 a.a.        Molecular weight: 68625.29 Da        Isoelectric Point: 4.5875

>NTDB_id=47491 LJP_RS08515 WP_014567850.1 1766592..1768400(+) (pepF) [Lactobacillus johnsonii DPC 6026]
MAIPTRNEVSDDLKWDLSRVFKDDQEWEQEYNQVATEIKNLGRFKGNLAKSGQDLYEGITEILSVNRRLEKVYVYATMSS
DVDTSNTHYLGLVAKAQSLANQMSAAISFVDPEILSIPEETLAKFMQDEPRLKEYQHRLEQITKKRPHTLPASEEKIIAA
AGDAMGTSANTFNVLTNSDMEYGYVQDEDGEMVQLSDGLYSLLIQSQDRNVRKNAFDVMYASYGQFENSLASTLSGEVKA
HNFNAQVHKYNSAREAALSENGVPTAVYDTLVKEVNSHLNLLHRYVSLRKKILGLSDLQMYDMYVPLTGEPSLSYNFEEA
KNEARRALAPLGKDYLEHVDYIFNNRVIDVVESQNKVTGAYSGGSYDTDPYELLNWEDNLDSLYTLVHETGHSVHSWYTR
NTQPYVYGDYPIFVAEIASTTNENILTEYFLDKITDPKTRAFVLNHYLDSFKGTLFRQTQFAEFEQFIHEADANGQPLTA
DVLDEFYGNLNQRYYGDSVEPGGEIAKEWARIPHFYYNFYVYQYATGFAAATALANNVVHGTDEERTAYINFLKAGSSDY
PTEIMKRAGVDMTKADYLRDAFNTFEKRLNEFEKIVNELKTI

Nucleotide


Download         Length: 1809 bp        

>NTDB_id=47491 LJP_RS08515 WP_014567850.1 1766592..1768400(+) (pepF) [Lactobacillus johnsonii DPC 6026]
ATGGCTATTCCAACAAGAAATGAAGTATCTGATGATCTCAAATGGGATCTTAGTCGTGTTTTTAAAGACGATCAGGAATG
GGAACAAGAATATAATCAGGTCGCAACCGAAATTAAAAATTTAGGTAGATTTAAGGGAAATCTTGCTAAATCTGGTCAAG
ATTTATATGAAGGAATTACAGAAATTTTATCTGTAAATCGTCGTTTAGAAAAAGTGTACGTTTATGCTACTATGTCAAGC
GACGTTGATACTAGTAATACTCATTATCTAGGCCTCGTTGCTAAAGCTCAAAGCTTAGCTAACCAGATGAGCGCCGCTAT
CTCTTTTGTCGATCCTGAAATTTTATCTATCCCAGAAGAAACACTTGCTAAATTTATGCAAGATGAGCCCCGTTTAAAAG
AGTATCAACATCGACTTGAACAAATTACTAAGAAACGTCCTCATACTTTACCAGCAAGTGAAGAAAAAATTATTGCCGCT
GCTGGAGATGCAATGGGAACTTCCGCTAATACTTTCAATGTTTTAACTAATTCTGATATGGAATACGGCTATGTTCAAGA
TGAAGACGGAGAGATGGTCCAATTATCTGATGGCTTATATTCACTTCTAATTCAGTCACAAGATAGAAATGTTCGCAAAA
ATGCATTTGATGTTATGTATGCAAGCTATGGCCAGTTTGAAAATAGTCTCGCTTCAACTTTATCAGGTGAAGTAAAAGCC
CACAATTTTAATGCTCAAGTACATAAATATAATTCAGCTCGAGAGGCTGCTTTAAGTGAAAATGGCGTACCAACAGCTGT
TTACGATACATTGGTTAAAGAGGTAAATAGTCACCTCAACTTACTTCATCGCTACGTTAGTTTAAGAAAAAAGATTTTAG
GTCTTTCTGATTTACAAATGTATGATATGTATGTTCCATTAACAGGTGAGCCCAGTCTTTCTTATAACTTTGAAGAAGCA
AAAAATGAAGCTAGACGAGCCTTAGCGCCATTAGGAAAAGATTACCTCGAACATGTTGATTACATCTTTAATAATCGTGT
AATTGATGTGGTTGAAAGCCAAAATAAGGTAACAGGCGCTTATTCTGGTGGTTCCTATGATACTGATCCATATGAATTAT
TAAATTGGGAGGATAATCTTGATTCTCTATATACTCTAGTTCATGAAACTGGACACTCAGTGCATTCCTGGTATACAAGA
AATACTCAACCATATGTATATGGAGACTACCCAATTTTTGTTGCTGAAATTGCATCAACAACTAATGAAAATATTTTAAC
TGAATACTTCTTAGATAAAATTACCGATCCTAAAACACGCGCATTTGTTTTGAATCACTATCTTGATTCATTTAAGGGTA
CACTTTTCCGTCAAACACAATTTGCAGAATTTGAGCAGTTTATTCATGAAGCTGATGCAAATGGTCAACCATTAACTGCC
GATGTTCTTGATGAATTTTATGGCAATTTAAACCAAAGATATTACGGTGATAGTGTAGAACCGGGCGGAGAGATTGCTAA
AGAATGGGCCCGTATTCCTCACTTCTATTACAACTTCTATGTTTACCAATATGCAACAGGTTTTGCTGCTGCTACAGCCC
TTGCAAATAATGTTGTTCATGGTACGGACGAAGAACGTACAGCTTATATTAATTTCTTAAAGGCTGGTTCTTCAGATTAT
CCAACAGAAATAATGAAACGTGCCGGTGTCGATATGACAAAGGCTGATTACTTAAGAGACGCATTTAATACTTTTGAAAA
ACGACTTAATGAGTTTGAAAAAATCGTTAATGAACTGAAAACAATCTAG

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(113-181)

Peptidase family M3 (Peptidase_M3)

(203-583)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

51.689

98.339

0.508

Multiple sequence alignment