Detailed information NTG0474180

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: H6X75_RS09615
• Genome accession: NZ_CP060156
• Coordinates: 1912899..1913936 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727276.1
• Uniprot ID: A0AAQ2ZXI6
• Organism: Streptococcus pneumoniae strain PZ900700608
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1907899..1918936

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H6X75_RS09590 (H6X75_09585)	-	1908638..1909969 (-)	1332	WP_000390039.1	hemolysin family protein	-
H6X75_RS09595 (H6X75_09590)	endA	1910260..1911084 (-)	825	WP_001036786.1	DNA-entry nuclease EndA	Machinery gene
H6X75_RS09600 (H6X75_09595)	-	1911123..1911311 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
H6X75_RS09605 (H6X75_09600)	murA	1911304..1912587 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H6X75_RS09610 (H6X75_09605)	-	1912611..1912841 (-)	231	WP_000250392.1	DUF1146 family protein	-
H6X75_RS09615 (H6X75_09610)	sepM	1912899..1913936 (-)	1038	WP_000727276.1	SepM family pheromone-processing serine protease	Regulator
H6X75_RS09620 (H6X75_09615)	coaD	1913920..1914408 (-)	489	WP_001280742.1	pantetheine-phosphate adenylyltransferase	-
H6X75_RS09625 (H6X75_09620)	rsmD	1914398..1914937 (-)	540	WP_000706962.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
H6X75_RS09630 (H6X75_09625)	asnA	1915002..1915994 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
H6X75_RS09635 (H6X75_09630)	-	1916106..1916789 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
H6X75_RS09640 (H6X75_09635)	-	1916845..1917585 (-)	741	WP_000152701.1	RNA methyltransferase	-
H6X75_RS09645 (H6X75_09640)	-	1917619..1917897 (+)	279	WP_001174613.1	acylphosphatase	-
H6X75_RS09650 (H6X75_09645)	yidC	1917975..1918901 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37553.61 Da
• Isoelectric Point: 5.0724

>NTDB_id=474180 H6X75_RS09615 WP_000727276.1 1912899..1913936(-) (sepM) [Streptococcus pneumoniae strain PZ900700608]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=474180 H6X75_RS09615 WP_000727276.1 1912899..1913936(-) (sepM) [Streptococcus pneumoniae strain PZ900700608]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCTGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588